Vesci L - Search Results

1

Preclinical antitumor activity of ST7612AA1: a new oral thiol-based histone deacetylase (HDAC) inhibitor.

Vesci L, Bernasconi E, Milazzo FM, De Santis R, Gaudio E, Kwee I, Rinaldi A, Pace S, Carollo V, Giannini G, Bertoni F. Vesci L, et al. Oncotarget. 2015 Mar 20;6(8):5735-48. doi: 10.18632/oncotarget.3240. Oncotarget. 2015. PMID: 25671299 Free PMC article.

2

Preclinical antitumor activity of SST0116CL1: a novel heat shock protein 90 inhibitor.

Vesci L, Milazzo FM, Carollo V, Pace S, Giannini G. Vesci L, et al. Int J Oncol. 2014 Oct;45(4):1421-9. doi: 10.3892/ijo.2014.2575. Epub 2014 Aug 1. Int J Oncol. 2014. PMID: 25096516 Free PMC article.

3

ST7612AA1, a thioacetate-ω(γ-lactam carboxamide) derivative selected from a novel generation of oral HDAC inhibitors.

Giannini G, Vesci L, Battistuzzi G, Vignola D, Milazzo FM, Guglielmi MB, Barbarino M, Santaniello M, Fantò N, Mor M, Rivara S, Pala D, Taddei M, Pisano C, Cabri W. Giannini G, et al. Among authors: vesci l. J Med Chem. 2014 Oct 23;57(20):8358-77. doi: 10.1021/jm5008209. Epub 2014 Oct 8. J Med Chem. 2014. PMID: 25233084

4

Intra-tumor AvidinOX allows efficacy of low dose systemic biotinylated Cetuximab in a model of head and neck cancer.

Vesci L, Milazzo FM, Anastasi AM, Petronzelli F, Chiapparino C, Carollo V, Roscilli G, Marra E, Luberto L, Aurisicchio L, Pacello ML, Spagnoli LG, De Santis R. Vesci L, et al. Oncotarget. 2016 Jan 5;7(1):914-28. doi: 10.18632/oncotarget.6089. Oncotarget. 2016. PMID: 26575422 Free PMC article.

5

N-Hydroxy-(4-oxime)-cinnamide: a versatile scaffold for the synthesis of novel histone deacetylase [correction of deacetilase] (HDAC) inhibitors.

Giannini G, Marzi M, Pezzi R, Brunetti T, Battistuzzi G, Marzo MD, Cabri W, Vesci L, Pisano C. Giannini G, et al. Among authors: vesci l. Bioorg Med Chem Lett. 2009 Apr 15;19(8):2346-9. doi: 10.1016/j.bmcl.2009.02.029. Epub 2009 Feb 12. Bioorg Med Chem Lett. 2009. PMID: 19285395

6

Exploring bis-(indolyl)methane moiety as an alternative and innovative CAP group in the design of histone deacetylase (HDAC) inhibitors.

Giannini G, Marzi M, Marzo MD, Battistuzzi G, Pezzi R, Brunetti T, Cabri W, Vesci L, Pisano C. Giannini G, et al. Among authors: vesci l. Bioorg Med Chem Lett. 2009 May 15;19(10):2840-3. doi: 10.1016/j.bmcl.2009.03.101. Epub 2009 Mar 26. Bioorg Med Chem Lett. 2009. PMID: 19359173

7

Metabolic approach to the enhancement of antitumor effect of chemotherapy: a key role of acetyl-L-carnitine.

Pisano C, Vesci L, Milazzo FM, Guglielmi MB, Foderà R, Barbarino M, D'Incalci M, Zucchetti M, Petrangolini G, Tortoreto M, Perego P, Zuco V, Orlandi A, Passeri D, Carminati P, Cavazza C, Zunino F. Pisano C, et al. Among authors: vesci l. Clin Cancer Res. 2010 Aug 1;16(15):3944-53. doi: 10.1158/1078-0432.CCR-10-0964. Epub 2010 Jun 18. Clin Cancer Res. 2010. PMID: 20562210

8

Novel PARP-1 inhibitors based on a 2-propanoyl-3H-quinazolin-4-one scaffold.

Giannini G, Battistuzzi G, Vesci L, Milazzo FM, De Paolis F, Barbarino M, Guglielmi MB, Carollo V, Gallo G, Artali R, Dallavalle S. Giannini G, et al. Among authors: vesci l. Bioorg Med Chem Lett. 2014 Jan 15;24(2):462-6. doi: 10.1016/j.bmcl.2013.12.048. Epub 2013 Dec 18. Bioorg Med Chem Lett. 2014. PMID: 24388690 Free article.

9

Trastuzumab and docetaxel in a preclinical organotypic breast cancer model using tissue slices from mammary fat pad: Translational relevance.

Vesci L, Carollo V, Roscilli G, Aurisicchio L, Ferrara FF, Spagnoli L, De Santis R. Vesci L, et al. Oncol Rep. 2015 Sep;34(3):1146-52. doi: 10.3892/or.2015.4074. Epub 2015 Jun 24. Oncol Rep. 2015. PMID: 26133490 Free PMC article.

10

The novel atypical retinoid ST5589 down-regulates Aurora Kinase A and has anti-tumour activity in lymphoma pre-clinical models.

Bernasconi E, Gaudio E, Kwee I, Rinaldi A, Cascione L, Tarantelli C, Mensah AA, Stathis A, Zucca E, Vesci L, Giannini G, Bertoni F. Bernasconi E, et al. Among authors: vesci l. Br J Haematol. 2015 Nov;171(3):378-86. doi: 10.1111/bjh.13595. Epub 2015 Aug 3. Br J Haematol. 2015. PMID: 26235926 Free article.

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