Shain K - Search Results

1

An open-label phase I/II study of cyclophosphamide, bortezomib, pegylated liposomal doxorubicin, and dexamethasone in newly diagnosed myeloma.

Nishihori T, Baz R, Shain K, Kim J, Ochoa-Bayona JL, Yue B, Sullivan D, Dalton W, Alsina M. Nishihori T, et al. Among authors: shain k. Eur J Haematol. 2015 Nov;95(5):426-35. doi: 10.1111/ejh.12509. Epub 2015 Mar 12. Eur J Haematol. 2015. PMID: 25600676 Free PMC article. Clinical Trial.

2

Myeloma cells selected for resistance to CD95-mediated apoptosis are not cross-resistant to cytotoxic drugs: evidence for independent mechanisms of caspase activation.

Landowski TH, Shain KH, Oshiro MM, Buyuksal I, Painter JS, Dalton WS. Landowski TH, et al. Among authors: shain kh. Blood. 1999 Jul 1;94(1):265-74. Blood. 1999. PMID: 10381522 Free article.

3

Clonal variability in CD95 expression is the major determinant in Fas-medicated, but not chemotherapy-medicated apoptosis in the RPMI 8226 multiple myeloma cell line.

Shain KH, Landowski TH, Buyuksal I, Cantor AB, Dalton WS. Shain KH, et al. Leukemia. 2000 May;14(5):830-40. doi: 10.1038/sj.leu.2401776. Leukemia. 2000. PMID: 10803514

4

The tumor microenvironment as a determinant of cancer cell survival: a possible mechanism for de novo drug resistance.

Shain KH, Landowski TH, Dalton WS. Shain KH, et al. Curr Opin Oncol. 2000 Nov;12(6):557-63. doi: 10.1097/00001622-200011000-00008. Curr Opin Oncol. 2000. PMID: 11085455 Review.

5

Overexpression of a dominant-negative signal transducer and activator of transcription 3 variant in tumor cells leads to production of soluble factors that induce apoptosis and cell cycle arrest.

Niu G, Shain KH, Huang M, Ravi R, Bedi A, Dalton WS, Jove R, Yu H. Niu G, et al. Among authors: shain kh. Cancer Res. 2001 Apr 15;61(8):3276-80. Cancer Res. 2001. PMID: 11309279

6

Adhesion-mediated intracellular redistribution of c-Fas-associated death domain-like IL-1-converting enzyme-like inhibitory protein-long confers resistance to CD95-induced apoptosis in hematopoietic cancer cell lines.

Shain KH, Landowski TH, Dalton WS. Shain KH, et al. J Immunol. 2002 Mar 1;168(5):2544-53. doi: 10.4049/jimmunol.168.5.2544. J Immunol. 2002. PMID: 11859150

7

Cell adhesion is a key determinant in de novo multidrug resistance (MDR): new targets for the prevention of acquired MDR.

Shain KH, Dalton WS. Shain KH, et al. Mol Cancer Ther. 2001 Nov;1(1):69-78. Mol Cancer Ther. 2001. PMID: 12467240 Review.

8

Genotypic and phenotypic comparisons of de novo and acquired melphalan resistance in an isogenic multiple myeloma cell line model.

Hazlehurst LA, Enkemann SA, Beam CA, Argilagos RF, Painter J, Shain KH, Saporta S, Boulware D, Moscinski L, Alsina M, Dalton WS. Hazlehurst LA, et al. Cancer Res. 2003 Nov 15;63(22):7900-6. Cancer Res. 2003. PMID: 14633719

9

Targeting the bone marrow microenvironment in hematologic malignancies.

Dalton WS, Hazlehurst L, Shain K, Landowski T, Alsina M. Dalton WS, et al. Among authors: shain k. Semin Hematol. 2004 Apr;41(2 Suppl 4):1-5. doi: 10.1053/j.seminhematol.2004.02.001. Semin Hematol. 2004. PMID: 15190509 Review.

10

Stat3 activity in melanoma cells affects migration of immune effector cells and nitric oxide-mediated antitumor effects.

Burdelya L, Kujawski M, Niu G, Zhong B, Wang T, Zhang S, Kortylewski M, Shain K, Kay H, Djeu J, Dalton W, Pardoll D, Wei S, Yu H. Burdelya L, et al. Among authors: shain k. J Immunol. 2005 Apr 1;174(7):3925-31. doi: 10.4049/jimmunol.174.7.3925. J Immunol. 2005. PMID: 15778348 Free PMC article.

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