Linington RG - Search Results

1

Salinipostins A-K, long-chain bicyclic phosphotriesters as a potent and selective antimalarial chemotype.

Schulze CJ, Navarro G, Ebert D, DeRisi J, Linington RG. Schulze CJ, et al. Among authors: linington rg. J Org Chem. 2015 Feb 6;80(3):1312-20. doi: 10.1021/jo5024409. Epub 2015 Jan 13. J Org Chem. 2015. PMID: 25584395

2

Almiramides A-C: discovery and development of a new class of leishmaniasis lead compounds.

Sanchez LM, Lopez D, Vesely BA, Della Togna G, Gerwick WH, Kyle DE, Linington RG. Sanchez LM, et al. Among authors: linington rg. J Med Chem. 2010 May 27;53(10):4187-97. doi: 10.1021/jm100265s. J Med Chem. 2010. PMID: 20441198 Free PMC article.

3

New innovations for an old infection: antimalarial lead discovery from marine natural products during the period 2003-2008.

Peach KC, Linington RG. Peach KC, et al. Among authors: linington rg. Future Med Chem. 2009 Jul;1(4):593-617. doi: 10.4155/fmc.09.56. Future Med Chem. 2009. PMID: 21426029 Review.

4

Versatile method for the detection of covalently bound substrates on solid supports by DART mass spectrometry.

Sanchez LM, Curtis ME, Bracamonte BE, Kurita KL, Navarro G, Sparkman OD, Linington RG. Sanchez LM, et al. Among authors: linington rg. Org Lett. 2011 Aug 5;13(15):3770-3. doi: 10.1021/ol201404v. Epub 2011 Jun 24. Org Lett. 2011. PMID: 21699263 Free PMC article.

5

Highlights of marine invertebrate-derived biosynthetic products: their biomedical potential and possible production by microbial associants.

Radjasa OK, Vaske YM, Navarro G, Vervoort HC, Tenney K, Linington RG, Crews P. Radjasa OK, et al. Among authors: linington rg. Bioorg Med Chem. 2011 Nov 15;19(22):6658-74. doi: 10.1016/j.bmc.2011.07.017. Epub 2011 Jul 26. Bioorg Med Chem. 2011. PMID: 21835627 Free PMC article. Review.

6

Examining the fish microbiome: vertebrate-derived bacteria as an environmental niche for the discovery of unique marine natural products.

Sanchez LM, Wong WR, Riener RM, Schulze CJ, Linington RG. Sanchez LM, et al. Among authors: linington rg. PLoS One. 2012;7(5):e35398. doi: 10.1371/journal.pone.0035398. Epub 2012 May 4. PLoS One. 2012. PMID: 22574119 Free PMC article.

7

Hit-to-lead development of the chamigrane endoperoxide merulin A for the treatment of African sleeping sickness.

Navarro G, Chokpaiboon S, De Muylder G, Bray WM, Nisam SC, McKerrow JH, Pudhom K, Linington RG. Navarro G, et al. Among authors: linington rg. PLoS One. 2012;7(9):e46172. doi: 10.1371/journal.pone.0046172. Epub 2012 Sep 27. PLoS One. 2012. PMID: 23029428 Free PMC article.

8

"Function-first" lead discovery: mode of action profiling of natural product libraries using image-based screening.

Schulze CJ, Bray WM, Woerhmann MH, Stuart J, Lokey RS, Linington RG. Schulze CJ, et al. Among authors: linington rg. Chem Biol. 2013 Feb 21;20(2):285-95. doi: 10.1016/j.chembiol.2012.12.007. Chem Biol. 2013. PMID: 23438757 Free PMC article.

9

Image-based 384-well high-throughput screening method for the discovery of skyllamycins A to C as biofilm inhibitors and inducers of biofilm detachment in Pseudomonas aeruginosa.

Navarro G, Cheng AT, Peach KC, Bray WM, Bernan VS, Yildiz FH, Linington RG. Navarro G, et al. Among authors: linington rg. Antimicrob Agents Chemother. 2014;58(2):1092-9. doi: 10.1128/AAC.01781-13. Epub 2013 Dec 2. Antimicrob Agents Chemother. 2014. PMID: 24295976 Free PMC article.

10

A systematic analysis of biosynthetic gene clusters in the human microbiome reveals a common family of antibiotics.

Donia MS, Cimermancic P, Schulze CJ, Wieland Brown LC, Martin J, Mitreva M, Clardy J, Linington RG, Fischbach MA. Donia MS, et al. Among authors: linington rg. Cell. 2014 Sep 11;158(6):1402-1414. doi: 10.1016/j.cell.2014.08.032. Cell. 2014. PMID: 25215495 Free PMC article.

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