Miles JJ - Search Results

1

Antibody stabilization of peptide-MHC multimers reveals functional T cells bearing extremely low-affinity TCRs.

Tungatt K, Bianchi V, Crowther MD, Powell WE, Schauenburg AJ, Trimby A, Donia M, Miles JJ, Holland CJ, Cole DK, Godkin AJ, Peakman M, Straten PT, Svane IM, Sewell AK, Dolton G. Tungatt K, et al. Among authors: miles jj. J Immunol. 2015 Jan 1;194(1):463-74. doi: 10.4049/jimmunol.1401785. Epub 2014 Dec 1. J Immunol. 2015. PMID: 25452566 Free PMC article.

2

Promiscuous CTL recognition of viral epitopes on multiple human leukocyte antigens: biological validation of the proposed HLA A24 supertype.

Burrows SR, Elkington RA, Miles JJ, Green KJ, Walker S, Haryana SM, Moss DJ, Dunckley H, Burrows JM, Khanna R. Burrows SR, et al. Among authors: miles jj. J Immunol. 2003 Aug 1;171(3):1407-12. doi: 10.4049/jimmunol.171.3.1407. J Immunol. 2003. PMID: 12874232

3

CTL recognition of a bulged viral peptide involves biased TCR selection.

Miles JJ, Elhassen D, Borg NA, Silins SL, Tynan FE, Burrows JM, Purcell AW, Kjer-Nielsen L, Rossjohn J, Burrows SR, McCluskey J. Miles JJ, et al. J Immunol. 2005 Sep 15;175(6):3826-34. doi: 10.4049/jimmunol.175.6.3826. J Immunol. 2005. PMID: 16148129

4

TCR alpha genes direct MHC restriction in the potent human T cell response to a class I-bound viral epitope.

Miles JJ, Borg NA, Brennan RM, Tynan FE, Kjer-Nielsen L, Silins SL, Bell MJ, Burrows JM, McCluskey J, Rossjohn J, Burrows SR. Miles JJ, et al. J Immunol. 2006 Nov 15;177(10):6804-14. doi: 10.4049/jimmunol.177.10.6804. J Immunol. 2006. PMID: 17082594

5

Germ line-governed recognition of a cancer epitope by an immunodominant human T-cell receptor.

Cole DK, Yuan F, Rizkallah PJ, Miles JJ, Gostick E, Price DA, Gao GF, Jakobsen BK, Sewell AK. Cole DK, et al. Among authors: miles jj. J Biol Chem. 2009 Oct 2;284(40):27281-9. doi: 10.1074/jbc.M109.022509. Epub 2009 Jul 15. J Biol Chem. 2009. PMID: 19605354 Free PMC article.

6

MHC class I molecules with Superenhanced CD8 binding properties bypass the requirement for cognate TCR recognition and nonspecifically activate CTLs.

Wooldridge L, Clement M, Lissina A, Edwards ES, Ladell K, Ekeruche J, Hewitt RE, Laugel B, Gostick E, Cole DK, Debets R, Berrevoets C, Miles JJ, Burrows SR, Price DA, Sewell AK. Wooldridge L, et al. Among authors: miles jj. J Immunol. 2010 Apr 1;184(7):3357-66. doi: 10.4049/jimmunol.0902398. Epub 2010 Feb 26. J Immunol. 2010. PMID: 20190139 Free PMC article.

7

Modification of MHC anchor residues generates heteroclitic peptides that alter TCR binding and T cell recognition.

Cole DK, Edwards ES, Wynn KK, Clement M, Miles JJ, Ladell K, Ekeruche J, Gostick E, Adams KJ, Skowera A, Peakman M, Wooldridge L, Price DA, Sewell AK. Cole DK, et al. Among authors: miles jj. J Immunol. 2010 Aug 15;185(4):2600-10. doi: 10.4049/jimmunol.1000629. Epub 2010 Jul 16. J Immunol. 2010. PMID: 20639478 Free PMC article.

8

Genetic and structural basis for selection of a ubiquitous T cell receptor deployed in Epstein-Barr virus infection.

Miles JJ, Bulek AM, Cole DK, Gostick E, Schauenburg AJ, Dolton G, Venturi V, Davenport MP, Tan MP, Burrows SR, Wooldridge L, Price DA, Rizkallah PJ, Sewell AK. Miles JJ, et al. PLoS Pathog. 2010 Nov 18;6(11):e1001198. doi: 10.1371/journal.ppat.1001198. PLoS Pathog. 2010. PMID: 21124993 Free PMC article.

9

Real time detection of peptide-MHC dissociation reveals that improvement of primary MHC-binding residues can have a minimal, or no, effect on stability.

Miles KM, Miles JJ, Madura F, Sewell AK, Cole DK. Miles KM, et al. Among authors: miles jj. Mol Immunol. 2011 Jan;48(4):728-32. doi: 10.1016/j.molimm.2010.11.004. Epub 2010 Dec 4. Mol Immunol. 2011. PMID: 21130497 Free PMC article.

10

Antigen-driven patterns of TCR bias are shared across diverse outcomes of human hepatitis C virus infection.

Miles JJ, Thammanichanond D, Moneer S, Nivarthi UK, Kjer-Nielsen L, Tracy SL, Aitken CK, Brennan RM, Zeng W, Marquart L, Jackson D, Burrows SR, Bowden DS, Torresi J, Hellard M, Rossjohn J, McCluskey J, Bharadwaj M. Miles JJ, et al. J Immunol. 2011 Jan 15;186(2):901-12. doi: 10.4049/jimmunol.1003167. Epub 2010 Dec 15. J Immunol. 2011. PMID: 21160049

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