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Eravacycline (TP-434) is efficacious in animal models of infection.
Grossman TH, Murphy TM, Slee AM, Lofland D, Sutcliffe JA. Grossman TH, et al. Antimicrob Agents Chemother. 2015 May;59(5):2567-71. doi: 10.1128/AAC.04354-14. Epub 2015 Feb 17. Antimicrob Agents Chemother. 2015. PMID: 25691636 Free PMC article.
The Fluorocycline TP-271 Is Efficacious in Models of Aerosolized Francisella tularensis SCHU S4 Infection in BALB/c Mice and Cynomolgus Macaques.
Grossman TH, Anderson MS, Christ D, Gooldy M, Henning LN, Heine HS, Kindt MV, Lin W, Siefkas-Patterson K, Radcliff AK, Tam VH, Sutcliffe JA. Grossman TH, et al. Antimicrob Agents Chemother. 2017 Jul 25;61(8):e00448-17. doi: 10.1128/AAC.00448-17. Print 2017 Aug. Antimicrob Agents Chemother. 2017. PMID: 28559261 Free PMC article.
The Fluorocycline TP-271 Is Efficacious in Models of Aerosolized Bacillus anthracis Infection in BALB/c Mice and Cynomolgus Macaques.
Grossman TH, Anderson MS, Drabek L, Gooldy M, Heine HS, Henning LN, Lin W, Newman JV, Nevarez R, Siefkas-Patterson K, Radcliff AK, Sutcliffe JA. Grossman TH, et al. Antimicrob Agents Chemother. 2017 Sep 22;61(10):e01103-17. doi: 10.1128/AAC.01103-17. Print 2017 Oct. Antimicrob Agents Chemother. 2017. PMID: 28784679 Free PMC article.
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