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Loss of TLR3 aggravates CHIKV replication and pathology due to an altered virus-specific neutralizing antibody response.
Her Z, Teng TS, Tan JJ, Teo TH, Kam YW, Lum FM, Lee WW, Gabriel C, Melchiotti R, Andiappan AK, Lulla V, Lulla A, Win MK, Chow A, Biswas SK, Leo YS, Lecuit M, Merits A, Rénia L, Ng LF. Her Z, et al. Among authors: lulla v, lulla a. EMBO Mol Med. 2015 Jan;7(1):24-41. doi: 10.15252/emmm.201404459. EMBO Mol Med. 2015. PMID: 25452586 Free PMC article.
The highly conserved stem-loop II motif is important for the lifecycle of astroviruses but dispensable for SARS-CoV-2.
Janowski AB, Jiang H, Fujii C, Owen MC, Bricker TL, Darling TL, Harastani HH, Seehra K, Tahan S, Jung A, Febles B, Blatter JA, Handley SA, Parikh BA, Lulla V, Boon AC, Wang D. Janowski AB, et al. Among authors: lulla v. bioRxiv [Preprint]. 2022 May 2:2022.04.30.486882. doi: 10.1101/2022.04.30.486882. bioRxiv. 2022. Update in: J Virol. 2023 Jun 29;97(6):e0063523. doi: 10.1128/jvi.00635-23 PMID: 35547847 Free PMC article. Updated. Preprint.
39 results