Schenone S - Search Results

1

SRC family kinase (SFK) inhibition reduces rhabdomyosarcoma cell growth in vitro and in vivo and triggers p38 MAP kinase-mediated differentiation.

Casini N, Forte IM, Mastrogiovanni G, Pentimalli F, Angelucci A, Festuccia C, Tomei V, Ceccherini E, Di Marzo D, Schenone S, Botta M, Giordano A, Indovina P. Casini N, et al. Among authors: schenone s. Oncotarget. 2015 May 20;6(14):12421-35. doi: 10.18632/oncotarget.3043. Oncotarget. 2015. PMID: 25762618 Free PMC article.

2

Pyrazolo[3,4-d]pyrimidines endowed with antiproliferative activity on ductal infiltrating carcinoma cells.

Carraro F, Pucci A, Naldini A, Schenone S, Bruno O, Ranise A, Bondavalli F, Brullo C, Fossa P, Menozzi G, Mosti L, Manetti F, Botta M. Carraro F, et al. Among authors: schenone s. J Med Chem. 2004 Mar 25;47(7):1595-8. doi: 10.1021/jm034257u. J Med Chem. 2004. PMID: 15027847

3

New pyrazolo[3,4-d]pyrimidines endowed with A431 antiproliferative activity and inhibitory properties of Src phosphorylation.

Schenone S, Bruno O, Ranise A, Bondavalli F, Brullo C, Fossa P, Mosti L, Menozzi G, Carraro F, Naldini A, Bernini C, Manetti F, Botta M. Schenone S, et al. Bioorg Med Chem Lett. 2004 May 17;14(10):2511-7. doi: 10.1016/j.bmcl.2004.03.013. Bioorg Med Chem Lett. 2004. PMID: 15109642

4

Antiproliferative activity of new 1-aryl-4-amino-1H-pyrazolo[3,4-d]pyrimidine derivatives toward the human epidermoid carcinoma A431 cell line.

Schenone S, Bruno O, Bondavalli F, Ranise A, Mosti L, Menozzi G, Fossa P, Donnini S, Santoro A, Ziche M, Manetti F, Botta M. Schenone S, et al. Eur J Med Chem. 2004 Nov;39(11):939-46. doi: 10.1016/j.ejmech.2004.07.010. Eur J Med Chem. 2004. PMID: 15501543

5

Pyrazolo[3,4-d]pyrimidines as potent antiproliferative and proapoptotic agents toward A431 and 8701-BC cells in culture via inhibition of c-Src phosphorylation.

Carraro F, Naldini A, Pucci A, Locatelli GA, Maga G, Schenone S, Bruno O, Ranise A, Bondavalli F, Brullo C, Fossa P, Menozzi G, Mosti L, Modugno M, Tintori C, Manetti F, Botta M. Carraro F, et al. Among authors: schenone s. J Med Chem. 2006 Mar 9;49(5):1549-61. doi: 10.1021/jm050603r. J Med Chem. 2006. PMID: 16509573

6

A combination of docking/dynamics simulations and pharmacophoric modeling to discover new dual c-Src/Abl kinase inhibitors.

Manetti F, Locatelli GA, Maga G, Schenone S, Modugno M, Forli S, Corelli F, Botta M. Manetti F, et al. Among authors: schenone s. J Med Chem. 2006 Jun 1;49(11):3278-86. doi: 10.1021/jm060236z. J Med Chem. 2006. PMID: 16722646

7

Pyrazolo[3,4-d]pyrimidines c-Src inhibitors reduce epidermal growth factor-induced migration in prostate cancer cells.

Angelucci A, Schenone S, Gravina GL, Muzi P, Festuccia C, Vicentini C, Botta M, Bologna M. Angelucci A, et al. Among authors: schenone s. Eur J Cancer. 2006 Nov;42(16):2838-45. doi: 10.1016/j.ejca.2006.06.024. Epub 2006 Sep 14. Eur J Cancer. 2006. PMID: 16973347

8

Pyrazolo-pyrimidine-derived c-Src inhibitor reduces angiogenesis and survival of squamous carcinoma cells by suppressing vascular endothelial growth factor production and signaling.

Donnini S, Monti M, Castagnini C, Solito R, Botta M, Schenone S, Giachetti A, Ziche M. Donnini S, et al. Among authors: schenone s. Int J Cancer. 2007 Mar 1;120(5):995-1004. doi: 10.1002/ijc.22410. Int J Cancer. 2007. PMID: 17131343

9

Inhibition of Bcr-Abl phosphorylation and induction of apoptosis by pyrazolo[3,4-d]pyrimidines in human leukemia cells.

Manetti F, Pucci A, Magnani M, Locatelli GA, Brullo C, Naldini A, Schenone S, Maga G, Carraro F, Botta M. Manetti F, et al. Among authors: schenone s. ChemMedChem. 2007 Mar;2(3):343-53. doi: 10.1002/cmdc.200600214. ChemMedChem. 2007. PMID: 17295370

10

Last findings on dual inhibitors of abl and SRC tyrosine-kinases.

Schenone S, Manetti F, Botta M. Schenone S, et al. Mini Rev Med Chem. 2007 Feb;7(2):191-201. doi: 10.2174/138955707779802598. Mini Rev Med Chem. 2007. PMID: 17305593 Review.

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