Dror RO - Search Results

1

Structural biology. Structural basis for chemokine recognition and activation of a viral G protein-coupled receptor.

Burg JS, Ingram JR, Venkatakrishnan AJ, Jude KM, Dukkipati A, Feinberg EN, Angelini A, Waghray D, Dror RO, Ploegh HL, Garcia KC. Burg JS, et al. Among authors: dror ro. Science. 2015 Mar 6;347(6226):1113-7. doi: 10.1126/science.aaa5026. Science. 2015. PMID: 25745166 Free PMC article.

2

The dynamic process of β(2)-adrenergic receptor activation.

Nygaard R, Zou Y, Dror RO, Mildorf TJ, Arlow DH, Manglik A, Pan AC, Liu CW, Fung JJ, Bokoch MP, Thian FS, Kobilka TS, Shaw DE, Mueller L, Prosser RS, Kobilka BK. Nygaard R, et al. Among authors: dror ro. Cell. 2013 Jan 31;152(3):532-42. doi: 10.1016/j.cell.2013.01.008. Cell. 2013. PMID: 23374348 Free PMC article.

3

SIGNAL TRANSDUCTION. Structural basis for nucleotide exchange in heterotrimeric G proteins.

Dror RO, Mildorf TJ, Hilger D, Manglik A, Borhani DW, Arlow DH, Philippsen A, Villanueva N, Yang Z, Lerch MT, Hubbell WL, Kobilka BK, Sunahara RK, Shaw DE. Dror RO, et al. Science. 2015 Jun 19;348(6241):1361-5. doi: 10.1126/science.aaa5264. Science. 2015. PMID: 26089515 Free PMC article.

4

Structural insights into µ-opioid receptor activation.

Huang W, Manglik A, Venkatakrishnan AJ, Laeremans T, Feinberg EN, Sanborn AL, Kato HE, Livingston KE, Thorsen TS, Kling RC, Granier S, Gmeiner P, Husbands SM, Traynor JR, Weis WI, Steyaert J, Dror RO, Kobilka BK. Huang W, et al. Among authors: dror ro. Nature. 2015 Aug 20;524(7565):315-21. doi: 10.1038/nature14886. Epub 2015 Aug 5. Nature. 2015. PMID: 26245379 Free PMC article.

5

GPCR Dynamics: Structures in Motion.

Latorraca NR, Venkatakrishnan AJ, Dror RO. Latorraca NR, et al. Among authors: dror ro. Chem Rev. 2017 Jan 11;117(1):139-155. doi: 10.1021/acs.chemrev.6b00177. Epub 2016 Sep 13. Chem Rev. 2017. PMID: 27622975 Free article. Review.

6

Crystal Structure of an LSD-Bound Human Serotonin Receptor.

Wacker D, Wang S, McCorvy JD, Betz RM, Venkatakrishnan AJ, Levit A, Lansu K, Schools ZL, Che T, Nichols DE, Shoichet BK, Dror RO, Roth BL. Wacker D, et al. Among authors: dror ro. Cell. 2017 Jan 26;168(3):377-389.e12. doi: 10.1016/j.cell.2016.12.033. Cell. 2017. PMID: 28129538 Free PMC article.

7

Mechanism of Substrate Translocation in an Alternating Access Transporter.

Latorraca NR, Fastman NM, Venkatakrishnan AJ, Frommer WB, Dror RO, Feng L. Latorraca NR, et al. Among authors: dror ro. Cell. 2017 Mar 23;169(1):96-107.e12. doi: 10.1016/j.cell.2017.03.010. Cell. 2017. PMID: 28340354 Free PMC article.

8

Mechanism of intracellular allosteric β₂AR antagonist revealed by X-ray crystal structure.

Liu X, Ahn S, Kahsai AW, Meng KC, Latorraca NR, Pani B, Venkatakrishnan AJ, Masoudi A, Weis WI, Dror RO, Chen X, Lefkowitz RJ, Kobilka BK. Liu X, et al. Among authors: dror ro. Nature. 2017 Aug 24;548(7668):480-484. doi: 10.1038/nature23652. Epub 2017 Aug 16. Nature. 2017. PMID: 28813418 Free PMC article.

9

D₄ dopamine receptor high-resolution structures enable the discovery of selective agonists.

Wang S, Wacker D, Levit A, Che T, Betz RM, McCorvy JD, Venkatakrishnan AJ, Huang XP, Dror RO, Shoichet BK, Roth BL. Wang S, et al. Among authors: dror ro. Science. 2017 Oct 20;358(6361):381-386. doi: 10.1126/science.aan5468. Science. 2017. PMID: 29051383 Free PMC article.

10

Structural basis for σ₁ receptor ligand recognition.

Schmidt HR, Betz RM, Dror RO, Kruse AC. Schmidt HR, et al. Among authors: dror ro. Nat Struct Mol Biol. 2018 Oct;25(10):981-987. doi: 10.1038/s41594-018-0137-2. Epub 2018 Oct 5. Nat Struct Mol Biol. 2018. PMID: 30291362 Free PMC article.

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