Cravatt BF - Search Results

1

Target-based screen against a periplasmic serine protease that regulates intrabacterial pH homeostasis in Mycobacterium tuberculosis.

Zhao N, Darby CM, Small J, Bachovchin DA, Jiang X, Burns-Huang KE, Botella H, Ehrt S, Boger DL, Anderson ED, Cravatt BF, Speers AE, Fernandez-Vega V, Hodder PS, Eberhart C, Rosen H, Spicer TP, Nathan CF. Zhao N, et al. Among authors: cravatt bf. ACS Chem Biol. 2015 Feb 20;10(2):364-71. doi: 10.1021/cb500746z. Epub 2014 Dec 5. ACS Chem Biol. 2015. PMID: 25457457 Free PMC article.

2

An endogenous sleep-inducing compound is a novel competitive inhibitor of fatty acid amide hydrolase.

Patricelli MP, Patterson JE, Boger DL, Cravatt BF. Patricelli MP, et al. Among authors: cravatt bf. Bioorg Med Chem Lett. 1998 Mar 17;8(6):613-8. doi: 10.1016/s0960-894x(98)00073-0. Bioorg Med Chem Lett. 1998. PMID: 9871570

3

Oleamide: an endogenous sleep-inducing lipid and prototypical member of a new class of biological signaling molecules.

Boger DL, Henriksen SJ, Cravatt BF. Boger DL, et al. Among authors: cravatt bf. Curr Pharm Des. 1998 Aug;4(4):303-14. Curr Pharm Des. 1998. PMID: 10197045 Review.

4

Activity-based protein profiling in vivo using a copper(i)-catalyzed azide-alkyne [3 + 2] cycloaddition.

Speers AE, Adam GC, Cravatt BF. Speers AE, et al. Among authors: cravatt bf. J Am Chem Soc. 2003 Apr 23;125(16):4686-7. doi: 10.1021/ja034490h. J Am Chem Soc. 2003. PMID: 12696868

5

Chemical strategies for activity-based proteomics.

Speers AE, Cravatt BF. Speers AE, et al. Among authors: cravatt bf. Chembiochem. 2004 Jan 3;5(1):41-7. doi: 10.1002/cbic.200300721. Chembiochem. 2004. PMID: 14695510 Review.

6

Profiling enzyme activities in vivo using click chemistry methods.

Speers AE, Cravatt BF. Speers AE, et al. Among authors: cravatt bf. Chem Biol. 2004 Apr;11(4):535-46. doi: 10.1016/j.chembiol.2004.03.012. Chem Biol. 2004. PMID: 15123248

7

A tandem orthogonal proteolysis strategy for high-content chemical proteomics.

Speers AE, Cravatt BF. Speers AE, et al. Among authors: cravatt bf. J Am Chem Soc. 2005 Jul 20;127(28):10018-9. doi: 10.1021/ja0532842. J Am Chem Soc. 2005. PMID: 16011363 Free PMC article.

8

Tandem orthogonal proteolysis-activity-based protein profiling (TOP-ABPP)--a general method for mapping sites of probe modification in proteomes.

Weerapana E, Speers AE, Cravatt BF. Weerapana E, et al. Among authors: cravatt bf. Nat Protoc. 2007;2(6):1414-25. doi: 10.1038/nprot.2007.194. Nat Protoc. 2007. PMID: 17545978

9

Ranking the selectivity of PubChem screening hits by activity-based protein profiling: MMP13 as a case study.

Nakai R, Salisbury CM, Rosen H, Cravatt BF. Nakai R, et al. Among authors: cravatt bf. Bioorg Med Chem. 2009 Feb 1;17(3):1101-8. doi: 10.1016/j.bmc.2008.03.018. Epub 2008 Mar 8. Bioorg Med Chem. 2009. PMID: 18364257 Free PMC article.

10

Exploration of a fundamental substituent effect of alpha-ketoheterocycle enzyme inhibitors: Potent and selective inhibitors of fatty acid amide hydrolase.

DeMartino JK, Garfunkle J, Hochstatter DG, Cravatt BF, Boger DL. DeMartino JK, et al. Among authors: cravatt bf. Bioorg Med Chem Lett. 2008 Nov 15;18(22):5842-6. doi: 10.1016/j.bmcl.2008.06.084. Epub 2008 Jun 28. Bioorg Med Chem Lett. 2008. PMID: 18639454 Free PMC article.

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