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Bioisosteric analogs of MDMA with improved pharmacological profile.
Alberto-Silva AS, Hemmer S, Bock HA, Alves da Silva L, Scott KR, Kastner N, Bhatt M, Niello M, Jäntsch K, Kudlacek O, Bossi E, Stockner T, Meyer MR, McCorvy JD, Brandt SD, Kavanagh P, Sitte HH. Alberto-Silva AS, et al. Among authors: mccorvy jd. bioRxiv [Preprint]. 2024 Apr 11:2024.04.08.588083. doi: 10.1101/2024.04.08.588083. bioRxiv. 2024. Update in: J Neurochem. 2024 Sep;168(9):2022-2042. doi: 10.1111/jnc.16149 PMID: 38645142 Free PMC article. Updated. Preprint.
DPP4-Truncated CXCL12 Alters CXCR4/ACKR3 Signaling, Osteogenic Cell Differentiation, Migration, and Senescence.
Elmansi AM, Eisa NH, Periyasamy-Thandavan S, Kondrikova G, Kondrikov D, Calkins MM, Aguilar-Pérez A, Chen J, Johnson M, Shi XM, Reitman C, McGee-Lawrence ME, Crawford KS, Dwinell MB, Volkman BF, Blumer JB, Luttrell LM, McCorvy JD, Hill WD. Elmansi AM, et al. Among authors: mccorvy jd. ACS Pharmacol Transl Sci. 2022 Dec 13;6(1):22-39. doi: 10.1021/acsptsci.2c00040. eCollection 2023 Jan 13. ACS Pharmacol Transl Sci. 2022. PMID: 36659961 Free PMC article.
Further Advances in Optimizing (2-Phenylcyclopropyl)methylamines as Novel Serotonin 2C Agonists: Effects on Hyperlocomotion, Prepulse Inhibition, and Cognition Models.
Cheng J, Giguere PM, Schmerberg CM, Pogorelov VM, Rodriguiz RM, Huang XP, Zhu H, McCorvy JD, Wetsel WC, Roth BL, Kozikowski AP. Cheng J, et al. Among authors: mccorvy jd. J Med Chem. 2016 Jan 28;59(2):578-91. doi: 10.1021/acs.jmedchem.5b01153. Epub 2016 Jan 13. J Med Chem. 2016. PMID: 26704965 Free PMC article.
Discovery of G Protein-Biased D2 Dopamine Receptor Partial Agonists.
Chen X, McCorvy JD, Fischer MG, Butler KV, Shen Y, Roth BL, Jin J. Chen X, et al. Among authors: mccorvy jd. J Med Chem. 2016 Dec 8;59(23):10601-10618. doi: 10.1021/acs.jmedchem.6b01208. Epub 2016 Nov 16. J Med Chem. 2016. PMID: 27805392 Free PMC article.
79 results