O'Bryan JP - Search Results

1

UCR1C is a novel activator of phosphodiesterase 4 (PDE4) long isoforms and attenuates cardiomyocyte hypertrophy.

Wang L, Burmeister BT, Johnson KR, Baillie GS, Karginov AV, Skidgel RA, O'Bryan JP, Carnegie GK. Wang L, et al. Cell Signal. 2015 May;27(5):908-22. doi: 10.1016/j.cellsig.2015.02.003. Epub 2015 Feb 12. Cell Signal. 2015. PMID: 25683917 Free PMC article.

2

Intersectin (ITSN) family of scaffolds function as molecular hubs in protein interaction networks.

Wong KA, Wilson J, Russo A, Wang L, Okur MN, Wang X, Martin NP, Scappini E, Carnegie GK, O'Bryan JP. Wong KA, et al. PLoS One. 2012;7(4):e36023. doi: 10.1371/journal.pone.0036023. Epub 2012 Apr 27. PLoS One. 2012. PMID: 22558309 Free PMC article.

3

Receptor tyrosine kinase ubiquitylation involves the dynamic regulation of Cbl-Spry2 by intersectin 1 and the Shp2 tyrosine phosphatase.

Okur MN, Russo A, O'Bryan JP. Okur MN, et al. Mol Cell Biol. 2014 Jan;34(2):271-9. doi: 10.1128/MCB.00850-13. Epub 2013 Nov 11. Mol Cell Biol. 2014. PMID: 24216759 Free PMC article.

4

Protein Kinase A (PKA) Phosphorylation of Shp2 Protein Inhibits Its Phosphatase Activity and Modulates Ligand Specificity.

Burmeister BT, Wang L, Gold MG, Skidgel RA, O'Bryan JP, Carnegie GK. Burmeister BT, et al. J Biol Chem. 2015 May 8;290(19):12058-67. doi: 10.1074/jbc.M115.642983. Epub 2015 Mar 23. J Biol Chem. 2015. PMID: 25802336 Free PMC article.

5

Intersectin 1 enhances Cbl ubiquitylation of epidermal growth factor receptor through regulation of Sprouty2-Cbl interaction.

Okur MN, Ooi J, Fong CW, Martinez N, Garcia-Dominguez C, Rojas JM, Guy G, O'Bryan JP. Okur MN, et al. Mol Cell Biol. 2012 Feb;32(4):817-25. doi: 10.1128/MCB.05647-11. Epub 2011 Dec 12. Mol Cell Biol. 2012. PMID: 22158968 Free PMC article.

6

Targeting the α4-α5 interface of RAS results in multiple levels of inhibition.

Spencer-Smith R, Li L, Prasad S, Koide A, Koide S, O'Bryan JP. Spencer-Smith R, et al. Small GTPases. 2019 Sep;10(5):378-387. doi: 10.1080/21541248.2017.1333188. Epub 2017 Dec 31. Small GTPases. 2019. PMID: 28692342 Free PMC article.

7

Cooperative role of caveolin-1 and C-terminal Src kinase binding protein in C-terminal Src kinase-mediated negative regulation of c-Src.

Place AT, Chen Z, Bakhshi FR, Liu G, O'Bryan JP, Minshall RD. Place AT, et al. Mol Pharmacol. 2011 Oct;80(4):665-72. doi: 10.1124/mol.111.073957. Epub 2011 Jul 21. Mol Pharmacol. 2011. PMID: 21778303 Free PMC article.

8

A new dimension to Ras function: a novel role for nucleotide-free Ras in Class II phosphatidylinositol 3-kinase beta (PI3KC2β) regulation.

Wong KA, Russo A, Wang X, Chen YJ, Lavie A, O'Bryan JP. Wong KA, et al. PLoS One. 2012;7(9):e45360. doi: 10.1371/journal.pone.0045360. Epub 2012 Sep 13. PLoS One. 2012. PMID: 23028960 Free PMC article.

9

Emerging roles for intersectin (ITSN) in regulating signaling and disease pathways.

Hunter MP, Russo A, O'Bryan JP. Hunter MP, et al. Int J Mol Sci. 2013 Apr 10;14(4):7829-52. doi: 10.3390/ijms14047829. Int J Mol Sci. 2013. PMID: 23574942 Free PMC article. Review.

10

Phosphatidylinositol 3-kinase, class 2 beta (PI3KC2β) isoform contributes to neuroblastoma tumorigenesis.

Russo A, Okur MN, Bosland M, O'Bryan JP. Russo A, et al. Cancer Lett. 2015 Apr 10;359(2):262-8. doi: 10.1016/j.canlet.2015.01.026. Epub 2015 Jan 23. Cancer Lett. 2015. PMID: 25622909 Free PMC article.

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