Nekkanti S - Search Results

1

DNA-binding affinity and anticancer activity of β-carboline-chalcone conjugates as potential DNA intercalators: Molecular modelling and synthesis.

Shankaraiah N, Siraj KP, Nekkanti S, Srinivasulu V, Sharma P, Senwar KR, Sathish M, Vishnuvardhan MV, Ramakrishna S, Jadala C, Nagesh N, Kamal A. Shankaraiah N, et al. Among authors: nekkanti s. Bioorg Chem. 2015 Apr;59:130-9. doi: 10.1016/j.bioorg.2015.02.007. Epub 2015 Mar 5. Bioorg Chem. 2015. PMID: 25771335

2

Design, synthesis and anticancer evaluation of tetrahydro-β-carboline-hydantoin hybrids.

Shankaraiah N, Nekkanti S, Chudasama KJ, Senwar KR, Sharma P, Jeengar MK, Naidu VG, Srinivasulu V, Srinivasulu G, Kamal A. Shankaraiah N, et al. Among authors: nekkanti s. Bioorg Med Chem Lett. 2014 Dec 1;24(23):5413-7. doi: 10.1016/j.bmcl.2014.10.038. Bioorg Med Chem Lett. 2014. PMID: 25453799

3

Dithiocarbamate/piperazine bridged pyrrolobenzodiazepines as DNA-minor groove binders: synthesis, DNA-binding affinity and cytotoxic activity.

Kamal A, Sreekanth K, Shankaraiah N, Sathish M, Nekkanti S, Srinivasulu V. Kamal A, et al. Among authors: nekkanti s. Bioorg Chem. 2015 Apr;59:23-30. doi: 10.1016/j.bioorg.2015.01.002. Epub 2015 Jan 28. Bioorg Chem. 2015. PMID: 25665519

4

One-pot synthesis of podophyllotoxin-thiourea congeners by employing NH₂SO₃H/NaI: Anticancer activity, DNA topoisomerase-II inhibition, and apoptosis inducing agents.

Shankaraiah N, Kumar NP, Amula SB, Nekkanti S, Jeengar MK, Naidu VG, Reddy TS, Kamal A. Shankaraiah N, et al. Among authors: nekkanti s. Bioorg Med Chem Lett. 2015 Oct 1;25(19):4239-44. doi: 10.1016/j.bmcl.2015.07.100. Epub 2015 Aug 6. Bioorg Med Chem Lett. 2015. PMID: 26292628

5

Design and synthesis of C3-tethered 1,2,3-triazolo-β-carboline derivatives: Anticancer activity, DNA-binding ability, viscosity and molecular modeling studies.

Shankaraiah N, Jadala C, Nekkanti S, Senwar KR, Nagesh N, Shrivastava S, Naidu VG, Sathish M, Kamal A. Shankaraiah N, et al. Among authors: nekkanti s. Bioorg Chem. 2016 Feb;64:42-50. doi: 10.1016/j.bioorg.2015.11.005. Epub 2015 Nov 23. Bioorg Chem. 2016. PMID: 26657602

6

Design and synthesis of 1,2,3-triazolo-phenanthrene hybrids as cytotoxic agents.

Kumar NP, Nekkanti S, Sujana Kumari S, Sharma P, Shankaraiah N. Kumar NP, et al. Among authors: nekkanti s. Bioorg Med Chem Lett. 2017 Jun 1;27(11):2369-2376. doi: 10.1016/j.bmcl.2017.04.022. Epub 2017 Apr 7. Bioorg Med Chem Lett. 2017. PMID: 28431881

7

Synthesis of different heterocycles-linked chalcone conjugates as cytotoxic agents and tubulin polymerization inhibitors.

Shankaraiah N, Nekkanti S, Brahma UR, Praveen Kumar N, Deshpande N, Prasanna D, Senwar KR, Jaya Lakshmi U. Shankaraiah N, et al. Among authors: nekkanti s. Bioorg Med Chem. 2017 Sep 1;25(17):4805-4816. doi: 10.1016/j.bmc.2017.07.031. Epub 2017 Jul 21. Bioorg Med Chem. 2017. PMID: 28774575

8

Synthesis of substituted phenanthrene-9-benzimidazole conjugates: Cytotoxicity evaluation and apoptosis inducing studies.

Kumar NP, Sharma P, Kumari SS, Brahma U, Nekkanti S, Shankaraiah N, Kamal A. Kumar NP, et al. Among authors: nekkanti s. Eur J Med Chem. 2017 Nov 10;140:128-140. doi: 10.1016/j.ejmech.2017.09.006. Epub 2017 Sep 8. Eur J Med Chem. 2017. PMID: 28923381

9

Synthesis of podophyllotoxin linked β-carboline congeners as potential anticancer agents and DNA topoisomerase II inhibitors.

Sathish M, Kavitha B, Nayak VL, Tangella Y, Ajitha A, Nekkanti S, Alarifi A, Shankaraiah N, Nagesh N, Kamal A. Sathish M, et al. Among authors: nekkanti s. Eur J Med Chem. 2018 Jan 20;144:557-571. doi: 10.1016/j.ejmech.2017.12.055. Epub 2017 Dec 16. Eur J Med Chem. 2018. PMID: 29289881

10

Synthesis of DNA interactive C3-trans-cinnamide linked β-carboline conjugates as potential cytotoxic and DNA topoisomerase I inhibitors.

Sathish M, Chetan Dushantrao S, Nekkanti S, Tokala R, Thatikonda S, Tangella Y, Srinivas G, Cherukommu S, Hari Krishna N, Shankaraiah N, Nagesh N, Kamal A. Sathish M, et al. Among authors: nekkanti s. Bioorg Med Chem. 2018 Sep 15;26(17):4916-4929. doi: 10.1016/j.bmc.2018.08.031. Epub 2018 Aug 25. Bioorg Med Chem. 2018. PMID: 30172625

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