An Z - Search Results

1

A novel therapeutic strategy to rescue the immune effector function of proteolytically inactivated cancer therapeutic antibodies.

Fan X, Brezski RJ, Deng H, Dhupkar PM, Shi Y, Gonzalez A, Zhang S, Rycyzyn M, Strohl WR, Jordan RE, Zhang N, An Z. Fan X, et al. Among authors: an z. Mol Cancer Ther. 2015 Mar;14(3):681-91. doi: 10.1158/1535-7163.MCT-14-0715. Epub 2014 Dec 31. Mol Cancer Ther. 2015. PMID: 25552368

2

Automated high-throughput purification of antibody fragments to facilitate evaluation in functional and kinetic based assays.

Su B, Hrin R, Harvey BR, Wang YJ, Ernst RE, Hampton RA, Miller MD, Strohl WR, An Z, Montgomery DL. Su B, et al. Among authors: an z. J Immunol Methods. 2007 Apr 30;322(1-2):94-103. doi: 10.1016/j.jim.2007.02.006. Epub 2007 Mar 7. J Immunol Methods. 2007. PMID: 17362979

3

Short communication: In vitro synergy between peptides or neutralizing antibodies targeting the N- and C-terminal heptad repeats of HIV Type 1 gp41.

Hrin R, Montgomery DL, Wang F, Condra JH, An Z, Strohl WR, Bianchi E, Pessi A, Joyce JG, Wang YJ. Hrin R, et al. Among authors: an z. AIDS Res Hum Retroviruses. 2008 Dec;24(12):1537-44. doi: 10.1089/aid.2008.0129. AIDS Res Hum Retroviruses. 2008. PMID: 19102685 Review.

4

IgG2m4, an engineered antibody isotype with reduced Fc function.

An Z, Forrest G, Moore R, Cukan M, Haytko P, Huang L, Vitelli S, Zhao JZ, Lu P, Hua J, Gibson CR, Harvey BR, Montgomery D, Zaller D, Wang F, Strohl W. An Z, et al. MAbs. 2009 Nov-Dec;1(6):572-9. doi: 10.4161/mabs.1.6.10185. MAbs. 2009. PMID: 20073128 Free PMC article.

5

Generation and selection of novel fully human monoclonal antibodies that neutralize Dickkopf-1 (DKK1) inhibitory function in vitro and increase bone mass in vivo.

Glantschnig H, Hampton RA, Lu P, Zhao JZ, Vitelli S, Huang L, Haytko P, Cusick T, Ireland C, Jarantow SW, Ernst R, Wei N, Nantermet P, Scott KR, Fisher JE, Talamo F, Orsatti L, Reszka AA, Sandhu P, Kimmel D, Flores O, Strohl W, An Z, Wang F. Glantschnig H, et al. Among authors: an z. J Biol Chem. 2010 Dec 17;285(51):40135-47. doi: 10.1074/jbc.M110.166892. Epub 2010 Oct 7. J Biol Chem. 2010. PMID: 20929859 Free PMC article.

6

A rate-limiting role for Dickkopf-1 in bone formation and the remediation of bone loss in mouse and primate models of postmenopausal osteoporosis by an experimental therapeutic antibody.

Glantschnig H, Scott K, Hampton R, Wei N, McCracken P, Nantermet P, Zhao JZ, Vitelli S, Huang L, Haytko P, Lu P, Fisher JE, Sandhu P, Cook J, Williams D, Strohl W, Flores O, Kimmel D, Wang F, An Z. Glantschnig H, et al. Among authors: an z. J Pharmacol Exp Ther. 2011 Aug;338(2):568-78. doi: 10.1124/jpet.111.181404. Epub 2011 Apr 29. J Pharmacol Exp Ther. 2011. PMID: 21531794

7

A single proteolytic cleavage within the lower hinge of trastuzumab reduces immune effector function and in vivo efficacy.

Fan X, Brezski RJ, Fa M, Deng H, Oberholtzer A, Gonzalez A, Dubinsky WP, Strohl WR, Jordan RE, Zhang N, An Z. Fan X, et al. Among authors: an z. Breast Cancer Res. 2012 Aug 8;14(4):R116. doi: 10.1186/bcr3240. Breast Cancer Res. 2012. PMID: 22873525 Free PMC article.

8

HER3 intracellular domains play a crucial role in HER3/HER2 dimerization and activation of downstream signaling pathways.

Choi BK, Cai X, Yuan B, Huang Z, Fan X, Deng H, Zhang N, An Z. Choi BK, et al. Among authors: an z. Protein Cell. 2012 Oct;3(10):781-9. doi: 10.1007/s13238-012-2065-y. Epub 2012 Sep 15. Protein Cell. 2012. PMID: 22983903 Free PMC article.

9

ERBB3 (HER3) is a key sensor in the regulation of ERBB-mediated signaling in both low and high ERBB2 (HER2) expressing cancer cells.

Choi BK, Fan X, Deng H, Zhang N, An Z. Choi BK, et al. Among authors: an z. Cancer Med. 2012 Aug;1(1):28-38. doi: 10.1002/cam4.10. Epub 2012 Jul 15. Cancer Med. 2012. PMID: 23342251 Free PMC article.

10

Human decellularized adipose tissue scaffold as a model for breast cancer cell growth and drug treatments.

Dunne LW, Huang Z, Meng W, Fan X, Zhang N, Zhang Q, An Z. Dunne LW, et al. Among authors: an z. Biomaterials. 2014 Jun;35(18):4940-9. doi: 10.1016/j.biomaterials.2014.03.003. Epub 2014 Mar 21. Biomaterials. 2014. PMID: 24661550

Save citations to file

Email citations

Send citations to clipboard

Add to Collections

Add to My Bibliography

Create a file for external citation management software

Your saved search

Your RSS Feed

My Custom Filters

Publication date

Text availability

Article attribute

Article type

Article Language

Species

Sex

Age

Other

2,140 results

Search Page

Filters