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Frequency of COL4A3/COL4A4 mutations amongst families segregating glomerular microscopic hematuria and evidence for activation of the unfolded protein response. Focal and segmental glomerulosclerosis is a frequent development during ageing.
Papazachariou L, Demosthenous P, Pieri M, Papagregoriou G, Savva I, Stavrou C, Zavros M, Athanasiou Y, Ioannou K, Patsias C, Panagides A, Potamitis C, Demetriou K, Prikis M, Hadjigavriel M, Kkolou M, Loukaidou P, Pastelli A, Michael A, Lazarou A, Arsali M, Damianou L, Goutziamani I, Soloukides A, Yioukas L, Elia A, Zouvani I, Polycarpou P, Pierides A, Voskarides K, Deltas C. Papazachariou L, et al. Among authors: savva i. PLoS One. 2014 Dec 16;9(12):e115015. doi: 10.1371/journal.pone.0115015. eCollection 2014. PLoS One. 2014. PMID: 25514610 Free PMC article.
Evidence for activation of the unfolded protein response in collagen IV nephropathies.
Pieri M, Stefanou C, Zaravinos A, Erguler K, Stylianou K, Lapathitis G, Karaiskos C, Savva I, Paraskeva R, Dweep H, Sticht C, Anastasiadou N, Zouvani I, Goumenos D, Felekkis K, Saleem M, Voskarides K, Gretz N, Deltas C. Pieri M, et al. Among authors: savva i. J Am Soc Nephrol. 2014 Feb;25(2):260-75. doi: 10.1681/ASN.2012121217. Epub 2013 Nov 21. J Am Soc Nephrol. 2014. PMID: 24262798 Free PMC article.
RAAS inhibition and the course of Alport syndrome.
Savva I, Pierides A, Deltas C. Savva I, et al. Pharmacol Res. 2016 May;107:205-210. doi: 10.1016/j.phrs.2016.03.017. Epub 2016 Mar 16. Pharmacol Res. 2016. PMID: 26995302 Review.
Clinical course and outcome after kidney transplantation in patients with C3 glomerulonephritis due to CFHR5 nephropathy.
Frangou E, Varnavidou-Nicolaidou A, Petousis P, Soloukides A, Theophanous E, Savva I, Michael N, Toumasi E, Georgiou D, Stylianou G, Mean R, Anastasiadou N, Athanasiou Y, Zavros M, Kyriacou K, Deltas C, Hadjianastassiou V. Frangou E, et al. Among authors: savva i. Nephrol Dial Transplant. 2019 Oct 1;34(10):1780-1788. doi: 10.1093/ndt/gfz021. Nephrol Dial Transplant. 2019. PMID: 30844074
A glycine substitution in the collagenous domain of Col4a3 in mice recapitulates late onset Alport syndrome.
Odiatis C, Savva I, Pieri M, Ioannou P, Petrou P, Papagregoriou G, Antoniadou K, Makrides N, Stefanou C, Ljubanović DG, Nikolaou G, Borza DB, Stylianou K, Gross O, Deltas C. Odiatis C, et al. Among authors: savva i. Matrix Biol Plus. 2020 Dec 30;9:100053. doi: 10.1016/j.mbplus.2020.100053. eCollection 2021 Feb. Matrix Biol Plus. 2020. PMID: 33718859 Free PMC article.
Advances and unmet needs in genetic, basic and clinical science in Alport syndrome: report from the 2015 International Workshop on Alport Syndrome.
Gross O, Kashtan CE, Rheault MN, Flinter F, Savige J, Miner JH, Torra R, Ars E, Deltas C, Savva I, Perin L, Renieri A, Ariani F, Mari F, Baigent C, Judge P, Knebelman B, Heidet L, Lagas S, Blatt D, Ding J, Zhang Y, Gale DP, Prunotto M, Xue Y, Schachter AD, Morton LCG, Blem J, Huang M, Liu S, Vallee S, Renault D, Schifter J, Skelding J, Gear S, Friede T, Turner AN, Lennon R. Gross O, et al. Among authors: savva i. Nephrol Dial Transplant. 2017 Jun 1;32(6):916-924. doi: 10.1093/ndt/gfw095. Nephrol Dial Transplant. 2017. PMID: 27190345 Free PMC article.
Novel GLA Deletion in a Cypriot Female Presenting with Cornea Verticillata.
Georgiou T, Mavrikiou G, Alexandrou A, Spanou-Aristidou E, Savva I, Christodoulides T, Krasia M, Christophidou-Anastasiadou V, Sismani C, Drousiotou A, Tanteles GA. Georgiou T, et al. Among authors: savva i. Case Rep Genet. 2016;2016:5208312. doi: 10.1155/2016/5208312. Epub 2016 Mar 30. Case Rep Genet. 2016. PMID: 27123349 Free PMC article.
26 results