Hausheer FH - Search Results

1

Novel covalent modification of human anaplastic lymphoma kinase (ALK) and potentiation of crizotinib-mediated inhibition of ALK activity by BNP7787.

Parker AR, Petluru PN, Nienaber VL, Zhao M, Ayala PY, Badger J, Chie-Leon B, Sridhar V, Logan C, Kochat H, Hausheer FH. Parker AR, et al. Among authors: hausheer fh. Onco Targets Ther. 2015 Feb 4;8:375-83. doi: 10.2147/OTT.S73690. eCollection 2015. Onco Targets Ther. 2015. PMID: 25678804 Free PMC article.

2

Mechanistic study of BNP7787-mediated cisplatin nephroprotection: modulation of gamma-glutamyl transpeptidase.

Hausheer FH, Shanmugarajah D, Leverett BD, Chen X, Huang Q, Kochat H, Petluru PN, Parker AR. Hausheer FH, et al. Cancer Chemother Pharmacol. 2010 Apr;65(5):941-51. doi: 10.1007/s00280-009-1101-y. Epub 2009 Aug 28. Cancer Chemother Pharmacol. 2010. PMID: 19714332

3

BNP7787-mediated modulation of paclitaxel- and cisplatin-induced aberrant microtubule protein polymerization in vitro.

Parker AR, Petluru PN, Wu M, Zhao M, Kochat H, Hausheer FH. Parker AR, et al. Among authors: hausheer fh. Mol Cancer Ther. 2010 Sep;9(9):2558-67. doi: 10.1158/1535-7163.MCT-10-0300. Epub 2010 Aug 31. Mol Cancer Ther. 2010. PMID: 20807779

4

Cysteine specific targeting of the functionally distinct peroxiredoxin and glutaredoxin proteins by the investigational disulfide BNP7787.

Parker AR, Petluru PN, Nienaber VL, Badger J, Leverett BD, Jair K, Sridhar V, Logan C, Ayala PY, Kochat H, Hausheer FH. Parker AR, et al. Among authors: hausheer fh. Molecules. 2015 Mar 18;20(3):4928-50. doi: 10.3390/molecules20034928. Molecules. 2015. PMID: 25793542 Free PMC article.

5

Analysis of BNP7787 thiol-disulfide exchange reactions in phosphate buffer and human plasma using microscale electrochemical high performance liquid chromatography.

Shanmugarajah D, Ding D, Huang Q, Chen X, Kochat H, Petluru PN, Ayala PY, Parker AR, Hausheer FH. Shanmugarajah D, et al. Among authors: hausheer fh. J Chromatogr B Analyt Technol Biomed Life Sci. 2009 Apr 1;877(10):857-66. doi: 10.1016/j.jchromb.2009.02.056. Epub 2009 Feb 28. J Chromatogr B Analyt Technol Biomed Life Sci. 2009. PMID: 19278906

6

Mechanistic study of BNP7787-mediated cisplatin nephroprotection: modulation of human aminopeptidase N.

Hausheer FH, Parker AR, Petluru PN, Jair KW, Chen S, Huang Q, Chen X, Ayala PY, Shanmugarajah D, Kochat H. Hausheer FH, et al. Cancer Chemother Pharmacol. 2011 Feb;67(2):381-91. doi: 10.1007/s00280-010-1333-x. Epub 2010 May 4. Cancer Chemother Pharmacol. 2011. PMID: 20440617

7

Accumulation of BNP7787 in human renal proximal tubule cells.

Hausheer FH, Ding D, Shanmugarajah D, Leverett BD, Huang Q, Chen X, Kochat H, Ayala PY, Petluru PN, Parker AR. Hausheer FH, et al. J Pharm Sci. 2011 Sep;100(9):3977-84. doi: 10.1002/jps.22510. Epub 2011 Feb 22. J Pharm Sci. 2011. PMID: 21344411

8

Stabilization of the Karenitecin® lactone by alpha-1 acid glycoprotein.

Yao S, Petluru P, Parker A, Ding D, Chen X, Huang Q, Kochat H, Hausheer F. Yao S, et al. Cancer Chemother Pharmacol. 2015 Apr;75(4):719-28. doi: 10.1007/s00280-015-2686-y. Epub 2015 Jan 30. Cancer Chemother Pharmacol. 2015. PMID: 25634596

9

New approaches to drug discovery and development: a mechanism-based approach to pharmaceutical research and its application to BNP7787, a novel chemoprotective agent.

Hausheer FH, Kochat H, Parker AR, Ding D, Yao S, Hamilton SE, Petluru PN, Leverett BD, Bain SH, Saxe JD. Hausheer FH, et al. Cancer Chemother Pharmacol. 2003 Jul;52 Suppl 1:S3-15. doi: 10.1007/s00280-003-0653-5. Epub 2003 Jun 18. Cancer Chemother Pharmacol. 2003. PMID: 12819940 Review.

10

Topotecan lactone selectively binds to double- and single-stranded DNA in the absence of topoisomerase I.

Yao S, Murali D, Seetharamulu P, Haridas K, Petluru PN, Reddy DG, Hausheer FH. Yao S, et al. Among authors: hausheer fh. Cancer Res. 1998 Sep 1;58(17):3782-6. Cancer Res. 1998. PMID: 9731484

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