Kharasch ED - Search Results

1

Opioid Half-lives and Hemlines: The Long and Short of Fashion.

Kharasch ED. Kharasch ED. Anesthesiology. 2015 May;122(5):969-70. doi: 10.1097/ALN.0000000000000634. Anesthesiology. 2015. PMID: 25768861 Free PMC article. No abstract available.

2

Simultaneous assessment of drug interactions with low- and high-extraction opioids: application to parecoxib effects on the pharmacokinetics and pharmacodynamics of fentanyl and alfentanil.

Ibrahim AE, Feldman J, Karim A, Kharasch ED. Ibrahim AE, et al. Among authors: kharasch ed. Anesthesiology. 2003 Apr;98(4):853-61. doi: 10.1097/00000542-200304000-00011. Anesthesiology. 2003. PMID: 12657846 Free article. Clinical Trial.

3

Influence of hepatic and intestinal cytochrome P4503A activity on the acute disposition and effects of oral transmucosal fentanyl citrate.

Kharasch ED, Whittington D, Hoffer C. Kharasch ED, et al. Anesthesiology. 2004 Sep;101(3):729-37. doi: 10.1097/00000542-200409000-00022. Anesthesiology. 2004. PMID: 15329598 Free article. Clinical Trial.

4

Influence of age on the pharmacokinetics and pharmacodynamics of oral transmucosal fentanyl citrate.

Kharasch ED, Hoffer C, Whittington D. Kharasch ED, et al. Anesthesiology. 2004 Sep;101(3):738-43. doi: 10.1097/00000542-200409000-00023. Anesthesiology. 2004. PMID: 15329599 Free article.

5

New insights into the mechanism of methoxyflurane nephrotoxicity and implications for anesthetic development (part 1): Identification of the nephrotoxic metabolic pathway.

Kharasch ED, Schroeder JL, Liggitt HD, Park SB, Whittington D, Sheffels P. Kharasch ED, et al. Anesthesiology. 2006 Oct;105(4):726-36. doi: 10.1097/00000542-200610000-00019. Anesthesiology. 2006. PMID: 17006072 Free article.

6

Role of CYP2B6 in stereoselective human methadone metabolism.

Totah RA, Sheffels P, Roberts T, Whittington D, Thummel K, Kharasch ED. Totah RA, et al. Among authors: kharasch ed. Anesthesiology. 2008 Mar;108(3):363-74. doi: 10.1097/ALN.0b013e3181642938. Anesthesiology. 2008. PMID: 18292673 Free article.

7

Methadone pharmacokinetics are independent of cytochrome P4503A (CYP3A) activity and gastrointestinal drug transport: insights from methadone interactions with ritonavir/indinavir.

Kharasch ED, Hoffer C, Whittington D, Walker A, Bedynek PS. Kharasch ED, et al. Anesthesiology. 2009 Mar;110(3):660-72. doi: 10.1097/ALN.0b013e3181986a9a. Anesthesiology. 2009. PMID: 19225389 Free PMC article.

8

Buprenorphine metabolites, buprenorphine-3-glucuronide and norbuprenorphine-3-glucuronide, are biologically active.

Brown SM, Holtzman M, Kim T, Kharasch ED. Brown SM, et al. Among authors: kharasch ed. Anesthesiology. 2011 Dec;115(6):1251-60. doi: 10.1097/ALN.0b013e318238fea0. Anesthesiology. 2011. PMID: 22037640 Free PMC article.

9

Perioperative pharmacokinetics of methadone in adolescents.

Sharma A, Tallchief D, Blood J, Kim T, London A, Kharasch ED. Sharma A, et al. Among authors: kharasch ed. Anesthesiology. 2011 Dec;115(6):1153-61. doi: 10.1097/ALN.0b013e318238fec5. Anesthesiology. 2011. PMID: 22037641 Free PMC article.

10

Lack of indinavir effects on methadone disposition despite inhibition of hepatic and intestinal cytochrome P4503A (CYP3A).

Kharasch ED, Bedynek PS, Hoffer C, Walker A, Whittington D. Kharasch ED, et al. Anesthesiology. 2012 Feb;116(2):432-47. doi: 10.1097/ALN.0b013e3182423478. Anesthesiology. 2012. PMID: 22273859 Free PMC article.

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