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Page 1
Allosteric activation of ADAMTS13 by von Willebrand factor.
Muia J, Zhu J, Gupta G, Haberichter SL, Friedman KD, Feys HB, Deforche L, Vanhoorelbeke K, Westfield LA, Roth R, Tolia NH, Heuser JE, Sadler JE. Muia J, et al. Proc Natl Acad Sci U S A. 2014 Dec 30;111(52):18584-9. doi: 10.1073/pnas.1413282112. Epub 2014 Dec 15. Proc Natl Acad Sci U S A. 2014. PMID: 25512528 Free PMC article.
Linker regions and flexibility around the metalloprotease domain account for conformational activation of ADAMTS-13.
Deforche L, Roose E, Vandenbulcke A, Vandeputte N, Feys HB, Springer TA, Mi LZ, Muia J, Sadler JE, Soejima K, Rottensteiner H, Deckmyn H, De Meyer SF, Vanhoorelbeke K. Deforche L, et al. Among authors: muia j. J Thromb Haemost. 2015 Nov;13(11):2063-75. doi: 10.1111/jth.13149. Epub 2015 Oct 20. J Thromb Haemost. 2015. PMID: 26391536 Free PMC article.
ADAMTS13 inhibition to treat acquired von Willebrand syndrome during mechanical circulatory support device implantation.
Deconinck SJ, Nix C, Barth S, Bennek-Schöpping E, Rauch A, Schelpe AS, Roose E, Feys HB, Pareyn I, Vandenbulcke A, Muia J, Vandenbriele C, Susen S, Meyns B, Tersteeg C, Jacobs S, De Meyer SF, Vanhoorelbeke K. Deconinck SJ, et al. Among authors: muia j. J Thromb Haemost. 2022 Dec;20(12):2797-2809. doi: 10.1111/jth.15889. Epub 2022 Oct 17. J Thromb Haemost. 2022. PMID: 36128768 Free PMC article.
Plasma and rhADAMTS13 reduce trauma-induced organ failure by restoring the ADAMTS13-VWF axis.
Kleinveld DJB, Simons DDG, Dekimpe C, Deconinck SJ, Sloos PH, Maas MAW, Kers J, Muia J, Brohi K, Voorberg J, Vanhoorelbeke K, Hollmann MW, Juffermans NP; BloodNet. Kleinveld DJB, et al. Among authors: muia j. Blood Adv. 2021 Sep 14;5(17):3478-3491. doi: 10.1182/bloodadvances.2021004404. Blood Adv. 2021. PMID: 34505883 Free PMC article.
Adjuvant low-dose rituximab and plasma exchange for acquired TTP.
Zwicker JI, Muia J, Dolatshahi L, Westfield LA, Nieters P, Rodrigues A, Hamdan A, Antun AG, Metjian A, Sadler JE; ART Investigators. Zwicker JI, et al. Among authors: muia j. Blood. 2019 Sep 26;134(13):1106-1109. doi: 10.1182/blood.2019000795. Epub 2019 Jul 22. Blood. 2019. PMID: 31331919 Free PMC article. Clinical Trial. No abstract available.
Exciting times for the ISTH early career professionals.
Kulkarni K, Chiasakul T, Riva N, Eslick R, Casari C; ISTH Early Career Committee. Kulkarni K, et al. J Thromb Haemost. 2020 Oct;18(10):2437-2438. doi: 10.1111/jth.15070. J Thromb Haemost. 2020. PMID: 33460230 Free article. No abstract available.
18 results