Flockhart DA - Search Results

1

Report of new haplotype for ABCC2 gene: rs17222723 and rs8187718 in cis.

Pratt VM, Beyer BN, Koller DL, Skaar TC, Flockhart DA, Levy KD, Vance GH. Pratt VM, et al. Among authors: flockhart da. J Mol Diagn. 2015 Mar;17(2):201-5. doi: 10.1016/j.jmoldx.2014.11.005. Epub 2014 Dec 29. J Mol Diagn. 2015. PMID: 25554586 Free PMC article.

2

FDA's draft guidance on laboratory-developed tests increases clinical and economic risk to adoption of pharmacogenetic testing.

Levy KD, Pratt VM, Skaar TC, Vance GH, Flockhart DA. Levy KD, et al. Among authors: flockhart da. J Clin Pharmacol. 2015 Jul;55(7):725-7. doi: 10.1002/jcph.492. J Clin Pharmacol. 2015. PMID: 26053647 Free PMC article. No abstract available.

3

Cypiripi: exact genotyping of CYP2D6 using high-throughput sequencing data.

Numanagić I, Malikić S, Pratt VM, Skaar TC, Flockhart DA, Sahinalp SC. Numanagić I, et al. Among authors: flockhart da. Bioinformatics. 2015 Jun 15;31(12):i27-34. doi: 10.1093/bioinformatics/btv232. Bioinformatics. 2015. PMID: 26072492 Free PMC article.

4

Functional characterization of a genetic polymorphism in the promoter of the ESR2 gene.

Philips S, Richter A, Oesterreich S, Rae JM, Flockhart DA, Perumal NB, Skaar TC. Philips S, et al. Among authors: flockhart da. Horm Cancer. 2012 Apr;3(1-2):37-43. doi: 10.1007/s12672-011-0086-2. Horm Cancer. 2012. PMID: 21979797 Free PMC article.

5

Analysis of angiogenesis genes from paraffin-embedded breast tumor and lymph nodes.

Schneider BP, Skaar TC, Sledge GW, Badve S, Li L, Flockhart DA. Schneider BP, et al. Among authors: flockhart da. Breast Cancer Res Treat. 2006 Apr;96(3):209-15. doi: 10.1007/s10549-005-9003-0. Epub 2006 Feb 28. Breast Cancer Res Treat. 2006. PMID: 16505966

6

Differential quantification of CYP2D6 gene copy number by four different quantitative real-time PCR assays.

Ramamoorthy A, Flockhart DA, Hosono N, Kubo M, Nakamura Y, Skaar TC. Ramamoorthy A, et al. Among authors: flockhart da. Pharmacogenet Genomics. 2010 Jul;20(7):451-4. doi: 10.1097/FPC.0b013e32833a1083. Pharmacogenet Genomics. 2010. PMID: 20421845 Free PMC article.

7

Design and synthesis of norendoxifen analogues with dual aromatase inhibitory and estrogen receptor modulatory activities.

Lv W, Liu J, Skaar TC, Flockhart DA, Cushman M. Lv W, et al. Among authors: flockhart da. J Med Chem. 2015 Mar 26;58(6):2623-48. doi: 10.1021/jm501218e. Epub 2015 Mar 9. J Med Chem. 2015. PMID: 25751283 Free PMC article.

8

Endoxifen (4-hydroxy-N-desmethyl-tamoxifen) has anti-estrogenic effects in breast cancer cells with potency similar to 4-hydroxy-tamoxifen.

Lim YC, Desta Z, Flockhart DA, Skaar TC. Lim YC, et al. Among authors: flockhart da. Cancer Chemother Pharmacol. 2005 May;55(5):471-8. doi: 10.1007/s00280-004-0926-7. Epub 2005 Feb 1. Cancer Chemother Pharmacol. 2005. PMID: 15685451

9

Endoxifen, a secondary metabolite of tamoxifen, and 4-OH-tamoxifen induce similar changes in global gene expression patterns in MCF-7 breast cancer cells.

Lim YC, Li L, Desta Z, Zhao Q, Rae JM, Flockhart DA, Skaar TC. Lim YC, et al. Among authors: flockhart da. J Pharmacol Exp Ther. 2006 Aug;318(2):503-12. doi: 10.1124/jpet.105.100511. Epub 2006 May 11. J Pharmacol Exp Ther. 2006. PMID: 16690721

10

Estrogen receptor genotypes influence hot flash prevalence and composite score before and after tamoxifen therapy.

Jin Y, Hayes DF, Li L, Robarge JD, Skaar TC, Philips S, Nguyen A, Schott A, Hayden J, Lemler S, Storniolo AM, Flockhart DA, Stearns V. Jin Y, et al. Among authors: flockhart da. J Clin Oncol. 2008 Dec 20;26(36):5849-54. doi: 10.1200/JCO.2008.16.8377. Epub 2008 Nov 17. J Clin Oncol. 2008. PMID: 19018086 Free PMC article.

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