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RUNX2 in mammary gland development and breast cancer.
Ferrari N, McDonald L, Morris JS, Cameron ER, Blyth K. Ferrari N, et al. Among authors: mcdonald l. J Cell Physiol. 2013 Jun;228(6):1137-42. doi: 10.1002/jcp.24285. J Cell Physiol. 2013. PMID: 23169547 Review.
Runx2 contributes to the regenerative potential of the mammary epithelium.
Ferrari N, Riggio AI, Mason S, McDonald L, King A, Higgins T, Rosewell I, Neil JC, Smalley MJ, Sansom OJ, Morris J, Cameron ER, Blyth K. Ferrari N, et al. Among authors: mcdonald l. Sci Rep. 2015 Oct 22;5:15658. doi: 10.1038/srep15658. Sci Rep. 2015. PMID: 26489514 Free PMC article.
Runx2 in normal tissues and cancer cells: A developing story.
Blyth K, Vaillant F, Jenkins A, McDonald L, Pringle MA, Huser C, Stein T, Neil J, Cameron ER. Blyth K, et al. Among authors: mcdonald l. Blood Cells Mol Dis. 2010 Aug 15;45(2):117-23. doi: 10.1016/j.bcmd.2010.05.007. Epub 2010 Jun 26. Blood Cells Mol Dis. 2010. PMID: 20580290
RUNX2 correlates with subtype-specific breast cancer in a human tissue microarray, and ectopic expression of Runx2 perturbs differentiation in the mouse mammary gland.
McDonald L, Ferrari N, Terry A, Bell M, Mohammed ZM, Orange C, Jenkins A, Muller WJ, Gusterson BA, Neil JC, Edwards J, Morris JS, Cameron ER, Blyth K. McDonald L, et al. Dis Model Mech. 2014 May;7(5):525-34. doi: 10.1242/dmm.015040. Epub 2014 Mar 13. Dis Model Mech. 2014. PMID: 24626992 Free PMC article.
RUNX1 Is a Driver of Renal Cell Carcinoma Correlating with Clinical Outcome.
Rooney N, Mason SM, McDonald L, Däbritz JHM, Campbell KJ, Hedley A, Howard S, Athineos D, Nixon C, Clark W, Leach JDG, Sansom OJ, Edwards J, Cameron ER, Blyth K. Rooney N, et al. Among authors: mcdonald l. Cancer Res. 2020 Jun 1;80(11):2325-2339. doi: 10.1158/0008-5472.CAN-19-3870. Epub 2020 Mar 10. Cancer Res. 2020. PMID: 32156779 Free article.
N-WASP coordinates the delivery and F-actin-mediated capture of MT1-MMP at invasive pseudopods.
Yu X, Zech T, McDonald L, Gonzalez EG, Li A, Macpherson I, Schwarz JP, Spence H, Futó K, Timpson P, Nixon C, Ma Y, Anton IM, Visegrády B, Insall RH, Oien K, Blyth K, Norman JC, Machesky LM. Yu X, et al. Among authors: mcdonald l. J Cell Biol. 2012 Oct 29;199(3):527-44. doi: 10.1083/jcb.201203025. Epub 2012 Oct 22. J Cell Biol. 2012. PMID: 23091069 Free PMC article.
Secreted CLIC3 drives cancer progression through its glutathione-dependent oxidoreductase activity.
Hernandez-Fernaud JR, Ruengeler E, Casazza A, Neilson LJ, Pulleine E, Santi A, Ismail S, Lilla S, Dhayade S, MacPherson IR, McNeish I, Ennis D, Ali H, Kugeratski FG, Al Khamici H, van den Biggelaar M, van den Berghe PV, Cloix C, McDonald L, Millan D, Hoyle A, Kuchnio A, Carmeliet P, Valenzuela SM, Blyth K, Yin H, Mazzone M, Norman JC, Zanivan S. Hernandez-Fernaud JR, et al. Among authors: mcdonald l. Nat Commun. 2017 Feb 15;8:14206. doi: 10.1038/ncomms14206. Nat Commun. 2017. PMID: 28198360 Free PMC article.
Optimizing metastatic-cascade-dependent Rac1 targeting in breast cancer: Guidance using optical window intravital FRET imaging.
Floerchinger A, Murphy KJ, Latham SL, Warren SC, McCulloch AT, Lee YK, Stoehr J, Mélénec P, Guaman CS, Metcalf XL, Lee V, Zaratzian A, Da Silva A, Tayao M, Rolo S, Phimmachanh M, Sultani G, McDonald L, Mason SM, Ferrari N, Ooms LM, Johnsson AE, Spence HJ, Olson MF, Machesky LM, Sansom OJ, Morton JP, Mitchell CA, Samuel MS, Croucher DR, Welch HCE, Blyth K, Caldon CE, Herrmann D, Anderson KI, Timpson P, Nobis M. Floerchinger A, et al. Among authors: mcdonald l. Cell Rep. 2021 Sep 14;36(11):109689. doi: 10.1016/j.celrep.2021.109689. Cell Rep. 2021. PMID: 34525350 Free article.
Structure-based design, synthesis and biological evaluation of a novel series of isoquinolone and pyrazolo[4,3-c]pyridine inhibitors of fascin 1 as potential anti-metastatic agents.
Francis S, Croft D, Schüttelkopf AW, Parry C, Pugliese A, Cameron K, Claydon S, Drysdale M, Gardner C, Gohlke A, Goodwin G, Gray CH, Konczal J, McDonald L, Mezna M, Pannifer A, Paul NR, Machesky L, McKinnon H, Bower J. Francis S, et al. Among authors: mcdonald l. Bioorg Med Chem Lett. 2019 Apr 15;29(8):1023-1029. doi: 10.1016/j.bmcl.2019.01.035. Epub 2019 Jan 30. Bioorg Med Chem Lett. 2019. PMID: 30773430 Free PMC article.
1,021 results