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Inhibition of Dll4 signalling inhibits tumour growth by deregulating angiogenesis.
Ridgway J, Zhang G, Wu Y, Stawicki S, Liang WC, Chanthery Y, Kowalski J, Watts RJ, Callahan C, Kasman I, Singh M, Chien M, Tan C, Hongo JA, de Sauvage F, Plowman G, Yan M. Ridgway J, et al. Among authors: yan m. Nature. 2006 Dec 21;444(7122):1083-7. doi: 10.1038/nature05313. Nature. 2006. PMID: 17183323
Chronic DLL4 blockade induces vascular neoplasms.
Yan M, Callahan CA, Beyer JC, Allamneni KP, Zhang G, Ridgway JB, Niessen K, Plowman GD. Yan M, et al. Nature. 2010 Feb 11;463(7282):E6-7. doi: 10.1038/nature08751. Nature. 2010. PMID: 20147986
Balancing Efficacy and Safety of an Anti-DLL4 Antibody through Pharmacokinetic Modulation.
Couch JA, Zhang G, Beyer JC, de Zafra CL, Gupta P, Kamath AV, Lewin-Koh N, Tarrant J, Allamneni KP, Cain G, Yee S, Ross S, Cook R, Tsai SP, Ruppel J, Ridgway JB, Paluch M, Hass PE, Franklin J, Yan M. Couch JA, et al. Among authors: yan m. Clin Cancer Res. 2016 Mar 15;22(6):1469-79. doi: 10.1158/1078-0432.CCR-15-1380. Epub 2015 Nov 20. Clin Cancer Res. 2016. PMID: 26589434
Harnessing MerTK agonism for targeted therapeutics.
Kedage V, Ellerman D, Chen Y, Liang WC, Borneo J, Wu Y, Yan M. Kedage V, et al. Among authors: yan m. MAbs. 2020 Jan-Dec;12(1):1685832. doi: 10.1080/19420862.2019.1685832. MAbs. 2020. PMID: 31852344 Free PMC article.
Targeted IgMs agonize ocular targets with extended vitreal exposure.
Chen Y, Paluch M, Zorn JA, Rajan S, Leonard B, Estevez A, Brady J, Chiu H, Phung W, Famili A, Yan M, Ciferri C, Matsumoto ML, Lazar GA, Crowell S, Hass P, Agard NJ. Chen Y, et al. Among authors: yan m. MAbs. 2020 Jan-Dec;12(1):1818436. doi: 10.1080/19420862.2020.1818436. MAbs. 2020. PMID: 32936727 Free PMC article.
CLEC5a-directed bispecific antibody for effective cellular phagocytosis.
Kedage V, Ellerman D, Fei M, Liang WC, Zhang G, Cheng E, Zhang J, Chen Y, Huang H, Lee WP, Wu Y, Yan M. Kedage V, et al. Among authors: yan m. MAbs. 2022 Jan-Dec;14(1):2040083. doi: 10.1080/19420862.2022.2040083. MAbs. 2022. PMID: 35293277 Free PMC article.
7,185 results