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Mitochondrial and cytoplasmic ROS have opposing effects on lifespan.
Schaar CE, Dues DJ, Spielbauer KK, Machiela E, Cooper JF, Senchuk M, Hekimi S, Van Raamsdonk JM. Schaar CE, et al. PLoS Genet. 2015 Feb 11;11(2):e1004972. doi: 10.1371/journal.pgen.1004972. eCollection 2015 Feb. PLoS Genet. 2015. PMID: 25671321 Free PMC article.