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Knockout of mitochondrial thioredoxin reductase stabilizes prolyl hydroxylase 2 and inhibits tumor growth and tumor-derived angiogenesis.
Hellfritsch J, Kirsch J, Schneider M, Fluege T, Wortmann M, Frijhoff J, Dagnell M, Fey T, Esposito I, Kölle P, Pogoda K, Angeli JP, Ingold I, Kuhlencordt P, Östman A, Pohl U, Conrad M, Beck H. Hellfritsch J, et al. Among authors: pohl u. Antioxid Redox Signal. 2015 Apr 10;22(11):938-50. doi: 10.1089/ars.2014.5889. Antioxid Redox Signal. 2015. PMID: 25647640 Free PMC article.
Endothelial Dysfunction, and A Prothrombotic, Proinflammatory Phenotype Is Caused by Loss of Mitochondrial Thioredoxin Reductase in Endothelium.
Kirsch J, Schneider H, Pagel JI, Rehberg M, Singer M, Hellfritsch J, Chillo O, Schubert KM, Qiu J, Pogoda K, Kameritsch P, Uhl B, Pircher J, Deindl E, Müller S, Kirchner T, Pohl U, Conrad M, Beck H. Kirsch J, et al. Among authors: pohl u. Arterioscler Thromb Vasc Biol. 2016 Sep;36(9):1891-9. doi: 10.1161/ATVBAHA.116.307843. Epub 2016 Jul 7. Arterioscler Thromb Vasc Biol. 2016. PMID: 27386940
The mitochondrial thioredoxin reductase system (TrxR2) in vascular endothelium controls peroxynitrite levels and tissue integrity.
Kameritsch P, Singer M, Nuernbergk C, Rios N, Reyes AM, Schmidt K, Kirsch J, Schneider H, Müller S, Pogoda K, Cui R, Kirchner T, de Wit C, Lange-Sperandio B, Pohl U, Conrad M, Radi R, Beck H. Kameritsch P, et al. Among authors: pohl u. Proc Natl Acad Sci U S A. 2021 Feb 16;118(7):e1921828118. doi: 10.1073/pnas.1921828118. Proc Natl Acad Sci U S A. 2021. PMID: 33579817 Free PMC article.
PKA negatively modulates the migration enhancing effect of Connexin 43.
Kameritsch P, Kiemer F, Mannell H, Beck H, Pohl U, Pogoda K. Kameritsch P, et al. Among authors: pohl u. Biochim Biophys Acta Mol Cell Res. 2019 May;1866(5):828-838. doi: 10.1016/j.bbamcr.2019.02.001. Epub 2019 Feb 12. Biochim Biophys Acta Mol Cell Res. 2019. PMID: 30769008 Free article.
263 results