Huang B - Search Results

1

Synthesis and Biological Evaluation of a Series of 2-((1-substituted-1H-1,2,3-triazol-4-yl)methylthio)-6-(naphthalen-1-ylmethyl)pyrimidin-4(3H)-one As Potential HIV-1 Inhibitors.

Fang Z, Kang D, Zhang L, Huang B, Liu H, Pannecouque C, De Clercq E, Zhan P, Liu X. Fang Z, et al. Among authors: huang b. Chem Biol Drug Des. 2015 Oct;86(4):614-8. doi: 10.1111/cbdd.12524. Epub 2015 Feb 19. Chem Biol Drug Des. 2015. PMID: 25626467

2

Discovery of small molecular inhibitors targeting HIV-1 gp120-CD4 interaction drived from BMS-378806.

Liu T, Huang B, Zhan P, De Clercq E, Liu X. Liu T, et al. Among authors: huang b. Eur J Med Chem. 2014 Oct 30;86:481-90. doi: 10.1016/j.ejmech.2014.09.012. Epub 2014 Sep 6. Eur J Med Chem. 2014. PMID: 25203778 Review.

3

Design, Synthesis, and Biological Evaluation of Novel 4-Aminopiperidinyl-linked 3,5-Disubstituted-1,2,6-thiadiazine-1,1-dione Derivatives as HIV-1 NNRTIs.

Liu T, Huang B, Tian Y, Liang X, Liu H, Liu H, Zhan P, De Clercq E, Pannecouque C, Liu X. Liu T, et al. Among authors: huang b. Chem Biol Drug Des. 2015 Jul;86(1):107-13. doi: 10.1111/cbdd.12468. Epub 2014 Dec 5. Chem Biol Drug Des. 2015. PMID: 25359703

4

Synthesis and Preliminary Antiviral Activities of Piperidine-substituted Purines against HIV and Influenza A/H1N1 Infections.

Kang D, Fang Z, Huang B, Zhang L, Liu H, Pannecouque C, Naesens L, De Clercq E, Zhan P, Liu X. Kang D, et al. Among authors: huang b. Chem Biol Drug Des. 2015 Oct;86(4):568-77. doi: 10.1111/cbdd.12520. Epub 2015 Feb 6. Chem Biol Drug Des. 2015. PMID: 25600073

5

Fused heterocycles bearing bridgehead nitrogen as potent HIV-1 NNRTIs. Part 3: optimization of [1,2,4]triazolo[1,5-a]pyrimidine core via structure-based and physicochemical property-driven approaches.

Huang B, Li C, Chen W, Liu T, Yu M, Fu L, Sun Y, Liu H, De Clercq E, Pannecouque C, Balzarini J, Zhan P, Liu X. Huang B, et al. Eur J Med Chem. 2015 Mar 6;92:754-65. doi: 10.1016/j.ejmech.2015.01.042. Epub 2015 Jan 22. Eur J Med Chem. 2015. PMID: 25626145

6

Fused heterocycles bearing bridgehead nitrogen as potent HIV-1 NNRTIs. Part 4: design, synthesis and biological evaluation of novel imidazo[1,2-a]pyrazines.

Huang B, Liang X, Li C, Chen W, Liu T, Li X, Sun Y, Fu L, Liu H, De Clercq E, Pannecouque C, Zhan P, Liu X. Huang B, et al. Eur J Med Chem. 2015 Mar 26;93:330-7. doi: 10.1016/j.ejmech.2015.02.022. Epub 2015 Feb 16. Eur J Med Chem. 2015. PMID: 25707013

7

Discovery of bioactive molecules from CuAAC click-chemistry-based combinatorial libraries.

Wang X, Huang B, Liu X, Zhan P. Wang X, et al. Among authors: huang b. Drug Discov Today. 2016 Jan;21(1):118-132. doi: 10.1016/j.drudis.2015.08.004. Epub 2015 Aug 24. Drug Discov Today. 2016. PMID: 26315392 Review.

8

Design, Synthesis, and Biological Evaluation of Novel 2-(Pyridin-3-yloxy)acetamide Derivatives as Potential Anti-HIV-1 Agents.

Huang B, Li X, Zhan P, De Clercq E, Daelemans D, Pannecouque C, Liu X. Huang B, et al. Chem Biol Drug Des. 2016 Feb;87(2):283-9. doi: 10.1111/cbdd.12657. Epub 2015 Sep 29. Chem Biol Drug Des. 2016. PMID: 26347922

9

Fragment-based approaches to anti-HIV drug discovery: state of the art and future opportunities.

Huang B, Kang D, Zhan P, Liu X. Huang B, et al. Expert Opin Drug Discov. 2015 Dec;10(12):1271-81. doi: 10.1517/17460441.2015.1083007. Epub 2015 Sep 15. Expert Opin Drug Discov. 2015. PMID: 26372893 Review.

10

Novel fluorine-containing DAPY derivatives as potent HIV-1 NNRTIs: a patent evaluation of WO2014072419.

Meng Q, Liu N, Huang B, Zhan P, Liu X. Meng Q, et al. Among authors: huang b. Expert Opin Ther Pat. 2015;25(12):1477-86. doi: 10.1517/13543776.2016.1088832. Epub 2015 Sep 28. Expert Opin Ther Pat. 2015. PMID: 26415039

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