Kokuba H - Search Results

1

The E3 ligase synoviolin controls body weight and mitochondrial biogenesis through negative regulation of PGC-1β.

Fujita H, Yagishita N, Aratani S, Saito-Fujita T, Morota S, Yamano Y, Hansson MJ, Inazu M, Kokuba H, Sudo K, Sato E, Kawahara K, Nakajima F, Hasegawa D, Higuchi I, Sato T, Araya N, Usui C, Nishioka K, Nakatani Y, Maruyama I, Usui M, Hara N, Uchino H, Elmer E, Nishioka K, Nakajima T. Fujita H, et al. Among authors: kokuba h. EMBO J. 2015 Apr 15;34(8):1042-55. doi: 10.15252/embj.201489897. Epub 2015 Feb 19. EMBO J. 2015. PMID: 25698262 Free PMC article.

2

Targeting the integrated networks of aggresome formation, proteasome, and autophagy potentiates ER stress‑mediated cell death in multiple myeloma cells.

Moriya S, Komatsu S, Yamasaki K, Kawai Y, Kokuba H, Hirota A, Che XF, Inazu M, Gotoh A, Hiramoto M, Miyazawa K. Moriya S, et al. Among authors: kokuba h. Int J Oncol. 2015 Feb;46(2):474-86. doi: 10.3892/ijo.2014.2773. Epub 2014 Nov 24. Int J Oncol. 2015. PMID: 25422130 Free PMC article.

3

Harmol induces autophagy and subsequent apoptosis in U251MG human glioma cells through the downregulation of survivin.

Abe A, Kokuba H. Abe A, et al. Among authors: kokuba h. Oncol Rep. 2013 Apr;29(4):1333-42. doi: 10.3892/or.2013.2242. Epub 2013 Jan 18. Oncol Rep. 2013. PMID: 23338618

4

Macrolides sensitize EGFR-TKI-induced non-apoptotic cell death via blocking autophagy flux in pancreatic cancer cell lines.

Mukai S, Moriya S, Hiramoto M, Kazama H, Kokuba H, Che XF, Yokoyama T, Sakamoto S, Sugawara A, Sunazuka T, Ōmura S, Handa H, Itoi T, Miyazawa K. Mukai S, et al. Among authors: kokuba h. Int J Oncol. 2016 Jan;48(1):45-54. doi: 10.3892/ijo.2015.3237. Epub 2015 Nov 9. Int J Oncol. 2016. PMID: 26718641 Free PMC article.

5

Targeting bortezomib-induced aggresome formation using vinorelbine enhances the cytotoxic effect along with ER stress loading in breast cancer cell lines.

Miyahara K, Kazama H, Kokuba H, Komatsu S, Hirota A, Takemura J, Hirasawa K, Moriya S, Abe A, Hiramoto M, Ishikawa T, Miyazawa K. Miyahara K, et al. Among authors: kokuba h. Int J Oncol. 2016 Nov;49(5):1848-1858. doi: 10.3892/ijo.2016.3673. Epub 2016 Aug 29. Int J Oncol. 2016. PMID: 27601063 Free PMC article.

6

Visualization of ceramide channels in lysosomes following endogenous palmitoyl-ceramide accumulation as an initial step in the induction of necrosis.

Yamane M, Moriya S, Kokuba H. Yamane M, et al. Among authors: kokuba h. Biochem Biophys Rep. 2017 Mar 13;11:174-181. doi: 10.1016/j.bbrep.2017.02.010. eCollection 2017 Sep. Biochem Biophys Rep. 2017. PMID: 28955782 Free PMC article.

7

Amino acid starvation culture condition sensitizes EGFR-expressing cancer cell lines to gefitinib-mediated cytotoxicity by inducing atypical necroptosis.

Saito Y, Moriya S, Kazama H, Hirasawa K, Miyahara K, Kokuba H, Hino H, Kikuchi H, Takano N, Hiramoto M, Tsukahara K, Miyazawa K. Saito Y, et al. Among authors: kokuba h. Int J Oncol. 2018 Apr;52(4):1165-1177. doi: 10.3892/ijo.2018.4282. Epub 2018 Feb 23. Int J Oncol. 2018. PMID: 29484439 Free PMC article.

8

Vitamin K₂ induces non-apoptotic cell death along with autophagosome formation in breast cancer cell lines.

Miyazawa S, Moriya S, Kokuba H, Hino H, Takano N, Miyazawa K. Miyazawa S, et al. Among authors: kokuba h. Breast Cancer. 2020 Mar;27(2):225-235. doi: 10.1007/s12282-019-01012-y. Epub 2019 Oct 17. Breast Cancer. 2020. PMID: 31625014

9

Abemaciclib induces atypical cell death in cancer cells characterized by formation of cytoplasmic vacuoles derived from lysosomes.

Hino H, Iriyama N, Kokuba H, Kazama H, Moriya S, Takano N, Hiramoto M, Aizawa S, Miyazawa K. Hino H, et al. Among authors: kokuba h. Cancer Sci. 2020 Jun;111(6):2132-2145. doi: 10.1111/cas.14419. Cancer Sci. 2020. PMID: 32304130 Free PMC article.

10

Macrolide antibiotics enhance the antitumor effect of lansoprazole resulting in lysosomal membrane permeabilization‑associated cell death.

Takeda A, Takano N, Kokuba H, Hino H, Moriya S, Abe A, Hiramoto M, Tsukahara K, Miyazawa K. Takeda A, et al. Among authors: kokuba h. Int J Oncol. 2020 Dec;57(6):1280-1292. doi: 10.3892/ijo.2020.5138. Epub 2020 Oct 21. Int J Oncol. 2020. PMID: 33173988 Free PMC article.

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