Lin T - Search Results

1

Effect of Hepatic Impairment on the Pharmacokinetics of Pradigastat, a Diacylglycerol Acyltransferase 1 (DGAT1) Inhibitor.

Hirano M, Meyers D, Golla G, Pal P, Pinot P, Lin T, Majumdar T, Rebello S, Sunkara G, Chen J. Hirano M, et al. Among authors: lin t. Clin Pharmacokinet. 2015 Jul;54(7):761-70. doi: 10.1007/s40262-015-0235-9. Clin Pharmacokinet. 2015. PMID: 25633714 Clinical Trial.

2

Effect of Renal Impairment on the Pharmacokinetics of Pradigastat, a Novel Diacylglycerol Acyltransferase1 (DGAT1) Inhibitor.

Mita S, Meyers D, Pal P, Lin T, Majumdar T, Rebello S, Sunkara G, Chen J. Mita S, et al. Among authors: lin t. Clin Pharmacokinet. 2015 Jul;54(7):751-60. doi: 10.1007/s40262-015-0234-x. Clin Pharmacokinet. 2015. PMID: 25627776 Clinical Trial.

3

Pharmacokinetics and safety of sacubitril/valsartan (LCZ696) in patients with mild and moderate hepatic impairment .

Kulmatycki KM, Langenickel T, Ng WH, Pal P, Zhou W, Lin TH, Rajman I, Chandra P, Sunkara G. Kulmatycki KM, et al. Among authors: lin th. Int J Clin Pharmacol Ther. 2017 Sep;55(9):728-739. doi: 10.5414/CP202988. Int J Clin Pharmacol Ther. 2017. PMID: 28737127

4

Effects of hepatic impairment on the pharmacokinetics of nilotinib: an open-label, single-dose, parallel-group study.

Yin OQ, Gallagher N, Tanaka C, Fisher D, Sethuraman V, Zhou W, Lin TH, Heuman D, Schran H. Yin OQ, et al. Clin Ther. 2009;31 Pt 2:2459-69. doi: 10.1016/j.clinthera.2009.11.015. Clin Ther. 2009. PMID: 20110053 Clinical Trial.

5

Pharmacokinetics and pharmacodynamics of LCZ696, a novel dual-acting angiotensin receptor-neprilysin inhibitor (ARNi).

Gu J, Noe A, Chandra P, Al-Fayoumi S, Ligueros-Saylan M, Sarangapani R, Maahs S, Ksander G, Rigel DF, Jeng AY, Lin TH, Zheng W, Dole WP. Gu J, et al. J Clin Pharmacol. 2010 Apr;50(4):401-14. doi: 10.1177/0091270009343932. Epub 2009 Nov 23. J Clin Pharmacol. 2010. PMID: 19934029 Clinical Trial.

6

Nilotinib preclinical pharmacokinetics and practical application toward clinical projections of oral absorption and systemic availability.

Xia B, Heimbach T, He H, Lin TH. Xia B, et al. Among authors: lin th. Biopharm Drug Dispos. 2012 Dec;33(9):536-49. doi: 10.1002/bdd.1821. Epub 2012 Nov 19. Biopharm Drug Dispos. 2012. PMID: 23097199

7

Evaluation of Drug-Drug Interaction Potential Between Sacubitril/Valsartan (LCZ696) and Statins Using a Physiologically Based Pharmacokinetic Model.

Lin W, Ji T, Einolf H, Ayalasomayajula S, Lin TH, Hanna I, Heimbach T, Breen C, Jarugula V, He H. Lin W, et al. Among authors: lin th. J Pharm Sci. 2017 May;106(5):1439-1451. doi: 10.1016/j.xphs.2017.01.007. Epub 2017 Jan 13. J Pharm Sci. 2017. PMID: 28089685

8

Novel physiologically based pharmacokinetic modeling of patupilone for human pharmacokinetic predictions.

Xia B, Heimbach T, Lin TH, He H, Wang Y, Tan E. Xia B, et al. Among authors: lin th. Cancer Chemother Pharmacol. 2012 Jun;69(6):1567-82. doi: 10.1007/s00280-012-1863-5. Epub 2012 Apr 11. Cancer Chemother Pharmacol. 2012. PMID: 22526410

9

Osilodrostat (LCI699), a potent 11β-hydroxylase inhibitor, administered in combination with the multireceptor-targeted somatostatin analog pasireotide: A 13-week study in rats.

Li L, Vashisht K, Boisclair J, Li W, Lin TH, Schmid HA, Kluwe W, Schoenfeld H, Hoffmann P. Li L, et al. Toxicol Appl Pharmacol. 2015 Aug 1;286(3):224-33. doi: 10.1016/j.taap.2015.05.004. Epub 2015 May 14. Toxicol Appl Pharmacol. 2015. PMID: 25981165 Free article.

10

Application of physiologically based absorption modeling to formulation development of a low solubility, low permeability weak base: mechanistic investigation of food effect.

Zhang H, Xia B, Sheng J, Heimbach T, Lin TH, He H, Wang Y, Novick S, Comfort A. Zhang H, et al. Among authors: lin th. AAPS PharmSciTech. 2014 Apr;15(2):400-6. doi: 10.1208/s12249-014-0075-1. Epub 2014 Jan 17. AAPS PharmSciTech. 2014. PMID: 24435225 Free PMC article.

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