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Complement C1q-induced activation of β-catenin signalling causes hypertensive arterial remodelling.
Sumida T, Naito AT, Nomura S, Nakagawa A, Higo T, Hashimoto A, Okada K, Sakai T, Ito M, Yamaguchi T, Oka T, Akazawa H, Lee JK, Minamino T, Offermanns S, Noda T, Botto M, Kobayashi Y, Morita H, Manabe I, Nagai T, Shiojima I, Komuro I. Sumida T, et al. Among authors: oka t. Nat Commun. 2015 Feb 26;6:6241. doi: 10.1038/ncomms7241. Nat Commun. 2015. PMID: 25716000 Free PMC article.
Csx/Nkx2-5 is required for homeostasis and survival of cardiac myocytes in the adult heart.
Toko H, Zhu W, Takimoto E, Shiojima I, Hiroi Y, Zou Y, Oka T, Akazawa H, Mizukami M, Sakamoto M, Terasaki F, Kitaura Y, Takano H, Nagai T, Nagai R, Komuro I. Toko H, et al. Among authors: oka t. J Biol Chem. 2002 Jul 5;277(27):24735-43. doi: 10.1074/jbc.M107669200. Epub 2002 Mar 11. J Biol Chem. 2002. PMID: 11889119 Free article.
Ca2+/calmodulin-dependent kinase IIdelta causes heart failure by accumulation of p53 in dilated cardiomyopathy.
Toko H, Takahashi H, Kayama Y, Oka T, Minamino T, Okada S, Morimoto S, Zhan DY, Terasaki F, Anderson ME, Inoue M, Yao A, Nagai R, Kitaura Y, Sasaguri T, Komuro I. Toko H, et al. Among authors: oka t. Circulation. 2010 Aug 31;122(9):891-9. doi: 10.1161/CIRCULATIONAHA.109.935296. Epub 2010 Aug 16. Circulation. 2010. PMID: 20713897 Free PMC article.
Rationale and design of a study to evaluate effects of pitavastatin on Japanese patients with chronic heart failure: the pitavastatin heart failure study (PEARL study).
Mizuma H, Inoue T, Takano H, Shindo S, Oka T, Fujimatsu D, Kuwabara Y, Node K, Komuro I; PEARL Study Investigators. Mizuma H, et al. Among authors: oka t. Int J Cardiol. 2012 Apr 19;156(2):144-7. doi: 10.1016/j.ijcard.2010.10.022. Epub 2010 Nov 13. Int J Cardiol. 2012. PMID: 21075465 Clinical Trial.
Agonist-independent constitutive activity of angiotensin II receptor promotes cardiac remodeling in mice.
Yasuda N, Akazawa H, Ito K, Shimizu I, Kudo-Sakamoto Y, Yabumoto C, Yano M, Yamamoto R, Ozasa Y, Minamino T, Naito AT, Oka T, Shiojima I, Tamura K, Umemura S, Paradis P, Nemer M, Komuro I. Yasuda N, et al. Among authors: oka t. Hypertension. 2012 Mar;59(3):627-33. doi: 10.1161/HYPERTENSIONAHA.111.175208. Epub 2012 Jan 30. Hypertension. 2012. PMID: 22291447
2,889 results