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Lysosomal calcium signalling regulates autophagy through calcineurin and ​TFEB.
Medina DL, Di Paola S, Peluso I, Armani A, De Stefani D, Venditti R, Montefusco S, Scotto-Rosato A, Prezioso C, Forrester A, Settembre C, Wang W, Gao Q, Xu H, Sandri M, Rizzuto R, De Matteis MA, Ballabio A. Medina DL, et al. Among authors: ballabio a. Nat Cell Biol. 2015 Mar;17(3):288-99. doi: 10.1038/ncb3114. Nat Cell Biol. 2015. PMID: 25720963 Free PMC article.
A block of autophagy in lysosomal storage disorders.
Settembre C, Fraldi A, Jahreiss L, Spampanato C, Venturi C, Medina D, de Pablo R, Tacchetti C, Rubinsztein DC, Ballabio A. Settembre C, et al. Among authors: ballabio a. Hum Mol Genet. 2008 Jan 1;17(1):119-29. doi: 10.1093/hmg/ddm289. Epub 2007 Oct 3. Hum Mol Genet. 2008. PMID: 17913701
Lysosomal storage diseases as disorders of autophagy.
Settembre C, Fraldi A, Rubinsztein DC, Ballabio A. Settembre C, et al. Among authors: ballabio a. Autophagy. 2008 Jan;4(1):113-4. doi: 10.4161/auto.5227. Epub 2007 Oct 30. Autophagy. 2008. PMID: 18000397
A gene network regulating lysosomal biogenesis and function.
Sardiello M, Palmieri M, di Ronza A, Medina DL, Valenza M, Gennarino VA, Di Malta C, Donaudy F, Embrione V, Polishchuk RS, Banfi S, Parenti G, Cattaneo E, Ballabio A. Sardiello M, et al. Among authors: ballabio a. Science. 2009 Jul 24;325(5939):473-7. doi: 10.1126/science.1174447. Epub 2009 Jun 25. Science. 2009. PMID: 19556463
Defective CFTR induces aggresome formation and lung inflammation in cystic fibrosis through ROS-mediated autophagy inhibition.
Luciani A, Villella VR, Esposito S, Brunetti-Pierri N, Medina D, Settembre C, Gavina M, Pulze L, Giardino I, Pettoello-Mantovani M, D'Apolito M, Guido S, Masliah E, Spencer B, Quaratino S, Raia V, Ballabio A, Maiuri L. Luciani A, et al. Among authors: ballabio a. Nat Cell Biol. 2010 Sep;12(9):863-75. doi: 10.1038/ncb2090. Epub 2010 Aug 15. Nat Cell Biol. 2010. PMID: 20711182
Cystic fibrosis: a disorder with defective autophagy.
Luciani A, Villella VR, Esposito S, Brunetti-Pierri N, Medina DL, Settembre C, Gavina M, Raia V, Ballabio A, Maiuri L. Luciani A, et al. Among authors: ballabio a. Autophagy. 2011 Jan;7(1):104-6. doi: 10.4161/auto.7.1.13987. Epub 2011 Jan 1. Autophagy. 2011. PMID: 21048426
TFEB links autophagy to lysosomal biogenesis.
Settembre C, Di Malta C, Polito VA, Garcia Arencibia M, Vetrini F, Erdin S, Erdin SU, Huynh T, Medina D, Colella P, Sardiello M, Rubinsztein DC, Ballabio A. Settembre C, et al. Among authors: ballabio a. Science. 2011 Jun 17;332(6036):1429-33. doi: 10.1126/science.1204592. Epub 2011 May 26. Science. 2011. PMID: 21617040 Free PMC article.
Transcriptional activation of lysosomal exocytosis promotes cellular clearance.
Medina DL, Fraldi A, Bouche V, Annunziata F, Mansueto G, Spampanato C, Puri C, Pignata A, Martina JA, Sardiello M, Palmieri M, Polishchuk R, Puertollano R, Ballabio A. Medina DL, et al. Among authors: ballabio a. Dev Cell. 2011 Sep 13;21(3):421-30. doi: 10.1016/j.devcel.2011.07.016. Epub 2011 Sep 1. Dev Cell. 2011. PMID: 21889421 Free PMC article.
468 results