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iASPP, a previously unidentified regulator of desmosomes, prevents arrhythmogenic right ventricular cardiomyopathy (ARVC)-induced sudden death.
Notari M, Hu Y, Sutendra G, Dedeić Z, Lu M, Dupays L, Yavari A, Carr CA, Zhong S, Opel A, Tinker A, Clarke K, Watkins H, Ferguson DJ, Kelsell DP, de Noronha S, Sheppard MN, Hollinshead M, Mohun TJ, Lu X. Notari M, et al. Among authors: lu x, lu m. Proc Natl Acad Sci U S A. 2015 Mar 3;112(9):E973-81. doi: 10.1073/pnas.1408111112. Epub 2015 Feb 17. Proc Natl Acad Sci U S A. 2015. PMID: 25691752 Free PMC article.
iASPP oncoprotein is a key inhibitor of p53 conserved from worm to human.
Bergamaschi D, Samuels Y, O'Neil NJ, Trigiante G, Crook T, Hsieh JK, O'Connor DJ, Zhong S, Campargue I, Tomlinson ML, Kuwabara PE, Lu X. Bergamaschi D, et al. Among authors: lu x. Nat Genet. 2003 Feb;33(2):162-7. doi: 10.1038/ng1070. Epub 2003 Jan 13. Nat Genet. 2003. PMID: 12524540
ASPP--Apoptotic specific regulator of p53.
Liu ZJ, Lu X, Zhong S. Liu ZJ, et al. Among authors: lu x. Biochim Biophys Acta. 2005 Sep 25;1756(1):77-80. doi: 10.1016/j.bbcan.2005.08.002. Biochim Biophys Acta. 2005. PMID: 16139958 Review.
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