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Mouse granzyme K has pro-inflammatory potential.
Joeckel LT, Wallich R, Martin P, Sanchez-Martinez D, Weber FC, Martin SF, Borner C, Pardo J, Froelich C, Simon MM. Joeckel LT, et al. Cell Death Differ. 2011 Jul;18(7):1112-9. doi: 10.1038/cdd.2011.5. Epub 2011 Feb 11. Cell Death Differ. 2011. PMID: 21311565 Free PMC article.
Human and mouse granzyme A induce a proinflammatory cytokine response.
Metkar SS, Menaa C, Pardo J, Wang B, Wallich R, Freudenberg M, Kim S, Raja SM, Shi L, Simon MM, Froelich CJ. Metkar SS, et al. Among authors: froelich cj. Immunity. 2008 Nov 14;29(5):720-33. doi: 10.1016/j.immuni.2008.08.014. Epub 2008 Oct 23. Immunity. 2008. PMID: 18951048 Free article.
Perforin rapidly induces plasma membrane phospholipid flip-flop.
Metkar SS, Wang B, Catalan E, Anderluh G, Gilbert RJ, Pardo J, Froelich CJ. Metkar SS, et al. Among authors: froelich cj. PLoS One. 2011;6(9):e24286. doi: 10.1371/journal.pone.0024286. Epub 2011 Sep 12. PLoS One. 2011. PMID: 21931672 Free PMC article.
Granzyme A Contributes to Inflammatory Arthritis in Mice Through Stimulation of Osteoclastogenesis.
Santiago L, Menaa C, Arias M, Martin P, Jaime-Sánchez P, Metkar S, Comas L, Erill N, Gonzalez-Rumayor V, Esser E, Galvez EM, Raja S, Simon MM, Sprague SM, Gabay C, Martinez-Lostao L, Pardo J, Froelich CJ. Santiago L, et al. Among authors: froelich cj. Arthritis Rheumatol. 2017 Feb;69(2):320-334. doi: 10.1002/art.39857. Arthritis Rheumatol. 2017. PMID: 27598995
Granzyme A is a proinflammatory protease.
Pardo J, Simon MM, Froelich CJ. Pardo J, et al. Among authors: froelich cj. Blood. 2009 Oct 29;114(18):3968; author reply 3969-70. doi: 10.1182/blood-2009-07-231027. Blood. 2009. PMID: 19875524 Free article. No abstract available.
125 results