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Targeted ablation of the Pde6h gene in mice reveals cross-species differences in cone and rod phototransduction protein isoform inventory.
Brennenstuhl C, Tanimoto N, Burkard M, Wagner R, Bolz S, Trifunovic D, Kabagema-Bilan C, Paquet-Durand F, Beck SC, Huber G, Seeliger MW, Ruth P, Wissinger B, Lukowski R. Brennenstuhl C, et al. Among authors: beck sc. J Biol Chem. 2015 Apr 17;290(16):10242-55. doi: 10.1074/jbc.M114.611921. Epub 2015 Mar 4. J Biol Chem. 2015. PMID: 25739440 Free PMC article.
A key role for cyclic nucleotide gated (CNG) channels in cGMP-related retinitis pigmentosa.
Paquet-Durand F, Beck S, Michalakis S, Goldmann T, Huber G, Mühlfriedel R, Trifunović D, Fischer MD, Fahl E, Duetsch G, Becirovic E, Wolfrum U, van Veen T, Biel M, Tanimoto N, Seeliger MW. Paquet-Durand F, et al. Hum Mol Genet. 2011 Mar 1;20(5):941-7. doi: 10.1093/hmg/ddq539. Epub 2010 Dec 10. Hum Mol Genet. 2011. PMID: 21149284
In vivo analysis of cone survival in mice.
Beck SC, Schaeferhoff K, Michalakis S, Fischer MD, Huber G, Rieger N, Riess O, Wissinger B, Biel M, Bonin M, Seeliger MW, Tanimoto N. Beck SC, et al. Invest Ophthalmol Vis Sci. 2010 Jan;51(1):493-7. doi: 10.1167/iovs.09-4003. Epub 2009 Sep 8. Invest Ophthalmol Vis Sci. 2010. PMID: 19737879
Restoration of cone vision in the CNGA3-/- mouse model of congenital complete lack of cone photoreceptor function.
Michalakis S, Mühlfriedel R, Tanimoto N, Krishnamoorthy V, Koch S, Fischer MD, Becirovic E, Bai L, Huber G, Beck SC, Fahl E, Büning H, Paquet-Durand F, Zong X, Gollisch T, Biel M, Seeliger MW. Michalakis S, et al. Among authors: beck sc. Mol Ther. 2010 Dec;18(12):2057-63. doi: 10.1038/mt.2010.149. Epub 2010 Jul 13. Mol Ther. 2010. PMID: 20628362 Free PMC article.
Retinitis pigmentosa: impact of different Pde6a point mutations on the disease phenotype.
Sothilingam V, Garcia Garrido M, Jiao K, Buena-Atienza E, Sahaboglu A, Trifunović D, Balendran S, Koepfli T, Mühlfriedel R, Schön C, Biel M, Heckmann A, Beck SC, Michalakis S, Wissinger B, Seeliger MW, Paquet-Durand F. Sothilingam V, et al. Among authors: beck sc. Hum Mol Genet. 2015 Oct 1;24(19):5486-99. doi: 10.1093/hmg/ddv275. Epub 2015 Jul 17. Hum Mol Genet. 2015. PMID: 26188004
Accessory heterozygous mutations in cone photoreceptor CNGA3 exacerbate CNG channel-associated retinopathy.
Burkard M, Kohl S, Krätzig T, Tanimoto N, Brennenstuhl C, Bausch AE, Junger K, Reuter P, Sothilingam V, Beck SC, Huber G, Ding XQ, Mayer AK, Baumann B, Weisschuh N, Zobor D, Hahn GA, Kellner U, Venturelli S, Becirovic E, Charbel Issa P, Koenekoop RK, Rudolph G, Heckenlively J, Sieving P, Weleber RG, Hamel C, Zong X, Biel M, Lukowski R, Seeliger MW, Michalakis S, Wissinger B, Ruth P. Burkard M, et al. Among authors: beck sc. J Clin Invest. 2018 Dec 3;128(12):5663-5675. doi: 10.1172/JCI96098. Epub 2018 Nov 12. J Clin Invest. 2018. PMID: 30418171 Free PMC article.
Induction of STAT3-related genes in fast degenerating cone photoreceptors of cpfl1 mice.
Schaeferhoff K, Michalakis S, Tanimoto N, Fischer MD, Becirovic E, Beck SC, Huber G, Rieger N, Riess O, Wissinger B, Biel M, Seeliger MW, Bonin M. Schaeferhoff K, et al. Among authors: beck sc. Cell Mol Life Sci. 2010 Sep;67(18):3173-86. doi: 10.1007/s00018-010-0376-9. Epub 2010 May 14. Cell Mol Life Sci. 2010. PMID: 20467778 Free PMC article.
Novel rodent models for macular research.
Huber G, Heynen S, Imsand C, vom Hagen F, Muehlfriedel R, Tanimoto N, Feng Y, Hammes HP, Grimm C, Peichl L, Seeliger MW, Beck SC. Huber G, et al. Among authors: beck sc. PLoS One. 2010 Oct 15;5(10):e13403. doi: 10.1371/journal.pone.0013403. PLoS One. 2010. PMID: 20976212 Free PMC article.
93 results