Bosmans F - Search Results

1

The insecticidal spider toxin SFI1 is a knottin peptide that blocks the pore of insect voltage-gated sodium channels via a large β-hairpin loop.

Bende NS, Dziemborowicz S, Herzig V, Ramanujam V, Brown GW, Bosmans F, Nicholson GM, King GF, Mobli M. Bende NS, et al. Among authors: bosmans f. FEBS J. 2015 Mar;282(5):904-20. doi: 10.1111/febs.13189. Epub 2015 Jan 23. FEBS J. 2015. PMID: 25559770 Free article.

2

A distinct sodium channel voltage-sensor locus determines insect selectivity of the spider toxin Dc1a.

Bende NS, Dziemborowicz S, Mobli M, Herzig V, Gilchrist J, Wagner J, Nicholson GM, King GF, Bosmans F. Bende NS, et al. Among authors: bosmans f. Nat Commun. 2014 Jul 11;5:4350. doi: 10.1038/ncomms5350. Nat Commun. 2014. PMID: 25014760 Free PMC article.

3

Seven novel modulators of the analgesic target NaV 1.7 uncovered using a high-throughput venom-based discovery approach.

Klint JK, Smith JJ, Vetter I, Rupasinghe DB, Er SY, Senff S, Herzig V, Mobli M, Lewis RJ, Bosmans F, King GF. Klint JK, et al. Among authors: bosmans f. Br J Pharmacol. 2015 May;172(10):2445-58. doi: 10.1111/bph.13081. Epub 2015 Mar 4. Br J Pharmacol. 2015. PMID: 25754331 Free PMC article.

4

Molecular basis of the remarkable species selectivity of an insecticidal sodium channel toxin from the African spider Augacephalus ezendami.

Herzig V, Ikonomopoulou M, Smith JJ, Dziemborowicz S, Gilchrist J, Kuhn-Nentwig L, Rezende FO, Moreira LA, Nicholson GM, Bosmans F, King GF. Herzig V, et al. Among authors: bosmans f. Sci Rep. 2016 Jul 7;6:29538. doi: 10.1038/srep29538. Sci Rep. 2016. PMID: 27383378 Free PMC article.

5

Isolation of two insecticidal toxins from venom of the Australian theraphosid spider Coremiocnemis tropix.

Ikonomopoulou MP, Smith JJ, Herzig V, Pineda SS, Dziemborowicz S, Er SY, Durek T, Gilchrist J, Alewood PF, Nicholson GM, Bosmans F, King GF. Ikonomopoulou MP, et al. Among authors: bosmans f. Toxicon. 2016 Dec 1;123:62-70. doi: 10.1016/j.toxicon.2016.10.013. Epub 2016 Oct 26. Toxicon. 2016. PMID: 27793656 Free PMC article.

6

Insect-Active Toxins with Promiscuous Pharmacology from the African Theraphosid Spider Monocentropus balfouri.

Smith JJ, Herzig V, Ikonomopoulou MP, Dziemborowicz S, Bosmans F, Nicholson GM, King GF. Smith JJ, et al. Among authors: bosmans f. Toxins (Basel). 2017 May 5;9(5):155. doi: 10.3390/toxins9050155. Toxins (Basel). 2017. PMID: 28475112 Free PMC article.

7

The insecticidal neurotoxin Aps III is an atypical knottin peptide that potently blocks insect voltage-gated sodium channels.

Bende NS, Kang E, Herzig V, Bosmans F, Nicholson GM, Mobli M, King GF. Bende NS, et al. Among authors: bosmans f. Biochem Pharmacol. 2013 May 15;85(10):1542-54. doi: 10.1016/j.bcp.2013.02.030. Epub 2013 Mar 6. Biochem Pharmacol. 2013. PMID: 23473802 Free PMC article.

8

From foe to friend: using animal toxins to investigate ion channel function.

Kalia J, Milescu M, Salvatierra J, Wagner J, Klint JK, King GF, Olivera BM, Bosmans F. Kalia J, et al. Among authors: bosmans f. J Mol Biol. 2015 Jan 16;427(1):158-175. doi: 10.1016/j.jmb.2014.07.027. Epub 2014 Aug 1. J Mol Biol. 2015. PMID: 25088688 Free PMC article. Review.

9

Selective spider toxins reveal a role for the Nav1.1 channel in mechanical pain.

Osteen JD, Herzig V, Gilchrist J, Emrick JJ, Zhang C, Wang X, Castro J, Garcia-Caraballo S, Grundy L, Rychkov GY, Weyer AD, Dekan Z, Undheim EA, Alewood P, Stucky CL, Brierley SM, Basbaum AI, Bosmans F, King GF, Julius D. Osteen JD, et al. Among authors: bosmans f. Nature. 2016 Jun 23;534(7608):494-9. doi: 10.1038/nature17976. Epub 2016 Jun 6. Nature. 2016. PMID: 27281198 Free PMC article.

10

The tarantula toxin β/δ-TRTX-Pre1a highlights the importance of the S1-S2 voltage-sensor region for sodium channel subtype selectivity.

Wingerd JS, Mozar CA, Ussing CA, Murali SS, Chin YK, Cristofori-Armstrong B, Durek T, Gilchrist J, Vaughan CW, Bosmans F, Adams DJ, Lewis RJ, Alewood PF, Mobli M, Christie MJ, Rash LD. Wingerd JS, et al. Among authors: bosmans f. Sci Rep. 2017 Apr 20;7(1):974. doi: 10.1038/s41598-017-01129-0. Sci Rep. 2017. PMID: 28428547 Free PMC article.

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