Arnold ME - Search Results

1

Development and validation of a liquid chromatography tandem mass spectrometry assay for the quantitation of a protein therapeutic in cynomolgus monkey serum.

Zhao Y, Liu G, Angeles A, Hamuro LL, Trouba KJ, Wang B, Pillutla RC, DeSilva BS, Arnold ME, Shen JX. Zhao Y, et al. Among authors: arnold me. J Chromatogr B Analyt Technol Biomed Life Sci. 2015 Apr 15;988:81-7. doi: 10.1016/j.jchromb.2015.02.007. Epub 2015 Feb 16. J Chromatogr B Analyt Technol Biomed Life Sci. 2015. PMID: 25756208

2

Strategy of accelerated method development for high-throughput bioanalytical assays using ultra high-performance liquid chromatography coupled with mass spectrometry.

Liu G, Snapp HM, Ji QC, Arnold ME. Liu G, et al. Among authors: arnold me. Anal Chem. 2009 Nov 15;81(22):9225-32. doi: 10.1021/ac901316w. Anal Chem. 2009. PMID: 19856950

3

Identifying, evaluating, and controlling bioanalytical risks resulting from nonuniform matrix ion suppression/enhancement and nonlinear liquid chromatography-mass spectrometry assay response.

Liu G, Ji QC, Arnold ME. Liu G, et al. Among authors: arnold me. Anal Chem. 2010 Dec 1;82(23):9671-7. doi: 10.1021/ac1013018. Epub 2010 Nov 1. Anal Chem. 2010. PMID: 21038862

4

Fully validated LC-MS/MS assay for the simultaneous quantitation of coadministered therapeutic antibodies in cynomolgus monkey serum.

Jiang H, Zeng J, Titsch C, Voronin K, Akinsanya B, Luo L, Shen H, Desai DD, Allentoff A, Aubry AF, Desilva BS, Arnold ME. Jiang H, et al. Among authors: arnold me. Anal Chem. 2013 Oct 15;85(20):9859-67. doi: 10.1021/ac402420v. Epub 2013 Sep 26. Anal Chem. 2013. PMID: 24024648

5

Bioanalysis of propylparaben and p-hydroxybenzoic acid, and their sulfate conjugates in rat plasma by liquid chromatography-tandem mass spectrometry.

Zhao Y, Liu G, Shen H, Shen JX, Aubry AF, Sivaraman L, Arnold ME. Zhao Y, et al. Among authors: arnold me. J Chromatogr B Analyt Technol Biomed Life Sci. 2014 Feb 1;947-948:68-74. doi: 10.1016/j.jchromb.2013.12.012. Epub 2013 Dec 24. J Chromatogr B Analyt Technol Biomed Life Sci. 2014. PMID: 24412689

6

A novel and cost effective method of removing excess albumin from plasma/serum samples and its impacts on LC-MS/MS bioanalysis of therapeutic proteins.

Liu G, Zhao Y, Angeles A, Hamuro LL, Arnold ME, Shen JX. Liu G, et al. Among authors: arnold me. Anal Chem. 2014 Aug 19;86(16):8336-43. doi: 10.1021/ac501837t. Epub 2014 Aug 8. Anal Chem. 2014. PMID: 25083595

7

A UHPLC-MS/MS bioanalytical assay for the determination of BMS-911543, a JAK2 inhibitor, in human plasma.

Liu J, Yuan L, Liu G, Shen JX, Aubry AF, Arnold ME, Ji QC. Liu J, et al. Among authors: arnold me. J Chromatogr B Analyt Technol Biomed Life Sci. 2015 Jun 1;991:85-91. doi: 10.1016/j.jchromb.2015.04.013. Epub 2015 Apr 17. J Chromatogr B Analyt Technol Biomed Life Sci. 2015. PMID: 25930207

8

Challenges and solutions in the bioanalysis of BMS-986094 and its metabolites including a highly polar, active nucleoside triphosphate in plasma and tissues using LC-MS/MS.

Liu A, Lute J, Gu H, Wang B, Trouba KJ, Arnold ME, Aubry AF, Wang J. Liu A, et al. Among authors: arnold me. J Chromatogr B Analyt Technol Biomed Life Sci. 2015 Sep 1;1000:29-40. doi: 10.1016/j.jchromb.2015.07.006. Epub 2015 Jul 13. J Chromatogr B Analyt Technol Biomed Life Sci. 2015. PMID: 26209768

9

Liquid chromatography coupled with tandem mass spectrometry for the bioanalysis of proteins in drug development: practical considerations in assay development and validation.

Liu G, Ji QC, Dodge R, Sun H, Shuster D, Zhao Q, Arnold M. Liu G, et al. J Chromatogr A. 2013 Apr 5;1284:155-62. doi: 10.1016/j.chroma.2013.02.016. Epub 2013 Feb 13. J Chromatogr A. 2013. PMID: 23466204

10

A rugged and accurate liquid chromatography-tandem mass spectrometry method for quantitative determination of BMS-790052 in plasma.

Jiang H, Zeng J, Deng Y, Xia YQ, Ouyang Z, Jemal M, Salcedo TW, Arnold ME. Jiang H, et al. Among authors: arnold me. J Chromatogr B Analyt Technol Biomed Life Sci. 2011 Jul 15;879(22):2064-72. doi: 10.1016/j.jchromb.2011.05.036. Epub 2011 May 30. J Chromatogr B Analyt Technol Biomed Life Sci. 2011. PMID: 21704571

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