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Endogenous levels of 1-O-acylceramides increase upon acidic ceramidase deficiency and decrease due to loss of Dgat1 in a tissue-dependent manner.
Bayerle A, Marsching C, Rabionet M, Dworski S, Kamani MA, Chitraju C, Gluchowski NL, Gabriel KR, Herzer S, Jennemann R, Levade T, Medin JA, Sandhoff R. Bayerle A, et al. Among authors: herzer s. Biochim Biophys Acta Mol Cell Biol Lipids. 2020 Sep;1865(9):158741. doi: 10.1016/j.bbalip.2020.158741. Epub 2020 May 28. Biochim Biophys Acta Mol Cell Biol Lipids. 2020. PMID: 32474112
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