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Page 1
Machine Learning for Myocardial Infarction Compared With Guideline-Recommended Diagnostic Pathways.
Boeddinghaus J, Doudesis D, Lopez-Ayala P, Lee KK, Koechlin L, Wildi K, Nestelberger T, Borer R, Miró Ò, Martin-Sanchez FJ, Strebel I, Rubini Giménez M, Keller DI, Christ M, Bularga A, Li Z, Ferry AV, Tuck C, Anand A, Gray A, Mills NL, Mueller C; CoDE-ACS and APACE Investigators. Boeddinghaus J, et al. Circulation. 2024 Apr 2;149(14):1090-1101. doi: 10.1161/CIRCULATIONAHA.123.066917. Epub 2024 Feb 12. Circulation. 2024. PMID: 38344871
Improved cytosine base editors generated from TadA variants.
Lam DK, Feliciano PR, Arif A, Bohnuud T, Fernandez TP, Gehrke JM, Grayson P, Lee KD, Ortega MA, Sawyer C, Schwaegerle ND, Peraro L, Young L, Lee SJ, Ciaramella G, Gaudelli NM. Lam DK, et al. Among authors: gehrke jm. Nat Biotechnol. 2023 May;41(5):686-697. doi: 10.1038/s41587-022-01611-9. Epub 2023 Jan 9. Nat Biotechnol. 2023. PMID: 36624149 Free PMC article.
Extending the no objective testing rules to patients triaged by the European Society of Cardiology 0/1-hour algorithms.
Ratmann PD, Boeddinghaus J, Nestelberger T, Lopez-Ayala P, Huré G, Gehrke J, Koechlin L, Wildi K, Mueller P, Bima P, Wussler D, Gisler N, Miro O, Martín-Sánchez FJ, Christ M, Gualandro DM, Twerenbold R, Gimenez MR, Keller DI, Buser A, Mueller C; APACE Investigators. Ratmann PD, et al. Among authors: gehrke j. Eur Heart J Acute Cardiovasc Care. 2022 Nov 30;11(11):834-840. doi: 10.1093/ehjacc/zuac120. Eur Heart J Acute Cardiovasc Care. 2022. PMID: 36179255
Cytosine base editing enables quadruple-edited allogeneic CART cells for T-ALL.
Diorio C, Murray R, Naniong M, Barrera L, Camblin A, Chukinas J, Coholan L, Edwards A, Fuller T, Gonzales C, Grupp SA, Ladd A, Le M, Messana A, Musenge F, Newman H, Poh YC, Poulin H, Ryan T, Shraim R, Tasian SK, Vincent T, Young L, Zhang Y, Ciaramella G, Gehrke J, Teachey DT. Diorio C, et al. Among authors: gehrke j. Blood. 2022 Aug 11;140(6):619-629. doi: 10.1182/blood.2022015825. Blood. 2022. PMID: 35560156 Free PMC article.
A 0/1h-algorithm using cardiac myosin-binding protein C for early diagnosis of myocardial infarction.
Kaier TE, Twerenbold R, Lopez-Ayala P, Nestelberger T, Boeddinghaus J, Alaour B, Huber IM, Zhi Y, Koechlin L, Wussler D, Wildi K, Shrestha S, Strebel I, Miro O, Martín-Sánchez JF, Christ M, Kawecki D, Keller DI, Rubini Gimenez M, Marber M, Mueller C; APACE Investigators. Kaier TE, et al. Eur Heart J Acute Cardiovasc Care. 2022 Jun 7;11(4):325-335. doi: 10.1093/ehjacc/zuac007. Eur Heart J Acute Cardiovasc Care. 2022. PMID: 35149868 Free PMC article.
Utility of Echocardiography in Patients With Suspected Acute Myocardial Infarction and Left Bundle-Branch Block.
Nestelberger T, Boeddinghaus J, Lopez Ayala P, Gehrke J, Twerenbold R, Cullen L, Mueller C; APACE, ADAPT, TRAPID‐AMI Investigators *. Nestelberger T, et al. Among authors: gehrke j. J Am Heart Assoc. 2021 Sep 21;10(18):e021262. doi: 10.1161/JAHA.121.021262. Epub 2021 Sep 13. J Am Heart Assoc. 2021. PMID: 34514839 Free PMC article. No abstract available.
Novel Criteria for the Observe-Zone of the ESC 0/1h-hs-cTnT Algorithm.
Lopez-Ayala P, Nestelberger T, Boeddinghaus J, Koechlin L, Ratmann PD, Strebel I, Gehrke J, Meier S, Walter J, Rubini Gimenez M, Mutschler E, Miró Ò, López-Barbeito B, Martín-Sánchez FJ, Rodríguez-Adrada E, Keller DI, Newby LK, Twerenbold R, Giannitsis E, Lindahl B, Mueller C; APACE and TRAPID-AMI Investigators†. Lopez-Ayala P, et al. Among authors: gehrke j. Circulation. 2021 Sep 7;144(10):773-787. doi: 10.1161/CIRCULATIONAHA.120.052982. Epub 2021 Aug 11. Circulation. 2021. PMID: 34376064 Free article.
Cardiovascular Biomarkers in the Early Discrimination of Type 2 Myocardial Infarction.
Nestelberger T, Boeddinghaus J, Lopez-Ayala P, Kaier TE, Marber M, Gysin V, Koechlin L, Sanchez AY, Giménez MR, Wussler D, Walter JE, Strebel I, Zimmermann T, Glarner N, Miró Ò, Martin-Sanchez FJ, Zehnder T, Twerenbold R, Keller DI, Mueller C; APACE Investigators. Nestelberger T, et al. JAMA Cardiol. 2021 Jul 1;6(7):771-780. doi: 10.1001/jamacardio.2021.0669. JAMA Cardiol. 2021. PMID: 33881449 Free PMC article.
Therapeutic base editing of human hematopoietic stem cells.
Zeng J, Wu Y, Ren C, Bonanno J, Shen AH, Shea D, Gehrke JM, Clement K, Luk K, Yao Q, Kim R, Wolfe SA, Manis JP, Pinello L, Joung JK, Bauer DE. Zeng J, et al. Among authors: gehrke jm. Nat Med. 2020 Apr;26(4):535-541. doi: 10.1038/s41591-020-0790-y. Epub 2020 Mar 16. Nat Med. 2020. PMID: 32284612 Free PMC article.
Directed evolution of adenine base editors with increased activity and therapeutic application.
Gaudelli NM, Lam DK, Rees HA, Solá-Esteves NM, Barrera LA, Born DA, Edwards A, Gehrke JM, Lee SJ, Liquori AJ, Murray R, Packer MS, Rinaldi C, Slaymaker IM, Yen J, Young LE, Ciaramella G. Gaudelli NM, et al. Among authors: gehrke jm. Nat Biotechnol. 2020 Jul;38(7):892-900. doi: 10.1038/s41587-020-0491-6. Epub 2020 Apr 13. Nat Biotechnol. 2020. PMID: 32284586
75 results