Lin G - Search Results

1

Stressed mycobacteria use the chaperone ClpB to sequester irreversibly oxidized proteins asymmetrically within and between cells.

Vaubourgeix J, Lin G, Dhar N, Chenouard N, Jiang X, Botella H, Lupoli T, Mariani O, Yang G, Ouerfelli O, Unser M, Schnappinger D, McKinney J, Nathan C. Vaubourgeix J, et al. Among authors: lin g. Cell Host Microbe. 2015 Feb 11;17(2):178-90. doi: 10.1016/j.chom.2014.12.008. Epub 2015 Jan 22. Cell Host Microbe. 2015. PMID: 25620549 Free PMC article.

2

Characterization of a Mycobacterium tuberculosis proteasomal ATPase homologue.

Darwin KH, Lin G, Chen Z, Li H, Nathan CF. Darwin KH, et al. Among authors: lin g. Mol Microbiol. 2005 Jan;55(2):561-71. doi: 10.1111/j.1365-2958.2004.04403.x. Mol Microbiol. 2005. PMID: 15659170 Free article.

3

Mycobacterium tuberculosis prcBA genes encode a gated proteasome with broad oligopeptide specificity.

Lin G, Hu G, Tsu C, Kunes YZ, Li H, Dick L, Parsons T, Li P, Chen Z, Zwickl P, Weich N, Nathan C. Lin G, et al. Mol Microbiol. 2006 Mar;59(5):1405-16. doi: 10.1111/j.1365-2958.2005.05035.x. Mol Microbiol. 2006. PMID: 16468985 Free article.

4

Structure of the Mycobacterium tuberculosis proteasome and mechanism of inhibition by a peptidyl boronate.

Hu G, Lin G, Wang M, Dick L, Xu RM, Nathan C, Li H. Hu G, et al. Among authors: lin g. Mol Microbiol. 2006 Mar;59(5):1417-28. doi: 10.1111/j.1365-2958.2005.05036.x. Mol Microbiol. 2006. PMID: 16468986 Free article.

5

Selective killing of nonreplicating mycobacteria.

Bryk R, Gold B, Venugopal A, Singh J, Samy R, Pupek K, Cao H, Popescu C, Gurney M, Hotha S, Cherian J, Rhee K, Ly L, Converse PJ, Ehrt S, Vandal O, Jiang X, Schneider J, Lin G, Nathan C. Bryk R, et al. Among authors: lin g. Cell Host Microbe. 2008 Mar 13;3(3):137-45. doi: 10.1016/j.chom.2008.02.003. Cell Host Microbe. 2008. PMID: 18329613 Free PMC article.

6

A philosophy of anti-infectives as a guide in the search for new drugs for tuberculosis.

Nathan C, Gold B, Lin G, Stegman M, de Carvalho LP, Vandal O, Venugopal A, Bryk R. Nathan C, et al. Among authors: lin g. Tuberculosis (Edinb). 2008 Aug;88 Suppl 1:S25-33. doi: 10.1016/S1472-9792(08)70034-9. Tuberculosis (Edinb). 2008. PMID: 18762150 Review.

7

Distinct specificities of Mycobacterium tuberculosis and mammalian proteasomes for N-acetyl tripeptide substrates.

Lin G, Tsu C, Dick L, Zhou XK, Nathan C. Lin G, et al. J Biol Chem. 2008 Dec 5;283(49):34423-31. doi: 10.1074/jbc.M805324200. Epub 2008 Oct 1. J Biol Chem. 2008. PMID: 18829465 Free PMC article.

8

Nitazoxanide kills replicating and nonreplicating Mycobacterium tuberculosis and evades resistance.

de Carvalho LP, Lin G, Jiang X, Nathan C. de Carvalho LP, et al. Among authors: lin g. J Med Chem. 2009 Oct 8;52(19):5789-92. doi: 10.1021/jm9010719. J Med Chem. 2009. PMID: 19736929

9

Inhibitors selective for mycobacterial versus human proteasomes.

Lin G, Li D, de Carvalho LP, Deng H, Tao H, Vogt G, Wu K, Schneider J, Chidawanyika T, Warren JD, Li H, Nathan C. Lin G, et al. Nature. 2009 Oct 1;461(7264):621-6. doi: 10.1038/nature08357. Epub 2009 Sep 16. Nature. 2009. PMID: 19759536 Free PMC article.

10

Structural insights on the Mycobacterium tuberculosis proteasomal ATPase Mpa.

Wang T, Li H, Lin G, Tang C, Li D, Nathan C, Darwin KH, Li H. Wang T, et al. Among authors: lin g. Structure. 2009 Oct 14;17(10):1377-85. doi: 10.1016/j.str.2009.08.010. Structure. 2009. PMID: 19836337 Free PMC article.

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