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Interleukin-12 (IL-12) enhancement of the cellular immune response against human immunodeficiency virus type 1 env antigen in a DNA prime/vaccinia virus boost vaccine regimen is time and dose dependent: suppressive effects of IL-12 boost are mediated by nitric oxide.
Gherardi MM, Ramírez JC, Esteban M. Gherardi MM, et al. Among authors: esteban m. J Virol. 2000 Jul;74(14):6278-86. doi: 10.1128/jvi.74.14.6278-6286.2000. J Virol. 2000. PMID: 10864637 Free PMC article.
The combination of DNA vectors expressing IL-12 + IL-18 elicits high protective immune response against cutaneous leishmaniasis after priming with DNA-p36/LACK and the cytokines, followed by a booster with a vaccinia virus recombinant expressing p36/LACK.
Tapia E, Pérez-Jiménez E, López-Fuertes L, Gonzalo R, Gherardi MM, Esteban M. Tapia E, et al. Among authors: esteban m. Microbes Infect. 2003 Feb;5(2):73-84. doi: 10.1016/s1286-4579(02)00077-1. Microbes Infect. 2003. PMID: 12650765 Free article.
Prime-boost immunization schedules based on influenza virus and vaccinia virus vectors potentiate cellular immune responses against human immunodeficiency virus Env protein systemically and in the genitorectal draining lymph nodes.
Gherardi MM, Nájera JL, Pérez-Jiménez E, Guerra S, García-Sastre A, Esteban M. Gherardi MM, et al. Among authors: esteban m. J Virol. 2003 Jun;77(12):7048-57. doi: 10.1128/jvi.77.12.7048-7057.2003. J Virol. 2003. PMID: 12768024 Free PMC article.
1,238 results