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Pharmacokinetic, pharmacodynamic and biomarker evaluation of transforming growth factor-β receptor I kinase inhibitor, galunisertib, in phase 1 study in patients with advanced cancer.
Rodón J, Carducci M, Sepulveda-Sánchez JM, Azaro A, Calvo E, Seoane J, Braña I, Sicart E, Gueorguieva I, Cleverly A, Pillay NS, Desaiah D, Estrem ST, Paz-Ares L, Holdhoff M, Blakeley J, Lahn MM, Baselga J. Rodón J, et al. Among authors: blakeley j. Invest New Drugs. 2015 Apr;33(2):357-70. doi: 10.1007/s10637-014-0192-4. Epub 2014 Dec 23. Invest New Drugs. 2015. PMID: 25529192 Free PMC article. Clinical Trial.
First-in-human dose study of the novel transforming growth factor-β receptor I kinase inhibitor LY2157299 monohydrate in patients with advanced cancer and glioma.
Rodon J, Carducci MA, Sepulveda-Sánchez JM, Azaro A, Calvo E, Seoane J, Braña I, Sicart E, Gueorguieva I, Cleverly AL, Pillay NS, Desaiah D, Estrem ST, Paz-Ares L, Holdhoff M, Blakeley J, Lahn MM, Baselga J. Rodon J, et al. Among authors: blakeley j. Clin Cancer Res. 2015 Feb 1;21(3):553-60. doi: 10.1158/1078-0432.CCR-14-1380. Epub 2014 Nov 25. Clin Cancer Res. 2015. PMID: 25424852 Free PMC article. Clinical Trial.
Mebendazole and temozolomide in patients with newly diagnosed high-grade gliomas: results of a phase 1 clinical trial.
Gallia GL, Holdhoff M, Brem H, Joshi AD, Hann CL, Bai RY, Staedtke V, Blakeley JO, Sengupta S, Jarrell TC, Wollett J, Szajna K, Helie N, Mattox AK, Ye X, Rudek MA, Riggins GJ. Gallia GL, et al. Among authors: blakeley jo. Neurooncol Adv. 2020 Nov 12;3(1):vdaa154. doi: 10.1093/noajnl/vdaa154. eCollection 2021 Jan-Dec. Neurooncol Adv. 2020. PMID: 33506200 Free PMC article.
Identifying Recurrent Malignant Glioma after Treatment Using Amide Proton Transfer-Weighted MR Imaging: A Validation Study with Image-Guided Stereotactic Biopsy.
Jiang S, Eberhart CG, Lim M, Heo HY, Zhang Y, Blair L, Wen Z, Holdhoff M, Lin D, Huang P, Qin H, Quinones-Hinojosa A, Weingart JD, Barker PB, Pomper MG, Laterra J, van Zijl PCM, Blakeley JO, Zhou J. Jiang S, et al. Among authors: blakeley jo. Clin Cancer Res. 2019 Jan 15;25(2):552-561. doi: 10.1158/1078-0432.CCR-18-1233. Epub 2018 Oct 26. Clin Cancer Res. 2019. PMID: 30366937 Free PMC article.
CEST2022: Amide proton transfer-weighted MRI improves the diagnostic performance of multiparametric non-contrast-enhanced MRI techniques in patients with post-treatment high-grade gliomas.
Huang Q, Wu J, Le N, Shen Y, Guo P, Schreck KC, Kamson D, Blair L, Heo HY, Li X, Li W, Sair HL, Blakeley JO, Laterra J, Holdhoff M, Grossman SA, Mukherjee D, Bettegowda C, van Zijl P, Zhou J, Jiang S. Huang Q, et al. Among authors: blakeley jo. Magn Reson Imaging. 2023 Oct;102:222-228. doi: 10.1016/j.mri.2023.06.003. Epub 2023 Jun 14. Magn Reson Imaging. 2023. PMID: 37321378 Free PMC article.
215 results