Gellman SH - Search Results

1

Consequences of periodic α-to-β(3) residue replacement for immunological recognition of peptide epitopes.

Cheloha RW, Sullivan JA, Wang T, Sand JM, Sidney J, Sette A, Cook ME, Suresh M, Gellman SH. Cheloha RW, et al. Among authors: gellman sh. ACS Chem Biol. 2015 Mar 20;10(3):844-54. doi: 10.1021/cb500888q. Epub 2015 Jan 5. ACS Chem Biol. 2015. PMID: 25559929 Free PMC article.

2

Differential impact of β and γ residue preorganization on α/β/γ-peptide helix stability in water.

Shin YH, Mortenson DE, Satyshur KA, Forest KT, Gellman SH. Shin YH, et al. Among authors: gellman sh. J Am Chem Soc. 2013 Jun 5;135(22):8149-52. doi: 10.1021/ja403319q. Epub 2013 May 23. J Am Chem Soc. 2013. PMID: 23701135 Free PMC article.

3

Structure-guided rational design of α/β-peptide foldamers with high affinity for BCL-2 family prosurvival proteins.

Smith BJ, Lee EF, Checco JW, Evangelista M, Gellman SH, Fairlie WD. Smith BJ, et al. Among authors: gellman sh. Chembiochem. 2013 Sep 2;14(13):1564-72. doi: 10.1002/cbic.201300351. Epub 2013 Aug 8. Chembiochem. 2013. PMID: 23929624 Free PMC article.

4

Hydrophobicity and helicity regulate the antifungal activity of 14-helical β-peptides.

Lee MR, Raman N, Gellman SH, Lynn DM, Palecek SP. Lee MR, et al. Among authors: gellman sh. ACS Chem Biol. 2014 Jul 18;9(7):1613-21. doi: 10.1021/cb500203e. Epub 2014 Jun 2. ACS Chem Biol. 2014. PMID: 24837702 Free PMC article.

5

Backbone modification of a polypeptide drug alters duration of action in vivo.

Cheloha RW, Maeda A, Dean T, Gardella TJ, Gellman SH. Cheloha RW, et al. Among authors: gellman sh. Nat Biotechnol. 2014 Jul;32(7):653-5. doi: 10.1038/nbt.2920. Epub 2014 Jun 15. Nat Biotechnol. 2014. PMID: 24929976 Free PMC article.

6

A potent α/β-peptide analogue of GLP-1 with prolonged action in vivo.

Johnson LM, Barrick S, Hager MV, McFedries A, Homan EA, Rabaglia ME, Keller MP, Attie AD, Saghatelian A, Bisello A, Gellman SH. Johnson LM, et al. Among authors: gellman sh. J Am Chem Soc. 2014 Sep 17;136(37):12848-51. doi: 10.1021/ja507168t. Epub 2014 Sep 5. J Am Chem Soc. 2014. PMID: 25191938 Free PMC article.

7

Residue-Based Preorganization of BH3-Derived α/β-Peptides: Modulating Affinity, Selectivity and Proteolytic Susceptibility in α-Helix Mimics.

Peterson-Kaufman KJ, Haase HS, Boersma MD, Lee EF, Fairlie WD, Gellman SH. Peterson-Kaufman KJ, et al. Among authors: gellman sh. ACS Chem Biol. 2015 Jul 17;10(7):1667-75. doi: 10.1021/acschembio.5b00109. Epub 2015 May 7. ACS Chem Biol. 2015. PMID: 25946900 Free PMC article.

8

Heterogeneous H-bonding in a foldamer helix.

Fisher BF, Guo L, Dolinar BS, Guzei IA, Gellman SH. Fisher BF, et al. Among authors: gellman sh. J Am Chem Soc. 2015 May 27;137(20):6484-7. doi: 10.1021/jacs.5b03382. Epub 2015 May 14. J Am Chem Soc. 2015. PMID: 25974390 Free PMC article.

9

PTH receptor-1 signalling-mechanistic insights and therapeutic prospects.

Cheloha RW, Gellman SH, Vilardaga JP, Gardella TJ. Cheloha RW, et al. Among authors: gellman sh. Nat Rev Endocrinol. 2015 Dec;11(12):712-24. doi: 10.1038/nrendo.2015.139. Epub 2015 Aug 25. Nat Rev Endocrinol. 2015. PMID: 26303600 Free PMC article. Review.

10

α/β-Peptide Foldamers Targeting Intracellular Protein-Protein Interactions with Activity in Living Cells.

Checco JW, Lee EF, Evangelista M, Sleebs NJ, Rogers K, Pettikiriarachchi A, Kershaw NJ, Eddinger GA, Belair DG, Wilson JL, Eller CH, Raines RT, Murphy WL, Smith BJ, Gellman SH, Fairlie WD. Checco JW, et al. Among authors: gellman sh. J Am Chem Soc. 2015 Sep 9;137(35):11365-75. doi: 10.1021/jacs.5b05896. Epub 2015 Aug 28. J Am Chem Soc. 2015. PMID: 26317395 Free PMC article.

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