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Biochemical and cellular analysis of Ogden syndrome reveals downstream Nt-acetylation defects.
Myklebust LM, Van Damme P, Støve SI, Dörfel MJ, Abboud A, Kalvik TV, Grauffel C, Jonckheere V, Wu Y, Swensen J, Kaasa H, Liszczak G, Marmorstein R, Reuter N, Lyon GJ, Gevaert K, Arnesen T. Myklebust LM, et al. Among authors: marmorstein r. Hum Mol Genet. 2015 Apr 1;24(7):1956-76. doi: 10.1093/hmg/ddu611. Epub 2014 Dec 8. Hum Mol Genet. 2015. PMID: 25489052 Free PMC article.
Virtual ligand screening of the p300/CBP histone acetyltransferase: identification of a selective small molecule inhibitor.
Bowers EM, Yan G, Mukherjee C, Orry A, Wang L, Holbert MA, Crump NT, Hazzalin CA, Liszczak G, Yuan H, Larocca C, Saldanha SA, Abagyan R, Sun Y, Meyers DJ, Marmorstein R, Mahadevan LC, Alani RM, Cole PA. Bowers EM, et al. Among authors: marmorstein r. Chem Biol. 2010 May 28;17(5):471-82. doi: 10.1016/j.chembiol.2010.03.006. Chem Biol. 2010. PMID: 20534345 Free PMC article.
MYST protein acetyltransferase activity requires active site lysine autoacetylation.
Yuan H, Rossetto D, Mellert H, Dang W, Srinivasan M, Johnson J, Hodawadekar S, Ding EC, Speicher K, Abshiru N, Perry R, Wu J, Yang C, Zheng YG, Speicher DW, Thibault P, Verreault A, Johnson FB, Berger SL, Sternglanz R, McMahon SB, Côté J, Marmorstein R. Yuan H, et al. Among authors: marmorstein r. EMBO J. 2012 Jan 4;31(1):58-70. doi: 10.1038/emboj.2011.382. Epub 2011 Oct 21. EMBO J. 2012. PMID: 22020126 Free PMC article.
236 results