Sousa GL - Search Results

1

TREM2 deficiency eliminates TREM2+ inflammatory macrophages and ameliorates pathology in Alzheimer's disease mouse models.

Jay TR, Miller CM, Cheng PJ, Graham LC, Bemiller S, Broihier ML, Xu G, Margevicius D, Karlo JC, Sousa GL, Cotleur AC, Butovsky O, Bekris L, Staugaitis SM, Leverenz JB, Pimplikar SW, Landreth GE, Howell GR, Ransohoff RM, Lamb BT. Jay TR, et al. Among authors: sousa gl. J Exp Med. 2015 Mar 9;212(3):287-95. doi: 10.1084/jem.20142322. Epub 2015 Mar 2. J Exp Med. 2015. PMID: 25732305 Free PMC article.

2

Combinatorial targeting of early pathways profoundly inhibits neurodegeneration in a mouse model of glaucoma.

Howell GR, MacNicoll KH, Braine CE, Soto I, Macalinao DG, Sousa GL, John SW. Howell GR, et al. Among authors: sousa gl. Neurobiol Dis. 2014 Nov;71:44-52. doi: 10.1016/j.nbd.2014.07.016. Epub 2014 Aug 15. Neurobiol Dis. 2014. PMID: 25132557 Free PMC article.

3

Inhibition of monocyte-like cell extravasation protects from neurodegeneration in DBA/2J glaucoma.

Williams PA, Braine CE, Kizhatil K, Foxworth NE, Tolman NG, Harder JM, Scott RA, Sousa GL, Panitch A, Howell GR, John SWM. Williams PA, et al. Among authors: sousa gl. Mol Neurodegener. 2019 Jan 22;14(1):6. doi: 10.1186/s13024-018-0303-3. Mol Neurodegener. 2019. PMID: 30670050 Free PMC article.

4

Early immune responses are independent of RGC dysfunction in glaucoma with complement component C3 being protective.

Harder JM, Braine CE, Williams PA, Zhu X, MacNicoll KH, Sousa GL, Buchanan RA, Smith RS, Libby RT, Howell GR, John SWM. Harder JM, et al. Among authors: sousa gl. Proc Natl Acad Sci U S A. 2017 May 9;114(19):E3839-E3848. doi: 10.1073/pnas.1608769114. Epub 2017 Apr 26. Proc Natl Acad Sci U S A. 2017. PMID: 28446616 Free PMC article.

5

Molecular clustering identifies complement and endothelin induction as early events in a mouse model of glaucoma.

Howell GR, Macalinao DG, Sousa GL, Walden M, Soto I, Kneeland SC, Barbay JM, King BL, Marchant JK, Hibbs M, Stevens B, Barres BA, Clark AF, Libby RT, John SW. Howell GR, et al. Among authors: sousa gl. J Clin Invest. 2011 Apr;121(4):1429-44. doi: 10.1172/JCI44646. Epub 2011 Mar 7. J Clin Invest. 2011. PMID: 21383504 Free PMC article.

6

Radiation treatment inhibits monocyte entry into the optic nerve head and prevents neuronal damage in a mouse model of glaucoma.

Howell GR, Soto I, Zhu X, Ryan M, Macalinao DG, Sousa GL, Caddle LB, MacNicoll KH, Barbay JM, Porciatti V, Anderson MG, Smith RS, Clark AF, Libby RT, John SW. Howell GR, et al. Among authors: sousa gl. J Clin Invest. 2012 Apr;122(4):1246-61. doi: 10.1172/JCI61135. Epub 2012 Mar 19. J Clin Invest. 2012. PMID: 22426214 Free PMC article.

7

Retinal ganglion cell dendritic atrophy in DBA/2J glaucoma.

Williams PA, Howell GR, Barbay JM, Braine CE, Sousa GL, John SW, Morgan JE. Williams PA, et al. Among authors: sousa gl. PLoS One. 2013 Aug 19;8(8):e72282. doi: 10.1371/journal.pone.0072282. eCollection 2013. PLoS One. 2013. PMID: 23977271 Free PMC article.

8

Stimulation of a protease targeting the LRIM1/APL1C complex reveals specificity in complement-like pathway activation in Anopheles gambiae.

Reyes Ruiz VM, Sousa GL, Sneed SD, Farrant KV, Christophides GK, Povelones M. Reyes Ruiz VM, et al. Among authors: sousa gl. PLoS One. 2019 Apr 8;14(4):e0214753. doi: 10.1371/journal.pone.0214753. eCollection 2019. PLoS One. 2019. PMID: 30958840 Free PMC article.

9

The CLIP-domain serine protease CLIPC9 regulates melanization downstream of SPCLIP1, CLIPA8, and CLIPA28 in the malaria vector Anopheles gambiae.

Sousa GL, Bishnoi R, Baxter RHG, Povelones M. Sousa GL, et al. PLoS Pathog. 2020 Oct 12;16(10):e1008985. doi: 10.1371/journal.ppat.1008985. eCollection 2020 Oct. PLoS Pathog. 2020. PMID: 33045027 Free PMC article.

10

Solution structure, glycan specificity and of phenol oxidase inhibitory activity of Anopheles C-type lectins CTL4 and CTLMA2.

Bishnoi R, Sousa GL, Contet A, Day CJ, Hou CD, Profitt LA, Singla D, Jennings MP, Valentine AM, Povelones M, Baxter RHG. Bishnoi R, et al. Among authors: sousa gl. Sci Rep. 2019 Oct 23;9(1):15191. doi: 10.1038/s41598-019-51353-z. Sci Rep. 2019. PMID: 31645596 Free PMC article.

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