Doetsch PW - Search Results

1

Understanding cancer development processes after HZE-particle exposure: roles of ROS, DNA damage repair and inflammation.

Sridharan DM, Asaithamby A, Bailey SM, Costes SV, Doetsch PW, Dynan WS, Kronenberg A, Rithidech KN, Saha J, Snijders AM, Werner E, Wiese C, Cucinotta FA, Pluth JM. Sridharan DM, et al. Among authors: doetsch pw. Radiat Res. 2015 Jan;183(1):1-26. doi: 10.1667/RR13804.1. Epub 2015 Jan 7. Radiat Res. 2015. PMID: 25564719 Review.

2

Evaluating biomarkers to model cancer risk post cosmic ray exposure.

Sridharan DM, Asaithamby A, Blattnig SR, Costes SV, Doetsch PW, Dynan WS, Hahnfeldt P, Hlatky L, Kidane Y, Kronenberg A, Naidu MD, Peterson LE, Plante I, Ponomarev AL, Saha J, Snijders AM, Srinivasan K, Tang J, Werner E, Pluth JM. Sridharan DM, et al. Among authors: doetsch pw. Life Sci Space Res (Amst). 2016 Jun;9:19-47. doi: 10.1016/j.lssr.2016.05.004. Epub 2016 May 21. Life Sci Space Res (Amst). 2016. PMID: 27345199 Free PMC article. Review.

3

Role of Pro-inflammatory Cytokines in Radiation-Induced Genomic Instability in Human Bronchial Epithelial Cells.

Werner E, Wang H, Doetsch PW. Werner E, et al. Among authors: doetsch pw. Radiat Res. 2015 Dec;184(6):621-9. doi: 10.1667/RR14045.1. Epub 2015 Nov 18. Radiat Res. 2015. PMID: 26579942

4

A Single Exposure to Low- or High-LET Radiation Induces Persistent Genomic Damage in Mouse Epithelial Cells In Vitro and in Lung Tissue.

Werner E, Wang Y, Doetsch PW. Werner E, et al. Among authors: doetsch pw. Radiat Res. 2017 Oct;188(4):373-380. doi: 10.1667/RR14685.1. Epub 2017 Jul 28. Radiat Res. 2017. PMID: 28753066

5

Overexpression of the base excision repair NTHL1 glycosylase causes genomic instability and early cellular hallmarks of cancer.

Limpose KL, Trego KS, Li Z, Leung SW, Sarker AH, Shah JA, Ramalingam SS, Werner EM, Dynan WS, Cooper PK, Corbett AH, Doetsch PW. Limpose KL, et al. Among authors: doetsch pw. Nucleic Acids Res. 2018 May 18;46(9):4515-4532. doi: 10.1093/nar/gky162. Nucleic Acids Res. 2018. PMID: 29522130 Free PMC article.

6

Opposite roles for p38MAPK-driven responses and reactive oxygen species in the persistence and resolution of radiation-induced genomic instability.

Werner E, Wang H, Doetsch PW. Werner E, et al. Among authors: doetsch pw. PLoS One. 2014 Oct 1;9(10):e108234. doi: 10.1371/journal.pone.0108234. eCollection 2014. PLoS One. 2014. PMID: 25271419 Free PMC article.

7

Distinct roles of Ape1 protein, an enzyme involved in DNA repair, in high or low linear energy transfer ionizing radiation-induced cell killing.

Wang H, Wang X, Chen G, Zhang X, Tang X, Park D, Cucinotta FA, Yu DS, Deng X, Dynan WS, Doetsch PW, Wang Y. Wang H, et al. Among authors: doetsch pw. J Biol Chem. 2014 Oct 31;289(44):30635-30644. doi: 10.1074/jbc.M114.604959. Epub 2014 Sep 10. J Biol Chem. 2014. Retraction in: J Biol Chem. 2020 May 1;295(18):6249. doi: 10.1074/jbc.W120.013724 PMID: 25210033 Free PMC article. Retracted.

8

HPV16 E6 and E7 proteins induce a chronic oxidative stress response via NOX2 that causes genomic instability and increased susceptibility to DNA damage in head and neck cancer cells.

Marullo R, Werner E, Zhang H, Chen GZ, Shin DM, Doetsch PW. Marullo R, et al. Among authors: doetsch pw. Carcinogenesis. 2015 Nov;36(11):1397-406. doi: 10.1093/carcin/bgv126. Epub 2015 Sep 8. Carcinogenesis. 2015. PMID: 26354779 Free PMC article.

9

Cisplatin induces a mitochondrial-ROS response that contributes to cytotoxicity depending on mitochondrial redox status and bioenergetic functions.

Marullo R, Werner E, Degtyareva N, Moore B, Altavilla G, Ramalingam SS, Doetsch PW. Marullo R, et al. Among authors: doetsch pw. PLoS One. 2013 Nov 19;8(11):e81162. doi: 10.1371/journal.pone.0081162. eCollection 2013. PLoS One. 2013. PMID: 24260552 Free PMC article.

10

MicroRNA-21 modulates the levels of reactive oxygen species by targeting SOD3 and TNFα.

Zhang X, Ng WL, Wang P, Tian L, Werner E, Wang H, Doetsch P, Wang Y. Zhang X, et al. Cancer Res. 2012 Sep 15;72(18):4707-13. doi: 10.1158/0008-5472.CAN-12-0639. Epub 2012 Jul 25. Cancer Res. 2012. PMID: 22836756 Free PMC article.

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