Ming X - Search Results

1

High-throughput screening identifies small molecules that enhance the pharmacological effects of oligonucleotides.

Yang B, Ming X, Cao C, Laing B, Yuan A, Porter MA, Hull-Ryde EA, Maddry J, Suto M, Janzen WP, Juliano RL. Yang B, et al. Among authors: ming x. Nucleic Acids Res. 2015 Feb 27;43(4):1987-96. doi: 10.1093/nar/gkv060. Epub 2015 Feb 6. Nucleic Acids Res. 2015. PMID: 25662226 Free PMC article.

2

Receptors, endocytosis, and trafficking: the biological basis of targeted delivery of antisense and siRNA oligonucleotides.

Juliano RL, Carver K, Cao C, Ming X. Juliano RL, et al. Among authors: ming x. J Drug Target. 2013 Jan;21(1):27-43. doi: 10.3109/1061186X.2012.740674. Epub 2012 Nov 19. J Drug Target. 2013. PMID: 23163768 Free PMC article. Review.

3

A Novel Family of Small Molecules that Enhance the Intracellular Delivery and Pharmacological Effectiveness of Antisense and Splice Switching Oligonucleotides.

Wang L, Ariyarathna Y, Ming X, Yang B, James LI, Kreda SM, Porter M, Janzen W, Juliano RL. Wang L, et al. Among authors: ming x. ACS Chem Biol. 2017 Aug 18;12(8):1999-2007. doi: 10.1021/acschembio.7b00242. Epub 2017 Jul 14. ACS Chem Biol. 2017. PMID: 28703575 Free PMC article.

4

Structure-activity relationships and cellular mechanism of action of small molecules that enhance the delivery of oligonucleotides.

Juliano RL, Wang L, Tavares F, Brown EG, James L, Ariyarathna Y, Ming X, Mao C, Suto M. Juliano RL, et al. Among authors: ming x. Nucleic Acids Res. 2018 Feb 28;46(4):1601-1613. doi: 10.1093/nar/gkx1320. Nucleic Acids Res. 2018. PMID: 29361039 Free PMC article.

5

Intracellular delivery of an antisense oligonucleotide via endocytosis of a G protein-coupled receptor.

Ming X, Alam MR, Fisher M, Yan Y, Chen X, Juliano RL. Ming X, et al. Nucleic Acids Res. 2010 Oct;38(19):6567-76. doi: 10.1093/nar/gkq534. Epub 2010 Jun 15. Nucleic Acids Res. 2010. PMID: 20551131 Free PMC article.

6

Cellular uptake and intracellular trafficking of antisense and siRNA oligonucleotides.

Juliano RL, Ming X, Nakagawa O. Juliano RL, et al. Among authors: ming x. Bioconjug Chem. 2012 Feb 15;23(2):147-57. doi: 10.1021/bc200377d. Epub 2011 Oct 27. Bioconjug Chem. 2012. PMID: 21992697 Free PMC article. Review.

7

The small molecule Retro-1 enhances the pharmacological actions of antisense and splice switching oligonucleotides.

Ming X, Carver K, Fisher M, Noel R, Cintrat JC, Gillet D, Barbier J, Cao C, Bauman J, Juliano RL. Ming X, et al. Nucleic Acids Res. 2013 Apr 1;41(6):3673-87. doi: 10.1093/nar/gkt066. Epub 2013 Feb 8. Nucleic Acids Res. 2013. PMID: 23396438 Free PMC article.

8

Covalent conjugation of oligonucleotides with cell-targeting ligands.

Alam MR, Ming X, Nakagawa O, Jin J, Juliano RL. Alam MR, et al. Among authors: ming x. Bioorg Med Chem. 2013 Oct 15;21(20):6217-23. doi: 10.1016/j.bmc.2013.05.037. Epub 2013 Jun 1. Bioorg Med Chem. 2013. PMID: 23777829 Free PMC article.

9

Cellular uptake and intracellular trafficking of oligonucleotides: implications for oligonucleotide pharmacology.

Juliano RL, Ming X, Carver K, Laing B. Juliano RL, et al. Among authors: ming x. Nucleic Acid Ther. 2014 Apr;24(2):101-13. doi: 10.1089/nat.2013.0463. Epub 2014 Jan 2. Nucleic Acid Ther. 2014. PMID: 24383421 Free PMC article. Review.

10

Biological barriers to therapy with antisense and siRNA oligonucleotides.

Juliano R, Bauman J, Kang H, Ming X. Juliano R, et al. Among authors: ming x. Mol Pharm. 2009 May-Jun;6(3):686-95. doi: 10.1021/mp900093r. Mol Pharm. 2009. PMID: 19397332 Free PMC article. Review.

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