Single A - Search Results

1

Synthetic Lethal Screens Identify Vulnerabilities in GPCR Signaling and Cytoskeletal Organization in E-Cadherin-Deficient Cells.

Telford BJ, Chen A, Beetham H, Frick J, Brew TP, Gould CM, Single A, Godwin T, Simpson KJ, Guilford P. Telford BJ, et al. Among authors: single a. Mol Cancer Ther. 2015 May;14(5):1213-23. doi: 10.1158/1535-7163.MCT-14-1092. Epub 2015 Mar 16. Mol Cancer Ther. 2015. PMID: 25777964

2

E-cadherin-deficient cells have synthetic lethal vulnerabilities in plasma membrane organisation, dynamics and function.

Godwin TD, Kelly ST, Brew TP, Bougen-Zhukov NM, Single AB, Chen A, Stylianou CE, Harris LD, Currie SK, Telford BJ, Beetham HG, Evans GB, Black MA, Guilford PJ. Godwin TD, et al. Among authors: single ab. Gastric Cancer. 2019 Mar;22(2):273-286. doi: 10.1007/s10120-018-0859-1. Epub 2018 Jul 31. Gastric Cancer. 2019. PMID: 30066183 Free PMC article.

3

A Comparison of Real-Time and Endpoint Cell Viability Assays for Improved Synthetic Lethal Drug Validation.

Single A, Beetham H, Telford BJ, Guilford P, Chen A. Single A, et al. J Biomol Screen. 2015 Dec;20(10):1286-93. doi: 10.1177/1087057115605765. Epub 2015 Sep 17. J Biomol Screen. 2015. PMID: 26384394

4

A high-throughput screen to identify novel synthetic lethal compounds for the treatment of E-cadherin-deficient cells.

Beetham H, Chen A, Telford BJ, Single A, Jarman KE, Lackovic K, Luxenburger A, Guilford P. Beetham H, et al. Among authors: single a. Sci Rep. 2019 Aug 29;9(1):12511. doi: 10.1038/s41598-019-48929-0. Sci Rep. 2019. PMID: 31467357 Free PMC article.

5

Allosteric AKT Inhibitors Target Synthetic Lethal Vulnerabilities in E-Cadherin-Deficient Cells.

Bougen-Zhukov N, Nouri Y, Godwin T, Taylor M, Hakkaart C, Single A, Brew T, Permina E, Chen A, Black MA, Guilford P. Bougen-Zhukov N, et al. Among authors: single a. Cancers (Basel). 2019 Sep 13;11(9):1359. doi: 10.3390/cancers11091359. Cancers (Basel). 2019. PMID: 31540244 Free PMC article.

6

Negative urgency increases risk for coping-motivated cannabis outcomes in socially anxious male emerging adult cannabis users.

Single A, Mota N, Keough MT. Single A, et al. J Am Coll Health. 2024 Dec 6:1-8. doi: 10.1080/07448481.2024.2435936. Online ahead of print. J Am Coll Health. 2024. PMID: 39642003

7

The three-domain impact framework for characterizing impact of patient involvement in health technology assessment.

Lopez Gousset V, Silveira Silva A, Holtorf AP, Toledo-Chávarri A, Single A. Lopez Gousset V, et al. Among authors: single a. Int J Technol Assess Health Care. 2024 Nov 11;40(1):e52. doi: 10.1017/S0266462324000400. Int J Technol Assess Health Care. 2024. PMID: 39523886 Free PMC article.

8

LSD1 drives intestinal epithelial maturation and controls small intestinal immune cell composition independent of microbiota in a murine model.

Díez-Sánchez A, Lindholm HT, Vornewald PM, Ostrop J, Yao R, Single AB, Marstad A, Parmar N, Shaw TN, Martín-Alonso M, Oudhoff MJ. Díez-Sánchez A, et al. Among authors: single ab. Nat Commun. 2024 Apr 22;15(1):3412. doi: 10.1038/s41467-024-47815-2. Nat Commun. 2024. PMID: 38649356 Free PMC article.

9

Cannabis use and social anxiety disorder in emerging adulthood: Results from a nationally representative sample.

Single A, Alcolado G, Keough MT, Mota N. Single A, et al. J Anxiety Disord. 2024 Jan;101:102808. doi: 10.1016/j.janxdis.2023.102808. Epub 2023 Dec 4. J Anxiety Disord. 2024. PMID: 38061325

10

Effectiveness of a web-based self-help tool to reduce problem gambling: A randomized controlled trial.

Boumparis N, Baumgartner C, Malischnig D, Wenger A, Achab S, Khazaal Y, Keough MT, Hodgins DC, Bilevicius E, Single A, Haug S, Schaub MP. Boumparis N, et al. Among authors: single a. J Behav Addict. 2023 Sep 1;12(3):744-757. doi: 10.1556/2006.2023.00045. Print 2023 Oct 5. J Behav Addict. 2023. PMID: 37659086 Free PMC article. Clinical Trial.

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