Morgan RA - Search Results

1

Tumor-infiltrating lymphocytes genetically engineered with an inducible gene encoding interleukin-12 for the immunotherapy of metastatic melanoma.

Zhang L, Morgan RA, Beane JD, Zheng Z, Dudley ME, Kassim SH, Nahvi AV, Ngo LT, Sherry RM, Phan GQ, Hughes MS, Kammula US, Feldman SA, Toomey MA, Kerkar SP, Restifo NP, Yang JC, Rosenberg SA. Zhang L, et al. Among authors: morgan ra. Clin Cancer Res. 2015 May 15;21(10):2278-88. doi: 10.1158/1078-0432.CCR-14-2085. Epub 2015 Feb 18. Clin Cancer Res. 2015. PMID: 25695689 Free PMC article. Clinical Trial.

2

Lymphocytes as cellular vehicles for gene therapy in mouse and man.

Culver K, Cornetta K, Morgan R, Morecki S, Aebersold P, Kasid A, Lotze M, Rosenberg SA, Anderson WF, Blaese RM. Culver K, et al. Proc Natl Acad Sci U S A. 1991 Apr 15;88(8):3155-9. doi: 10.1073/pnas.88.8.3155. Proc Natl Acad Sci U S A. 1991. PMID: 2014235 Free PMC article.

3

Gene transfer into humans--immunotherapy of patients with advanced melanoma, using tumor-infiltrating lymphocytes modified by retroviral gene transduction.

Rosenberg SA, Aebersold P, Cornetta K, Kasid A, Morgan RA, Moen R, Karson EM, Lotze MT, Yang JC, Topalian SL, et al. Rosenberg SA, et al. Among authors: morgan ra. N Engl J Med. 1990 Aug 30;323(9):570-8. doi: 10.1056/NEJM199008303230904. N Engl J Med. 1990. PMID: 2381442 Free article.

4

T lymphocyte-directed gene therapy for ADA- SCID: initial trial results after 4 years.

Blaese RM, Culver KW, Miller AD, Carter CS, Fleisher T, Clerici M, Shearer G, Chang L, Chiang Y, Tolstoshev P, Greenblatt JJ, Rosenberg SA, Klein H, Berger M, Mullen CA, Ramsey WJ, Muul L, Morgan RA, Anderson WF. Blaese RM, et al. Among authors: morgan ra. Science. 1995 Oct 20;270(5235):475-80. doi: 10.1126/science.270.5235.475. Science. 1995. PMID: 7570001 Clinical Trial.

5

Interleukin-2-transduced lymphocytes grow in an autocrine fashion and remain responsive to antigen.

Treisman J, Hwu P, Minamoto S, Shafer GE, Cowherd R, Morgan RA, Rosenberg SA. Treisman J, et al. Among authors: morgan ra. Blood. 1995 Jan 1;85(1):139-45. Blood. 1995. PMID: 7803791 Free article.

6

Ex vivo fibroblast transduction in rabbits results in long-term (>600 days) factor IX expression in a small percentage of animals.

Chen L, Nelson DM, Zheng Z, Morgan RA. Chen L, et al. Among authors: morgan ra. Hum Gene Ther. 1998 Nov 1;9(16):2341-51. doi: 10.1089/hum.1998.9.16-2341. Hum Gene Ther. 1998. PMID: 9829533

7

Inhibition of viral gene expression and replication in mosquito cells by dsRNA-triggered RNA interference.

Caplen NJ, Zheng Z, Falgout B, Morgan RA. Caplen NJ, et al. Among authors: morgan ra. Mol Ther. 2002 Aug;6(2):243-51. doi: 10.1006/mthe.2002.0652. Mol Ther. 2002. PMID: 12161191 Free article.

8

High efficiency TCR gene transfer into primary human lymphocytes affords avid recognition of melanoma tumor antigen glycoprotein 100 and does not alter the recognition of autologous melanoma antigens.

Morgan RA, Dudley ME, Yu YY, Zheng Z, Robbins PF, Theoret MR, Wunderlich JR, Hughes MS, Restifo NP, Rosenberg SA. Morgan RA, et al. J Immunol. 2003 Sep 15;171(6):3287-95. doi: 10.4049/jimmunol.171.6.3287. J Immunol. 2003. PMID: 12960359 Free PMC article.

9

Primary human lymphocytes transduced with NY-ESO-1 antigen-specific TCR genes recognize and kill diverse human tumor cell lines.

Zhao Y, Zheng Z, Robbins PF, Khong HT, Rosenberg SA, Morgan RA. Zhao Y, et al. Among authors: morgan ra. J Immunol. 2005 Apr 1;174(7):4415-23. doi: 10.4049/jimmunol.174.7.4415. J Immunol. 2005. PMID: 15778407 Free PMC article.

10

Transfer of a TCR gene derived from a patient with a marked antitumor response conveys highly active T-cell effector functions.

Hughes MS, Yu YY, Dudley ME, Zheng Z, Robbins PF, Li Y, Wunderlich J, Hawley RG, Moayeri M, Rosenberg SA, Morgan RA. Hughes MS, et al. Among authors: morgan ra. Hum Gene Ther. 2005 Apr;16(4):457-72. doi: 10.1089/hum.2005.16.457. Hum Gene Ther. 2005. PMID: 15871677 Free PMC article.

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