Langford-Smith A - Search Results

1

Neuroinflammation, mitochondrial defects and neurodegeneration in mucopolysaccharidosis III type C mouse model.

Martins C, Hůlková H, Dridi L, Dormoy-Raclet V, Grigoryeva L, Choi Y, Langford-Smith A, Wilkinson FL, Ohmi K, DiCristo G, Hamel E, Ausseil J, Cheillan D, Moreau A, Svobodová E, Hájková Z, Tesařová M, Hansíková H, Bigger BW, Hrebícek M, Pshezhetsky AV. Martins C, et al. Brain. 2015 Feb;138(Pt 2):336-55. doi: 10.1093/brain/awu355. Epub 2015 Jan 6. Brain. 2015. PMID: 25567323 Free PMC article.

2

Hematopoietic stem cell and gene therapy corrects primary neuropathology and behavior in mucopolysaccharidosis IIIA mice.

Langford-Smith A, Wilkinson FL, Langford-Smith KJ, Holley RJ, Sergijenko A, Howe SJ, Bennett WR, Jones SA, Wraith J, Merry CL, Wynn RF, Bigger BW. Langford-Smith A, et al. Mol Ther. 2012 Aug;20(8):1610-21. doi: 10.1038/mt.2012.82. Epub 2012 May 1. Mol Ther. 2012. PMID: 22547151 Free PMC article.

3

Female mucopolysaccharidosis IIIA mice exhibit hyperactivity and a reduced sense of danger in the open field test.

Langford-Smith A, Langford-Smith KJ, Jones SA, Wynn RF, Wraith JE, Wilkinson FL, Bigger BW. Langford-Smith A, et al. PLoS One. 2011;6(10):e25717. doi: 10.1371/journal.pone.0025717. Epub 2011 Oct 18. PLoS One. 2011. PMID: 22028789 Free PMC article.

4

Neuropathology in mouse models of mucopolysaccharidosis type I, IIIA and IIIB.

Wilkinson FL, Holley RJ, Langford-Smith KJ, Badrinath S, Liao A, Langford-Smith A, Cooper JD, Jones SA, Wraith JE, Wynn RF, Merry CL, Bigger BW. Wilkinson FL, et al. PLoS One. 2012;7(4):e35787. doi: 10.1371/journal.pone.0035787. Epub 2012 Apr 27. PLoS One. 2012. PMID: 22558223 Free PMC article.

5

Myeloid/Microglial driven autologous hematopoietic stem cell gene therapy corrects a neuronopathic lysosomal disease.

Sergijenko A, Langford-Smith A, Liao AY, Pickford CE, McDermott J, Nowinski G, Langford-Smith KJ, Merry CL, Jones SA, Wraith JE, Wynn RF, Wilkinson FL, Bigger BW. Sergijenko A, et al. Mol Ther. 2013 Oct;21(10):1938-49. doi: 10.1038/mt.2013.141. Epub 2013 Jun 7. Mol Ther. 2013. PMID: 23748415 Free PMC article.

6

Genistein improves neuropathology and corrects behaviour in a mouse model of neurodegenerative metabolic disease.

Malinowska M, Wilkinson FL, Langford-Smith KJ, Langford-Smith A, Brown JR, Crawford BE, Vanier MT, Grynkiewicz G, Wynn RF, Wraith JE, Wegrzyn G, Bigger BW. Malinowska M, et al. PLoS One. 2010 Dec 1;5(12):e14192. doi: 10.1371/journal.pone.0014192. PLoS One. 2010. PMID: 21152017 Free PMC article.

7

Signal one and two blockade are both critical for non-myeloablative murine HSCT across a major histocompatibility complex barrier.

Langford-Smith KJ, Sandiford Z, Langford-Smith A, Wilkinson FL, Jones SA, Wraith JE, Wynn RF, Bigger BW. Langford-Smith KJ, et al. PLoS One. 2013 Oct 17;8(10):e77632. doi: 10.1371/journal.pone.0077632. eCollection 2013. PLoS One. 2013. PMID: 24147041 Free PMC article.

8

Endothelial microparticles prevent lipid-induced endothelial damage via Akt/eNOS signaling and reduced oxidative stress.

Mahmoud AM, Wilkinson FL, McCarthy EM, Moreno-Martinez D, Langford-Smith A, Romero M, Duarte J, Alexander MY. Mahmoud AM, et al. Among authors: langford smith a. FASEB J. 2017 Oct;31(10):4636-4648. doi: 10.1096/fj.201601244RR. Epub 2017 Jul 7. FASEB J. 2017. PMID: 28687612 Free PMC article.

9

The role of complement in age-related macular degeneration: heparan sulphate, a ZIP code for complement factor H?

Langford-Smith A, Keenan TD, Clark SJ, Bishop PN, Day AJ. Langford-Smith A, et al. J Innate Immun. 2014;6(4):407-16. doi: 10.1159/000356513. Epub 2013 Dec 7. J Innate Immun. 2014. PMID: 24335201 Free PMC article. Review.

10

Age and Smoking Related Changes in Metal Ion Levels in Human Lens: Implications for Cataract Formation.

Langford-Smith A, Tilakaratna V, Lythgoe PR, Clark SJ, Bishop PN, Day AJ. Langford-Smith A, et al. PLoS One. 2016 Jan 21;11(1):e0147576. doi: 10.1371/journal.pone.0147576. eCollection 2016. PLoS One. 2016. PMID: 26794210 Free PMC article.

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