Tonge PJ - Search Results

1

An ordered water channel in Staphylococcus aureus FabI: unraveling the mechanism of substrate recognition and reduction.

Schiebel J, Chang A, Merget B, Bommineni GR, Yu W, Spagnuolo LA, Baxter MV, Tareilus M, Tonge PJ, Kisker C, Sotriffer CA. Schiebel J, et al. Among authors: tonge pj. Biochemistry. 2015 Mar 17;54(10):1943-55. doi: 10.1021/bi5014358. Epub 2015 Mar 3. Biochemistry. 2015. PMID: 25706582 Free PMC article.

2

Structural basis and mechanism of enoyl reductase inhibition by triclosan.

Stewart MJ, Parikh S, Xiao G, Tonge PJ, Kisker C. Stewart MJ, et al. Among authors: tonge pj. J Mol Biol. 1999 Jul 23;290(4):859-65. doi: 10.1006/jmbi.1999.2907. J Mol Biol. 1999. PMID: 10398587

3

Stereoselectivity of enoyl-CoA hydratase results from preferential activation of one of two bound substrate conformers.

Bell AF, Feng Y, Hofstein HA, Parikh S, Wu J, Rudolph MJ, Kisker C, Whitty A, Tonge PJ. Bell AF, et al. Among authors: tonge pj. Chem Biol. 2002 Nov;9(11):1247-55. doi: 10.1016/s1074-5521(02)00263-6. Chem Biol. 2002. PMID: 12445775

4

Structure-activity studies of the inhibition of FabI, the enoyl reductase from Escherichia coli, by triclosan: kinetic analysis of mutant FabIs.

Sivaraman S, Zwahlen J, Bell AF, Hedstrom L, Tonge PJ. Sivaraman S, et al. Among authors: tonge pj. Biochemistry. 2003 Apr 22;42(15):4406-13. doi: 10.1021/bi0300229. Biochemistry. 2003. PMID: 12693936

5

Crystal structure of Mycobacterium tuberculosis MenB, a key enzyme in vitamin K2 biosynthesis.

Truglio JJ, Theis K, Feng Y, Gajda R, Machutta C, Tonge PJ, Kisker C. Truglio JJ, et al. Among authors: tonge pj. J Biol Chem. 2003 Oct 24;278(43):42352-60. doi: 10.1074/jbc.M307399200. Epub 2003 Aug 8. J Biol Chem. 2003. PMID: 12909628 Free article.

6

Structure of acyl carrier protein bound to FabI, the FASII enoyl reductase from Escherichia coli.

Rafi S, Novichenok P, Kolappan S, Stratton CF, Rawat R, Kisker C, Simmerling C, Tonge PJ. Rafi S, et al. Among authors: tonge pj. J Biol Chem. 2006 Dec 22;281(51):39285-39293. doi: 10.1074/jbc.M608758200. Epub 2006 Sep 29. J Biol Chem. 2006. PMID: 17012233 Free PMC article.

7

Lysine 190 is the catalytic base in MenF, the menaquinone-specific isochorismate synthase from Escherichia coli: implications for an enzyme family.

Kolappan S, Zwahlen J, Zhou R, Truglio JJ, Tonge PJ, Kisker C. Kolappan S, et al. Among authors: tonge pj. Biochemistry. 2007 Jan 30;46(4):946-53. doi: 10.1021/bi0608515. Biochemistry. 2007. PMID: 17240978

8

Structure and mechanism of MbtI, the salicylate synthase from Mycobacterium tuberculosis.

Zwahlen J, Kolappan S, Zhou R, Kisker C, Tonge PJ. Zwahlen J, et al. Among authors: tonge pj. Biochemistry. 2007 Jan 30;46(4):954-64. doi: 10.1021/bi060852x. Biochemistry. 2007. PMID: 17240979

9

Development of modern InhA inhibitors to combat drug resistant strains of Mycobacterium tuberculosis.

Tonge PJ, Kisker C, Slayden RA. Tonge PJ, et al. Curr Top Med Chem. 2007;7(5):489-98. doi: 10.2174/156802607780059781. Curr Top Med Chem. 2007. PMID: 17346194 Review.

10

Mechanism and inhibition of saFabI, the enoyl reductase from Staphylococcus aureus.

Xu H, Sullivan TJ, Sekiguchi J, Kirikae T, Ojima I, Stratton CF, Mao W, Rock FL, Alley MR, Johnson F, Walker SG, Tonge PJ. Xu H, et al. Among authors: tonge pj. Biochemistry. 2008 Apr 8;47(14):4228-36. doi: 10.1021/bi800023a. Epub 2008 Mar 13. Biochemistry. 2008. PMID: 18335995 Free PMC article.

Save citations to file

Email citations

Send citations to clipboard

Add to Collections

Add to My Bibliography

Create a file for external citation management software

Your saved search

Your RSS Feed

My Custom Filters

Publication date

Text availability

Article attribute

Article type

Article Language

Species

Sex

Age

Other

185 results

Search Page

Filters