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Complex-based analysis of dysregulated cellular processes in cancer.
Srihari S, Madhamshettiwar PB, Song S, Liu C, Simpson PT, Khanna KK, Ragan MA. Srihari S, et al. Among authors: madhamshettiwar pb. BMC Syst Biol. 2014;8 Suppl 4(Suppl 4):S1. doi: 10.1186/1752-0509-8-S4-S1. Epub 2014 Dec 8. BMC Syst Biol. 2014. PMID: 25521701 Free PMC article.
RMaNI: Regulatory Module Network Inference framework.
Madhamshettiwar PB, Maetschke SR, Davis MJ, Ragan MA. Madhamshettiwar PB, et al. BMC Bioinformatics. 2013;14 Suppl 16(Suppl 16):S14. doi: 10.1186/1471-2105-14-S16-S14. Epub 2013 Oct 22. BMC Bioinformatics. 2013. PMID: 24564496 Free PMC article.
INsPeCT: INtegrative Platform for Cancer Transcriptomics.
Madhamshettiwar PB, Maetschke SR, Davis MJ, Reverter A, Ragan MA. Madhamshettiwar PB, et al. Cancer Inform. 2014 Mar 12;13:59-66. doi: 10.4137/CIN.S13630. eCollection 2014. Cancer Inform. 2014. PMID: 24653643 Free PMC article.
The RNA polymerase I transcription inhibitor CX-5461 cooperates with topoisomerase 1 inhibition by enhancing the DNA damage response in homologous recombination-proficient high-grade serous ovarian cancer.
Yan S, Xuan J, Brajanovski N, Tancock MRC, Madhamshettiwar PB, Simpson KJ, Ellis S, Kang J, Cullinane C, Sheppard KE, Hannan KM, Hannan RD, Sanij E, Pearson RB, Chan KT. Yan S, et al. Among authors: madhamshettiwar pb. Br J Cancer. 2021 Feb;124(3):616-627. doi: 10.1038/s41416-020-01158-z. Epub 2020 Nov 11. Br J Cancer. 2021. PMID: 33173151 Free PMC article.
A functional genetic screen defines the AKT-induced senescence signaling network.
Chan KT, Blake S, Zhu H, Kang J, Trigos AS, Madhamshettiwar PB, Diesch J, Paavolainen L, Horvath P, Hannan RD, George AJ, Sanij E, Hannan KM, Simpson KJ, Pearson RB. Chan KT, et al. Among authors: madhamshettiwar pb. Cell Death Differ. 2020 Feb;27(2):725-741. doi: 10.1038/s41418-019-0384-8. Epub 2019 Jul 8. Cell Death Differ. 2020. PMID: 31285545 Free PMC article.
Systematic Screening Identifies Dual PI3K and mTOR Inhibition as a Conserved Therapeutic Vulnerability in Osteosarcoma.
Gupte A, Baker EK, Wan SS, Stewart E, Loh A, Shelat AA, Gould CM, Chalk AM, Taylor S, Lackovic K, Karlström Å, Mutsaers AJ, Desai J, Madhamshettiwar PB, Zannettino AC, Burns C, Huang DC, Dyer MA, Simpson KJ, Walkley CR. Gupte A, et al. Among authors: madhamshettiwar pb. Clin Cancer Res. 2015 Jul 15;21(14):3216-29. doi: 10.1158/1078-0432.CCR-14-3026. Epub 2015 Apr 10. Clin Cancer Res. 2015. PMID: 25862761 Free PMC article.
14 results