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Reversal of autoimmune diabetes by restoration of antigen-specific tolerance using genetically modified Lactococcus lactis in mice.
Takiishi T, Korf H, Van Belle TL, Robert S, Grieco FA, Caluwaerts S, Galleri L, Spagnuolo I, Steidler L, Van Huynegem K, Demetter P, Wasserfall C, Atkinson MA, Dotta F, Rottiers P, Gysemans C, Mathieu C. Takiishi T, et al. Among authors: steidler l. J Clin Invest. 2012 May;122(5):1717-25. doi: 10.1172/JCI60530. Epub 2012 Apr 9. J Clin Invest. 2012. PMID: 22484814 Free PMC article.
Oral delivery of glutamic acid decarboxylase (GAD)-65 and IL10 by Lactococcus lactis reverses diabetes in recent-onset NOD mice.
Robert S, Gysemans C, Takiishi T, Korf H, Spagnuolo I, Sebastiani G, Van Huynegem K, Steidler L, Caluwaerts S, Demetter P, Wasserfall CH, Atkinson MA, Dotta F, Rottiers P, Van Belle TL, Mathieu C. Robert S, et al. Among authors: steidler l. Diabetes. 2014 Aug;63(8):2876-87. doi: 10.2337/db13-1236. Epub 2014 Mar 27. Diabetes. 2014. PMID: 24677716 Free article.
Reversal of Diabetes in NOD Mice by Clinical-Grade Proinsulin and IL-10-Secreting Lactococcus lactis in Combination With Low-Dose Anti-CD3 Depends on the Induction of Foxp3-Positive T Cells.
Takiishi T, Cook DP, Korf H, Sebastiani G, Mancarella F, Cunha JP, Wasserfall C, Casares N, Lasarte JJ, Steidler L, Rottiers P, Dotta F, Gysemans C, Mathieu C. Takiishi T, et al. Among authors: steidler l. Diabetes. 2017 Feb;66(2):448-459. doi: 10.2337/db15-1625. Epub 2016 Nov 8. Diabetes. 2017. PMID: 28108611
Intestinal Delivery of Proinsulin and IL-10 via Lactococcus lactis Combined With Low-Dose Anti-CD3 Restores Tolerance Outside the Window of Acute Type 1 Diabetes Diagnosis.
Cook DP, Cunha JPMCM, Martens PJ, Sassi G, Mancarella F, Ventriglia G, Sebastiani G, Vanherwegen AS, Atkinson MA, Van Huynegem K, Steidler L, Caluwaerts S, Rottiers P, Teyton L, Dotta F, Gysemans C, Mathieu C. Cook DP, et al. Among authors: steidler l. Front Immunol. 2020 Jun 9;11:1103. doi: 10.3389/fimmu.2020.01103. eCollection 2020. Front Immunol. 2020. PMID: 32582188 Free PMC article.
Immunomodulation by genetically engineered lactic acid bacteria.
Van Huynegem K, Loos M, Steidler L. Van Huynegem K, et al. Among authors: steidler l. Front Biosci (Landmark Ed). 2009 Jun 1;14(13):4825-35. doi: 10.2741/3571. Front Biosci (Landmark Ed). 2009. PMID: 19482589 Free article. Review.
52 results