Hu S - Search Results

1

N-Heterocyclic carbene-catalyzed annulation of cyclic β-enamino esters with enals: access to functionalized indolo[2,3-a]quinolizidines.

Hu S, Wang B, Zhang Y, Tang W, Fang M, Lu T, Du D. Hu S, et al. Org Biomol Chem. 2015 Apr 28;13(16):4661-7. doi: 10.1039/c5ob00176e. Org Biomol Chem. 2015. PMID: 25799005

2

Fragment-based strategy for structural optimization in combination with 3D-QSAR.

Yuan H, Tai W, Hu S, Liu H, Zhang Y, Yao S, Ran T, Lu S, Ke Z, Xiong X, Xu J, Chen Y, Lu T. Yuan H, et al. Among authors: hu s. J Comput Aided Mol Des. 2013 Oct;27(10):897-915. doi: 10.1007/s10822-013-9687-x. Epub 2013 Nov 1. J Comput Aided Mol Des. 2013. PMID: 24178966

3

Molecular modeling of exquisitely selective c-Met inhibitors through 3D-QSAR and molecular dynamics simulations.

Yuan H, Zhuang J, Hu S, Li H, Xu J, Hu Y, Xiong X, Chen Y, Lu T. Yuan H, et al. Among authors: hu s, hu y. J Chem Inf Model. 2014 Sep 22;54(9):2544-54. doi: 10.1021/ci500268s. Epub 2014 Sep 9. J Chem Inf Model. 2014. PMID: 25181449

4

Discovery, optimization and biological evaluation for novel c-Met kinase inhibitors.

Yuan H, Liu Q, Zhang L, Hu S, Chen T, Li H, Chen Y, Xu Y, Lu T. Yuan H, et al. Among authors: hu s. Eur J Med Chem. 2018 Jan 1;143:491-502. doi: 10.1016/j.ejmech.2017.11.073. Epub 2017 Dec 2. Eur J Med Chem. 2018. PMID: 29202410

5

Self [3 + 4] Cycloadditions of Isatin N, N'-Cyclic Azomethine Imine 1,3-Dipole with N-( o-Chloromethyl)aryl Amides.

Jin Q, Zhang J, Jiang C, Zhang D, Gao M, Hu S. Jin Q, et al. Among authors: hu s. J Org Chem. 2018 Aug 3;83(15):8410-8416. doi: 10.1021/acs.joc.8b01055. Epub 2018 Jun 11. J Org Chem. 2018. PMID: 29846070

6

Direct Cyclopropanation of Quinolinium Zwitterionic Thiolates via Dearomative Reactions.

Jin Q, Jiang C, Gao M, Zhang D, Hu S, Zhang J. Jin Q, et al. Among authors: hu s. J Org Chem. 2021 Nov 5;86(21):15640-15647. doi: 10.1021/acs.joc.1c02175. Epub 2021 Oct 21. J Org Chem. 2021. PMID: 34672589

7

Discovery and Structural Optimization of Novel Quinolone Derivatives as Potent Irreversible Pan-Fibroblast Growth Factor Receptor Inhibitors for Treating Solid Tumors.

Hu S, Liu Y, Ma J, Ding W, Chen H, Jiang H, Chen H, Wei S, Liu Y, Jin Q, Yuan H, Yan L. Hu S, et al. J Med Chem. 2023 Jul 13;66(13):8858-8875. doi: 10.1021/acs.jmedchem.3c00455. Epub 2023 Jun 19. J Med Chem. 2023. PMID: 37335602

8

Design, synthesis and docking studies of novel dipeptidyl boronic acid proteasome inhibitors constructed from αα- and αβ-amino acids.

Shi J, Lei M, Wu W, Feng H, Wang J, Chen S, Zhu Y, Hu S, Liu Z, Jiang C. Shi J, et al. Among authors: hu s. Bioorg Med Chem Lett. 2016 Apr 15;26(8):1958-62. doi: 10.1016/j.bmcl.2016.03.007. Epub 2016 Mar 3. Bioorg Med Chem Lett. 2016. PMID: 26965867

9

Design, synthesis, SAR discussion, in vitro and in vivo evaluation of novel selective EGFR modulator to inhibit L858R/T790M double mutants.

Zhang H, Wu W, Feng C, Liu Z, Bai E, Wang X, Lei M, Cheng H, Feng H, Shi J, Wang J, Zhang Z, Jin T, Chen S, Hu S, Zhu Y. Zhang H, et al. Among authors: hu s. Eur J Med Chem. 2017 Jul 28;135:12-23. doi: 10.1016/j.ejmech.2017.04.036. Epub 2017 Apr 14. Eur J Med Chem. 2017. PMID: 28426996

10

3D-QSAR-aided design, synthesis, in vitro and in vivo evaluation of dipeptidyl boronic acid proteasome inhibitors and mechanism studies.

Lei M, Feng H, Wang C, Li H, Shi J, Wang J, Liu Z, Chen S, Hu S, Zhu Y. Lei M, et al. Among authors: hu s. Bioorg Med Chem. 2016 Jun 1;24(11):2576-2588. doi: 10.1016/j.bmc.2016.04.025. Epub 2016 Apr 13. Bioorg Med Chem. 2016. PMID: 27117691

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