Upton A - Search Results

1

The tuberculosis drug discovery and development pipeline and emerging drug targets.

Mdluli K, Kaneko T, Upton A. Mdluli K, et al. Among authors: upton a. Cold Spring Harb Perspect Med. 2015 Jan 29;5(6):a021154. doi: 10.1101/cshperspect.a021154. Cold Spring Harb Perspect Med. 2015. PMID: 25635061 Free PMC article. Review.

2

In vitro and in vivo activity of clofazimine against Mycobacterium tuberculosis persisters.

Xu J, Lu Y, Fu L, Zhu H, Wang B, Mdluli K, Upton AM, Jin H, Zheng M, Zhao W, Li P. Xu J, et al. Among authors: upton am. Int J Tuberc Lung Dis. 2012 Aug;16(8):1119-25. doi: 10.5588/ijtld.11.0752. Epub 2012 Jun 12. Int J Tuberc Lung Dis. 2012. PMID: 22691726

3

Design, synthesis, and structure-activity relationship studies of tryptanthrins as antitubercular agents.

Hwang JM, Oh T, Kaneko T, Upton AM, Franzblau SG, Ma Z, Cho SN, Kim P. Hwang JM, et al. J Nat Prod. 2013 Mar 22;76(3):354-67. doi: 10.1021/np3007167. Epub 2013 Jan 29. J Nat Prod. 2013. PMID: 23360475

4

Tuberculosis drug discovery and emerging targets.

Mdluli K, Kaneko T, Upton A. Mdluli K, et al. Among authors: upton a. Ann N Y Acad Sci. 2014 Sep;1323:56-75. doi: 10.1111/nyas.12459. Epub 2014 Jun 11. Ann N Y Acad Sci. 2014. PMID: 24920100 Review.

5

In vitro and in vivo activities of the nitroimidazole TBA-354 against Mycobacterium tuberculosis.

Upton AM, Cho S, Yang TJ, Kim Y, Wang Y, Lu Y, Wang B, Xu J, Mdluli K, Ma Z, Franzblau SG. Upton AM, et al. Antimicrob Agents Chemother. 2015 Jan;59(1):136-44. doi: 10.1128/AAC.03823-14. Epub 2014 Oct 20. Antimicrob Agents Chemother. 2015. PMID: 25331696 Free PMC article.

6

Contribution of the nitroimidazoles PA-824 and TBA-354 to the activity of novel regimens in murine models of tuberculosis.

Tasneen R, Williams K, Amoabeng O, Minkowski A, Mdluli KE, Upton AM, Nuermberger EL. Tasneen R, et al. Among authors: upton am. Antimicrob Agents Chemother. 2015 Jan;59(1):129-35. doi: 10.1128/AAC.03822-14. Epub 2014 Oct 20. Antimicrob Agents Chemother. 2015. PMID: 25331697 Free PMC article.

7

Identification and optimization of a new series of anti-tubercular quinazolinones.

Couturier C, Lair C, Pellet A, Upton A, Kaneko T, Perron C, Cogo E, Menegotto J, Bauer A, Scheiper B, Lagrange S, Bacqué E. Couturier C, et al. Among authors: upton a. Bioorg Med Chem Lett. 2016 Nov 1;26(21):5290-5299. doi: 10.1016/j.bmcl.2016.09.043. Epub 2016 Sep 16. Bioorg Med Chem Lett. 2016. PMID: 27671498

8

Contribution of Pretomanid to Novel Regimens Containing Bedaquiline with either Linezolid or Moxifloxacin and Pyrazinamide in Murine Models of Tuberculosis.

Xu J, Li SY, Almeida DV, Tasneen R, Barnes-Boyle K, Converse PJ, Upton AM, Mdluli K, Fotouhi N, Nuermberger EL. Xu J, et al. Antimicrob Agents Chemother. 2019 Apr 25;63(5):e00021-19. doi: 10.1128/AAC.00021-19. Print 2019 May. Antimicrob Agents Chemother. 2019. PMID: 30833432 Free PMC article.

9

Comparative Efficacy of the Novel Diarylquinoline TBAJ-587 and Bedaquiline against a Resistant Rv0678 Mutant in a Mouse Model of Tuberculosis.

Xu J, Converse PJ, Upton AM, Mdluli K, Fotouhi N, Nuermberger EL. Xu J, et al. Antimicrob Agents Chemother. 2021 Mar 18;65(4):e02418-20. doi: 10.1128/AAC.02418-20. Print 2021 Mar 18. Antimicrob Agents Chemother. 2021. PMID: 33526488 Free PMC article.

10

Predictive Modeling to Study the Treatment-Shortening Potential of Novel Tuberculosis Drug Regimens, Toward Bundling of Preclinical Data.

Mudde SE, Ayoun Alsoud R, van der Meijden A, Upton AM, Lotlikar MU, Simonsson USH, Bax HI, de Steenwinkel JEM. Mudde SE, et al. Among authors: upton am. J Infect Dis. 2022 Jun 1;225(11):1876-1885. doi: 10.1093/infdis/jiab101. J Infect Dis. 2022. PMID: 33606880 Free PMC article.

Save citations to file

Email citations

Send citations to clipboard

Add to Collections

Add to My Bibliography

Create a file for external citation management software

Your saved search

Your RSS Feed

My Custom Filters

Publication date

Text availability

Article attribute

Article type

Article Language

Species

Sex

Age

Other

474 results

Search Page

Filters